FI54125C - Foerfarande foer framstaellning av anti-inflammatoriska tetrahydropyrano(3,4-b)-indol-1-aettiksyraderivat - Google Patents

Foerfarande foer framstaellning av anti-inflammatoriska tetrahydropyrano(3,4-b)-indol-1-aettiksyraderivat

Info

Publication number
FI54125C
FI54125C FI1511/72A FI151172A FI54125C FI 54125 C FI54125 C FI 54125C FI 1511/72 A FI1511/72 A FI 1511/72A FI 151172 A FI151172 A FI 151172A FI 54125 C FI54125 C FI 54125C
Authority
FI
Finland
Prior art keywords
xrader
tetrahydropyrano
indol
inflammatory
acetic
Prior art date
Application number
FI1511/72A
Other languages
English (en)
Finnish (fi)
Other versions
FI54125B (fi
Inventor
Christopher Alexander Demerson
Leslie George Humber
Thomas Albert Dobson
Ivo Ladislav Jirkovsky
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22527916&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI54125(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by American Home Prod filed Critical American Home Prod
Publication of FI54125B publication Critical patent/FI54125B/fi
Application granted granted Critical
Publication of FI54125C publication Critical patent/FI54125C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • H—ELECTRICITY
    • H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10D—INORGANIC ELECTRIC SEMICONDUCTOR DEVICES
    • H10D10/00—Bipolar junction transistors [BJT]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FI1511/72A 1971-06-01 1972-05-30 Foerfarande foer framstaellning av anti-inflammatoriska tetrahydropyrano(3,4-b)-indol-1-aettiksyraderivat FI54125C (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00148895A US3843681A (en) 1971-06-01 1971-06-01 1-carboxamido pyrano(thiopyrano)(3,4-6)indole derivatives

Publications (2)

Publication Number Publication Date
FI54125B FI54125B (fi) 1978-06-30
FI54125C true FI54125C (fi) 1978-10-10

Family

ID=22527916

Family Applications (1)

Application Number Title Priority Date Filing Date
FI1511/72A FI54125C (fi) 1971-06-01 1972-05-30 Foerfarande foer framstaellning av anti-inflammatoriska tetrahydropyrano(3,4-b)-indol-1-aettiksyraderivat

Country Status (23)

