DK131639B - Process for the preparation of 7beta- (D-5-amino-5-carboxyvaleramido) -3- (carbamoyloxymethyl) -7-methoxy-3-cephem-4-carboxylic acid or pharmaceutically acceptable salts thereof. - Google Patents

Process for the preparation of 7beta- (D-5-amino-5-carboxyvaleramido) -3- (carbamoyloxymethyl) -7-methoxy-3-cephem-4-carboxylic acid or pharmaceutically acceptable salts thereof.

Info

Publication number
DK131639B
DK131639B DK118171AA DK118171A DK131639B DK 131639 B DK131639 B DK 131639B DK 118171A A DK118171A A DK 118171AA DK 118171 A DK118171 A DK 118171A DK 131639 B DK131639 B DK 131639B
Authority
DK
Denmark
Prior art keywords
carboxyvaleramido
7beta
carbamoyloxymethyl
cephem
methoxy
Prior art date
Application number
DK118171AA
Other languages
Danish (da)
Other versions
DK131639C (en
Inventor
Edward O Stapley
Justo M Mata
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/115,779 external-priority patent/US4302578A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Priority to DK517973A priority Critical patent/DK134324B/en
Publication of DK131639B publication Critical patent/DK131639B/en
Application granted granted Critical
Publication of DK131639C publication Critical patent/DK131639C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/08—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin disubstituted in the 7 position

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cephalosporin Compounds (AREA)
DK118171A 1970-03-13 1971-03-12 PROCEDURE FOR THE PREPARATION OF 7BETA- (D-5-AMINO-5-CARBOXYVALERAMIDO) -3- (CARBAMOYLOXYMETHYL) -7-METHOXY-3-CEPHEM-4-CARBOXYLIC ACID OR SALPER ACALPH DK131639C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK517973A DK134324B (en) 1970-03-13 1973-09-21 Process for the preparation of 7beta- (D-5-amino-5-carboxyvaleramido) -3- (alpha-methoxy-p-sulfooxycinnamoyloxymethyl) -7-methoxy-3-cephem-4-carboxylic acid or 7beta- (D-5-amino -5-carboxyvaleramido) -3- (alpha-methoxy-p-hydroxycinnamoyloxymethyl) -7-methoxy-3-cephem-4-carboxylic acid or a mixture thereof.

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US1949670A 1970-03-13 1970-03-13
US5131970A 1970-06-30 1970-06-30
US9659470A 1970-12-09 1970-12-09
US05/115,779 US4302578A (en) 1970-12-09 1971-02-16 Cephalosporin antibiotics

Publications (2)

Publication Number Publication Date
DK131639B true DK131639B (en) 1975-08-11
DK131639C DK131639C (en) 1976-01-12

Family

ID=27486855

Family Applications (1)

Application Number Title Priority Date Filing Date
DK118171A DK131639C (en) 1970-03-13 1971-03-12 PROCEDURE FOR THE PREPARATION OF 7BETA- (D-5-AMINO-5-CARBOXYVALERAMIDO) -3- (CARBAMOYLOXYMETHYL) -7-METHOXY-3-CEPHEM-4-CARBOXYLIC ACID OR SALPER ACALPH

Country Status (19)

Country Link
JP (1) JPS581919B1 (en)
AR (3) AR200370A1 (en)
BE (1) BE764160A (en)
CA (1) CA960169A (en)
CH (5) CH586226A5 (en)
DD (3) DD96254A5 (en)
DE (3) DE2166462B2 (en)
DK (1) DK131639C (en)
FI (1) FI51484C (en)
FR (1) FR2085702B1 (en)
GB (1) GB1321412A (en)
IE (1) IE35110B1 (en)
IL (1) IL36281A (en)
IT (1) IT1045524B (en)
NL (1) NL171285C (en)
NO (1) NO134219C (en)
PH (1) PH12292A (en)
SE (1) SE385713B (en)
YU (1) YU35164B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1040620A (en) * 1972-11-14 1978-10-17 Frank J. Urban 6-alkoxy-6-acylamidopenicillins 7-alkoxy-7-acylamido acetoxycephalosporins and process
US4065356A (en) 1976-02-12 1977-12-27 Merck & Co., Inc. Production of antibiotic FR-02A (efrotomycin) by streptomyces lactamdurans
US4327093A (en) 1978-10-24 1982-04-27 Fujisawa Pharmaceutical Co., Ltd. 3,7-Disubstituted-2 or 3-cephem-4-carboxylic acid compounds
JPS5931517B2 (en) * 1978-12-12 1984-08-02 山之内製薬株式会社 New 7↓-methoxycephalosporin derivative
US4379920A (en) * 1979-10-31 1983-04-12 Glaxo Group Limited Cephalosporins
EP0137365A3 (en) * 1983-09-06 1986-01-15 Takeda Chemical Industries, Ltd. Cephalosporins and their production
EP0160745A3 (en) * 1984-05-07 1986-11-05 Takeda Chemical Industries, Ltd. Cephem compounds and their production
ES2400562T3 (en) 2003-05-28 2013-04-10 Dsm Sinochem Pharmaceuticals Netherlands B.V. Cefem compound

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4945594A (en) * 1972-09-08 1974-05-01

Also Published As

Publication number Publication date
BE764160A (en) 1971-09-13
SE385713B (en) 1976-07-19
NL171285B (en) 1982-10-01
CH586226A5 (en) 1977-03-31
FR2085702B1 (en) 1974-08-23
AR212149A1 (en) 1978-05-31
IE35110L (en) 1971-09-13
DE2109854A1 (en) 1971-09-23
FI51484C (en) 1977-01-10
DD100002A5 (en) 1973-09-05
FR2085702A1 (en) 1971-12-31
DE2166463A1 (en) 1974-05-02
IL36281A (en) 1977-04-29
IL36281A0 (en) 1971-04-28
DD99166A5 (en) 1973-07-20
CH587856A5 (en) 1977-05-13
AR201142A1 (en) 1975-02-14
JPS581919B1 (en) 1983-01-13
DE2109854B2 (en) 1974-09-26
YU35164B (en) 1980-09-25
CH589655A5 (en) 1977-07-15
CH579576A5 (en) 1976-09-15
DE2109854C3 (en) 1975-06-05
NO134219C (en) 1976-09-01
NL171285C (en) 1983-03-01
IT1045524B (en) 1980-05-10
NL7103360A (en) 1971-09-15
IE35110B1 (en) 1975-11-12
FI51484B (en) 1976-09-30
AR200370A1 (en) 1974-11-08
DE2166462A1 (en) 1974-05-09
PH12292A (en) 1978-12-29
DE2166462B2 (en) 1977-01-20
DD96254A5 (en) 1973-03-12
DK131639C (en) 1976-01-12
GB1321412A (en) 1973-06-27
CA960169A (en) 1974-12-31
YU62671A (en) 1979-12-31
NO134219B (en) 1976-05-24
CH587911A5 (en) 1977-05-13

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Legal Events

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PBP Patent lapsed