FI48924C - Menetelmä terapeuttisesti käytettävien 4'-demetyyli-epipodofyllotoksii nin glukosidien valmistamiseksi. - Google Patents
Menetelmä terapeuttisesti käytettävien 4'-demetyyli-epipodofyllotoksii nin glukosidien valmistamiseksi.Info
- Publication number
- FI48924C FI48924C FI690368A FI36869A FI48924C FI 48924 C FI48924 C FI 48924C FI 690368 A FI690368 A FI 690368A FI 36869 A FI36869 A FI 36869A FI 48924 C FI48924 C FI 48924C
- Authority
- FI
- Finland
- Prior art keywords
- demethyl
- preparation
- therapeutically useful
- epipodophyllotoxin glucosides
- epipodophyllotoxin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/54—Preparation of carboxylic acid anhydrides
- C07C51/56—Preparation of carboxylic acid anhydrides from organic acids, their salts, their esters or their halides, e.g. by carboxylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Saccharide Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI239774A FI239774A (fi) | 1968-02-27 | 1974-08-13 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH284568A CH514578A (de) | 1968-02-27 | 1968-02-27 | Verfahren zur Herstellung von Glucosiden |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI48924B FI48924B (fi) | 1974-10-31 |
| FI48924C true FI48924C (fi) | 1975-02-10 |
Family
ID=4242875
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI690368A FI48924C (fi) | 1968-02-27 | 1969-02-06 | Menetelmä terapeuttisesti käytettävien 4'-demetyyli-epipodofyllotoksii nin glukosidien valmistamiseksi. |
Country Status (9)
| Country | Link |
|---|---|
| AT (2) | AT319971B (fi) |
| BR (1) | BR6906655D0 (fi) |
| CA (1) | CA956939A (fi) |
| CH (2) | CH514578A (fi) |
| CS (2) | CS153032B2 (fi) |
| DK (2) | DK123715B (fi) |
| FI (1) | FI48924C (fi) |
| NL (1) | NL166028C (fi) |
| SU (2) | SU406346A3 (fi) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3374317D1 (en) * | 1982-11-26 | 1987-12-10 | Nippon Kayaku Kk | Process for producing 4'-demethyl-epipodophyllotoxin-beta-d-ethylidene-glucoside and acyl-derivative thereof |
| JPS61189230A (ja) * | 1985-02-19 | 1986-08-22 | Nippon Kayaku Co Ltd | エトポシド製剤 |
| IL77334A (en) * | 1985-12-16 | 1991-04-15 | Univ Bar Ilan | Synthesis of 9-epipodophyllotoxin glucoside derivatives and some novel intermediates therefor |
| US4904768A (en) * | 1987-08-04 | 1990-02-27 | Bristol-Myers Company | Epipodophyllotoxin glucoside 4'-phosphate derivatives |
| US4935504A (en) * | 1987-12-18 | 1990-06-19 | Bristol-Myers Company | Epipodophyllotoxin glucoside 4'-acyl derivatives |
| US5036055A (en) * | 1989-06-07 | 1991-07-30 | Bristol-Myers Company | Acylated derivatives of etoposide |
| US5066645A (en) * | 1989-09-01 | 1991-11-19 | Bristol-Myers Company | Epipodophyllotoxin altroside derivatives |
| US5463040A (en) * | 1994-06-28 | 1995-10-31 | Teva Pharmaceutical Industries, Ltd. | Method of preparing etoposide |
| US8173621B2 (en) | 2008-06-11 | 2012-05-08 | Gilead Pharmasset Llc | Nucleoside cyclicphosphates |
| KR20110104074A (ko) | 2008-12-23 | 2011-09-21 | 파마셋 인코포레이티드 | 퓨린 뉴클레오시드의 합성 |
| SG172359A1 (en) | 2008-12-23 | 2011-07-28 | Pharmasset Inc | Nucleoside phosphoramidates |
| CL2009002208A1 (es) | 2008-12-23 | 2010-10-29 | Gilead Pharmasset Llc | Un compuesto (2s)-2-((((2r,3r,4r,5r)-5-(2-amino-6-etoxi-9h-purin-9-il)-4-fluoro-3-hidroxi-4-metiltetrahidrofuran-2-il)metoxi)(hidroxi)fosforilamino)propanoico, inhibidores de la replicacion de arn viral; composicion farmaceutica; y su uso en el tratamiento de infeccion por hepatitis c, virus del nilo occidental, entre otras. |
| KR101715981B1 (ko) | 2010-03-31 | 2017-03-13 | 길리애드 파마셋 엘엘씨 | 뉴클레오사이드 포스포르아미데이트 |
| KR20230042756A (ko) | 2016-03-15 | 2023-03-29 | 오리존 지노믹스 에스.에이. | 고형 종양의 치료에 사용하기 위한 lsd1 억제제의 조합물 |
-
1968
- 1968-02-27 CH CH284568A patent/CH514578A/de not_active IP Right Cessation
-
1969
- 1969-01-31 NL NL6901619.A patent/NL166028C/xx not_active IP Right Cessation
- 1969-02-06 DK DK64169AA patent/DK123715B/da not_active IP Right Cessation
- 1969-02-06 FI FI690368A patent/FI48924C/fi active
- 1969-02-25 CS CS132569A patent/CS153032B2/cs unknown
- 1969-02-25 SU SU1306929A patent/SU406346A3/ru active
- 1969-02-25 AT AT128571A patent/AT319971B/de not_active IP Right Cessation
- 1969-02-25 CS CS526269*A patent/CS153033B2/cs unknown
- 1969-02-25 AT AT188969A patent/AT303270B/de not_active IP Right Cessation
- 1969-02-25 SU SU1832411A patent/SU447886A3/ru active
- 1969-02-25 CA CA043,890A patent/CA956939A/en not_active Expired
- 1969-02-26 BR BR206655/69A patent/BR6906655D0/pt unknown
-
1970
- 1970-10-08 CH CH1489370A patent/CH518927A/de not_active IP Right Cessation
-
1971
- 1971-06-01 DK DK266771AA patent/DK128563B/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CH518927A (de) | 1972-02-15 |
| CS153032B2 (fi) | 1974-02-22 |
| NL166028C (nl) | 1981-06-15 |
| AT319971B (de) | 1975-01-27 |
| SU406346A3 (fi) | 1973-11-05 |
| CA956939A (en) | 1974-10-29 |
| BR6906655D0 (pt) | 1973-01-09 |
| CS153033B2 (fi) | 1974-02-22 |
| NL166028B (nl) | 1981-01-15 |
| FI48924B (fi) | 1974-10-31 |
| DK128563B (da) | 1974-05-27 |
| CH514578A (de) | 1971-10-31 |
| NL6901619A (fi) | 1969-08-29 |
| DK123715B (da) | 1972-07-24 |
| AT303270B (de) | 1972-11-27 |
| SU447886A3 (ru) | 1974-10-25 |
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