Country Link
US (1) US3843681A (cg-RX-API-DMAC7.html)
JP (1) JPS5638594B1 (cg-RX-API-DMAC7.html)
AR (1) AR198787A1 (cg-RX-API-DMAC7.html)
AU (1) AU463079B2 (cg-RX-API-DMAC7.html)
BE (1) BE784284A (cg-RX-API-DMAC7.html)
CA (1) CA1006875A (cg-RX-API-DMAC7.html)
CH (1) CH580101A5 (cg-RX-API-DMAC7.html)
CS (1) CS178409B2 (cg-RX-API-DMAC7.html)
DE (1) DE2226340A1 (cg-RX-API-DMAC7.html)
DK (1) DK155328C (cg-RX-API-DMAC7.html)
ES (1) ES403343A1 (cg-RX-API-DMAC7.html)
FI (1) FI54125C (cg-RX-API-DMAC7.html)
FR (1) FR2140154B1 (cg-RX-API-DMAC7.html)
GB (1) GB1391005A (cg-RX-API-DMAC7.html)
HK (1) HK13078A (cg-RX-API-DMAC7.html)
HU (1) HU169432B (cg-RX-API-DMAC7.html)
IL (1) IL39466A (cg-RX-API-DMAC7.html)
MY (1) MY7800237A (cg-RX-API-DMAC7.html)
NL (1) NL173405C (cg-RX-API-DMAC7.html)
PH (2) PH10625A (cg-RX-API-DMAC7.html)
SE (1) SE387122B (cg-RX-API-DMAC7.html)
SU (1) SU463262A3 (cg-RX-API-DMAC7.html)
ZA (1) ZA723344B (cg-RX-API-DMAC7.html)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
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US3974179A (en) * 1971-06-01 1976-08-10 American Home Products Corporation 1,3,4,9-Tetrahydropyrano[3,4-b]indole-1-acetamides and derivatives
US4118394A (en) * 1976-10-18 1978-10-03 Ayerst, Mckenna & Harrison Limited Pyrano- and thiopyranoindole derivatives
US4179503A (en) * 1978-05-08 1979-12-18 American Home Products Corp. 1-Hydroxyalkanamine pyrano[3,4-b]indole derivatives
US4309348A (en) * 1979-05-14 1982-01-05 American Home Products Corporation Tricyclic indole derivatives
US4235903A (en) * 1979-08-06 1980-11-25 American Home Products Corporation 1-Hydroxyalkanamine tetrahydrocarbazoles and cyclopent[b]indoles, compositions and method of use
US4319029A (en) * 1979-08-06 1982-03-09 American Home Products Corporation Hydroxyalkanamide tetrahydrocarbazoles
JPS58179164A (ja) * 1982-04-10 1983-10-20 Toshiharu Nakai 金属表面処理等に用いられるｓｃｒ整流器の定格直流電圧選定方法並びに定格直流電圧切替方法
US4775690A (en) * 1987-01-13 1988-10-04 American Home Products Corporation Substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids
US4670462A (en) * 1986-03-11 1987-06-02 American Home Products Corporation Substituted 1,3,4,9-tetrahydropyrano(3,4-B)indole-1-acetic acids
US4971960A (en) * 1986-03-11 1990-11-20 American Home Products Corporation Substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids
US4826994A (en) * 1986-03-11 1989-05-02 American Home Products Corporation Production of substituted 1,3,4,9-tetrahydropyrano(3,4-B)indole-1-acetic acids
US4663345A (en) * 1986-04-17 1987-05-05 American Home Products Corporation Etodolac for treatment of gout
US4686213A (en) * 1986-08-15 1987-08-11 American Home Products Corporation Substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids
US4748252A (en) * 1986-08-15 1988-05-31 American Home Products Corporation Substituted 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acids
US4810699A (en) * 1987-02-20 1989-03-07 American Home Products Corporation Substituted 1,3,4,9-tetrahydropyrano[3,4,-b]indole-1-acetic acids, pharmaceutical compositions containing them, and methods for treating inflammatory conditions and for analgesic purposes using them
US4824961A (en) * 1987-08-27 1989-04-25 American Home Products Corporation Production of substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids
US4897493A (en) * 1987-08-27 1990-01-30 American Home Products Corporation Production of substituted 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acids
US4822781A (en) * 1987-10-08 1989-04-18 American Home Products Substituted-8-alkenyl-1,3,4,9-tetrahydropyrano-[3,4-b]indole-1-acetic acids
US4822893A (en) * 1988-02-08 1989-04-18 American Home Products Production of substituted 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acids
US4873257A (en) * 1988-04-21 1989-10-10 American Home Products Corporation Susbtituted fused tetrahydrocarbazole acetic acid derivatives
EP0727994B1 (en) * 1992-03-13 2000-06-07 Sepracor, Inc. Antipyretic and analgesic methods and compositions containing optically pure r-etodolac
IT1288123B1 (it) * 1996-09-04 1998-09-10 Nicox Sa Uso di nitroderivati per l'incontinenza urinaria
US6103765A (en) * 1997-07-09 2000-08-15 Androsolutions, Inc. Methods for treating male erectile dysfunction
AU742787B2 (en) 1997-07-09 2002-01-10 Androsolutions, Inc. Improved methods and compositions for treating male erectile dysfunction
EP1104297B8 (en) 1998-07-09 2006-05-03 Cephalon, Inc. Compositions for the treatment of chronic lymphocytic leukemia
US6066741A (en) * 1998-09-08 2000-05-23 A.M.S.A. Anonima Materie Sintetiche & Affini S.P.A. Process for the preparation of etodolac
IT1308633B1 (it) 1999-03-02 2002-01-09 Nicox Sa Nitrossiderivati.
US7129262B2 (en) * 1999-07-23 2006-10-31 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US6545034B1 (en) * 1999-07-23 2003-04-08 The Regents Of The University Of California Use of etodolac for the treatment of chronic lymphocytic leukemia
US7361680B2 (en) * 1999-07-23 2008-04-22 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US7105560B1 (en) * 1999-07-23 2006-09-12 The Regents Of The University Of California Use of etodolac in the treatment of multiple myeloma
US7151100B1 (en) * 1999-07-23 2006-12-19 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
IT1318673B1 (it) * 2000-08-08 2003-08-27 Nicox Sa Farmaci per le disfunzioni sessuali.
IT1318674B1 (it) * 2000-08-08 2003-08-27 Nicox Sa Faramaci per l'incontinenza.
AU2001283224B2 (en) * 2000-08-09 2007-06-28 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US20040152672A1 (en) * 2000-08-09 2004-08-05 Carson Dennis A. Indole compounds useful for the treatment of cancer
US6544556B1 (en) 2000-09-11 2003-04-08 Andrx Corporation Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor
US7601846B2 (en) * 2001-06-26 2009-10-13 The Regents Of The University Of California Compounds having activity as inhibitors of apoptosis
US20030232794A1 (en) * 2001-06-26 2003-12-18 Cottam Howard B. Use of STAT-6 inhibitors as therapeutic agents
AU2003217676B2 (en) 2002-02-22 2009-06-11 Takeda Pharmaceutical Company Limited Active agent delivery systems and methods for protecting and administering active agents
ITMI20020773A1 (it) * 2002-04-11 2003-10-13 Nicox Sa Farmaci per il trattamento dell'artrite
TW200400963A (en) 2002-05-21 2004-01-16 Wyeth Corp R-enantiomers of pyranoindole derivatives and the use thereof for the treatment of hepatitis C virus infection or disease
TW200400818A (en) 2002-05-21 2004-01-16 Wyeth Corp Method for the use of pyranoindole derivatives to treat infection with hepatitis C virus
US7211599B2 (en) * 2002-09-19 2007-05-01 The Regents Of The University Of California Use of etodolac to treat hyperplasia
DE10252667A1 (de) * 2002-11-11 2004-05-27 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
TW200524940A (en) * 2003-10-02 2005-08-01 Salmedix Inc Indole derivatives
DE10360792A1 (de) * 2003-12-23 2005-07-28 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
JP2008512496A (ja) * 2004-09-10 2008-04-24 ワイス １，３，４，９−テトラヒドロピラノ［３，４−ｂ］インドール誘導体の大規模実施可能な合成方法
EP1683521A1 (en) * 2005-01-21 2006-07-26 Centre National De La Recherche Scientifique (Cnrs) Peptide deformylase inhibitors, their use, and pharmaceutical compositions containing the same
ES2418153T3 (es) 2006-03-08 2013-08-12 Cortria Corporation Terapia de combinación con inhibidores no selectivos de COX para prevenir lesiones gástricas relacionadas con COX
WO2010011316A1 (en) * 2008-07-23 2010-01-28 Arena Pharmaceuticals, Inc. SUBSTITUTED 1,2,3,4- TETRAHYDROCYCLOPENTA[b]INDOL-3-YL) ACETIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS

