FI51484C - Process for the preparation of 7beta- (D-5-amino-5-carboxy-valeramido) -3- (carbamoyloxymethyl) -7-methoxy-3-cephem-4-carboxylic acid antibiotic. - Google Patents

Process for the preparation of 7beta- (D-5-amino-5-carboxy-valeramido) -3- (carbamoyloxymethyl) -7-methoxy-3-cephem-4-carboxylic acid antibiotic.

Info

Publication number
FI51484C
FI51484C FI710711A FI71171A FI51484C FI 51484 C FI51484 C FI 51484C FI 710711 A FI710711 A FI 710711A FI 71171 A FI71171 A FI 71171A FI 51484 C FI51484 C FI 51484C
Authority
FI
Finland
Prior art keywords
valeramido
7beta
carbamoyloxymethyl
cephem
carboxy
Prior art date
Application number
FI710711A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI51484B (en
Inventor
Edward O Stapley
Justo M Mata
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/115,779 external-priority patent/US4302578A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Priority to FI751591A priority Critical patent/FI751591A/fi
Priority to FI751592A priority patent/FI51948C/en
Publication of FI51484B publication Critical patent/FI51484B/fi
Application granted granted Critical
Publication of FI51484C publication Critical patent/FI51484C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/08—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin disubstituted in the 7 position

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cephalosporin Compounds (AREA)
FI710711A 1970-03-13 1971-03-11 Process for the preparation of 7beta- (D-5-amino-5-carboxy-valeramido) -3- (carbamoyloxymethyl) -7-methoxy-3-cephem-4-carboxylic acid antibiotic. FI51484C (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FI751591A FI751591A (en) 1970-03-13 1975-05-30
FI751592A FI51948C (en) 1970-03-13 1975-05-30 Method 7beta- (D-5-amino-5-carboxivaleramido) -3- (alpha-methoxy-p-sulfoxoxycinnamoyloxyethyl) -7-methoxy-3-cephem-4-carboxylic acid and 7beta- (D-5-ammonium) -5-carboxivaleramido) -3- (alpha-methoxy-p-hydroxycinnamoyloxymethyl) -7-methoxy-3-cefen-4-k

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US1949670A 1970-03-13 1970-03-13
US5131970A 1970-06-30 1970-06-30
US9659470A 1970-12-09 1970-12-09
US05/115,779 US4302578A (en) 1970-12-09 1971-02-16 Cephalosporin antibiotics

Publications (2)

Publication Number Publication Date
FI51484B FI51484B (en) 1976-09-30
FI51484C true FI51484C (en) 1977-01-10

Family

ID=27486855

Family Applications (1)

Application Number Title Priority Date Filing Date
FI710711A FI51484C (en) 1970-03-13 1971-03-11 Process for the preparation of 7beta- (D-5-amino-5-carboxy-valeramido) -3- (carbamoyloxymethyl) -7-methoxy-3-cephem-4-carboxylic acid antibiotic.

Country Status (19)

Country Link
JP (1) JPS581919B1 (en)
AR (3) AR200370A1 (en)
BE (1) BE764160A (en)
CA (1) CA960169A (en)
CH (5) CH587856A5 (en)
DD (3) DD99166A5 (en)
DE (3) DE2109854C3 (en)
DK (1) DK131639C (en)
FI (1) FI51484C (en)
FR (1) FR2085702B1 (en)
GB (1) GB1321412A (en)
IE (1) IE35110B1 (en)
IL (1) IL36281A (en)
IT (1) IT1045524B (en)
NL (1) NL171285C (en)
NO (1) NO134219C (en)
PH (1) PH12292A (en)
SE (1) SE385713B (en)
YU (1) YU35164B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1040620A (en) * 1972-11-14 1978-10-17 Frank J. Urban 6-alkoxy-6-acylamidopenicillins 7-alkoxy-7-acylamido acetoxycephalosporins and process
US4065356A (en) 1976-02-12 1977-12-27 Merck & Co., Inc. Production of antibiotic FR-02A (efrotomycin) by streptomyces lactamdurans
US4327093A (en) 1978-10-24 1982-04-27 Fujisawa Pharmaceutical Co., Ltd. 3,7-Disubstituted-2 or 3-cephem-4-carboxylic acid compounds
JPS5931517B2 (en) * 1978-12-12 1984-08-02 山之内製薬株式会社 New 7↓-methoxycephalosporin derivative
US4379920A (en) * 1979-10-31 1983-04-12 Glaxo Group Limited Cephalosporins
EP0137365A3 (en) * 1983-09-06 1986-01-15 Takeda Chemical Industries, Ltd. Cephalosporins and their production
EP0160745A3 (en) * 1984-05-07 1986-11-05 Takeda Chemical Industries, Ltd. Cephem compounds and their production
ES2400562T3 (en) 2003-05-28 2013-04-10 Dsm Sinochem Pharmaceuticals Netherlands B.V. Cefem compound

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4945594A (en) * 1972-09-08 1974-05-01

Also Published As

Publication number Publication date
DE2109854C3 (en) 1975-06-05
YU35164B (en) 1980-09-25
PH12292A (en) 1978-12-29
DK131639C (en) 1976-01-12
DE2109854A1 (en) 1971-09-23
DE2166462A1 (en) 1974-05-09
DK131639B (en) 1975-08-11
IT1045524B (en) 1980-05-10
AR201142A1 (en) 1975-02-14
CH579576A5 (en) 1976-09-15
IL36281A (en) 1977-04-29
FR2085702B1 (en) 1974-08-23
DD96254A5 (en) 1973-03-12
DD100002A5 (en) 1973-09-05
NO134219B (en) 1976-05-24
IE35110B1 (en) 1975-11-12
YU62671A (en) 1979-12-31
SE385713B (en) 1976-07-19
BE764160A (en) 1971-09-13
CH586226A5 (en) 1977-03-31
FI51484B (en) 1976-09-30
IL36281A0 (en) 1971-04-28
AR200370A1 (en) 1974-11-08
GB1321412A (en) 1973-06-27
CA960169A (en) 1974-12-31
JPS581919B1 (en) 1983-01-13
DE2166462B2 (en) 1977-01-20
DE2109854B2 (en) 1974-09-26
CH587911A5 (en) 1977-05-13
AR212149A1 (en) 1978-05-31
DE2166463A1 (en) 1974-05-02
NL7103360A (en) 1971-09-15
IE35110L (en) 1971-09-13
FR2085702A1 (en) 1971-12-31
NL171285B (en) 1982-10-01
CH589655A5 (en) 1977-07-15
NO134219C (en) 1976-09-01
CH587856A5 (en) 1977-05-13
DD99166A5 (en) 1973-07-20
NL171285C (en) 1983-03-01

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