Also Published As

Publication number Publication date
HK13078A (en) 1978-03-17
PH11673A (en) 1978-05-19
BE784284A (fr) 1972-12-01
CS178409B2 (cg-RX-API-DMAC7.html) 1977-09-15
MY7800237A (en) 1978-12-31
CH580101A5 (cg-RX-API-DMAC7.html) 1976-09-30
GB1391005A (en) 1975-04-16
SE387122B (sv) 1976-08-30
FR2140154A1 (cg-RX-API-DMAC7.html) 1973-01-12
DE2226340C2 (cg-RX-API-DMAC7.html) 1987-07-16
ZA723344B (en) 1973-12-19
AU4255472A (en) 1973-11-29
SU463262A3 (ru) 1975-03-05
FI54125B (fi) 1978-06-30
AR198787A1 (es) 1974-07-24
DE2226340A1 (de) 1973-03-15
JPS5638594B1 (cg-RX-API-DMAC7.html) 1981-09-08
US3843681A (en) 1974-10-22
PH10625A (en) 1977-07-21
NL173405C (nl) 1984-01-16
DK155328C (da) 1989-09-18
NL7207408A (cg-RX-API-DMAC7.html) 1972-12-05
DK155328B (da) 1989-03-28
FR2140154B1 (cg-RX-API-DMAC7.html) 1976-04-16
IL39466A (en) 1975-05-22
ES403343A1 (es) 1975-04-16
HU169432B (cg-RX-API-DMAC7.html) 1976-11-28
CA1006875A (en) 1977-03-15
IL39466A0 (en) 1972-07-26
AU463079B2 (en) 1975-07-17

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