FI48924C - Menetelmä terapeuttisesti käytettävien 4'-demetyyli-epipodofyllotoksii nin glukosidien valmistamiseksi. - Google Patents
Menetelmä terapeuttisesti käytettävien 4'-demetyyli-epipodofyllotoksii nin glukosidien valmistamiseksi.Info
- Publication number
- FI48924C FI48924C FI690368A FI36869A FI48924C FI 48924 C FI48924 C FI 48924C FI 690368 A FI690368 A FI 690368A FI 36869 A FI36869 A FI 36869A FI 48924 C FI48924 C FI 48924C
- Authority
- FI
- Finland
- Prior art keywords
- demethyl
- preparation
- therapeutically useful
- epipodophyllotoxin glucosides
- epipodophyllotoxin
- Prior art date
Links
- FOVRGQUEGRCWPD-UHFFFAOYSA-N (5aR)-9t-beta-D-Glucopyranosyloxy-5t-(4-hydroxy-3,5-dimethoxy-phenyl)-(5ar,8at)-5,8,8a,9-tetrahydro-5aH-furo[3',4';6,7]naphtho[2,3-d][1,3]dioxol-6-on Natural products COC1=C(O)C(OC)=CC(C2C3=CC=4OCOC=4C=C3C(OC3C(C(O)C(O)C(CO)O3)O)C3C2C(OC3)=O)=C1 FOVRGQUEGRCWPD-UHFFFAOYSA-N 0.000 title 1
- -1 4'-demethyl-epipodophyllotoxin glucosides Chemical class 0.000 title 1
- 229930182478 glucoside Natural products 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/54—Preparation of carboxylic acid anhydrides
- C07C51/56—Preparation of carboxylic acid anhydrides from organic acids, their salts, their esters or their halides, e.g. by carboxylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Saccharide Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI2397/74A FI239774A7 (da) | 1968-02-27 | 1974-08-13 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH284568A CH514578A (de) | 1968-02-27 | 1968-02-27 | Verfahren zur Herstellung von Glucosiden |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI48924B FI48924B (da) | 1974-10-31 |
| FI48924C true FI48924C (fi) | 1975-02-10 |
Family
ID=4242875
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI690368A FI48924C (fi) | 1968-02-27 | 1969-02-06 | Menetelmä terapeuttisesti käytettävien 4'-demetyyli-epipodofyllotoksii nin glukosidien valmistamiseksi. |
Country Status (9)
| Country | Link |
|---|---|
| AT (2) | AT303270B (da) |
| BR (1) | BR6906655D0 (da) |
| CA (1) | CA956939A (da) |
| CH (2) | CH514578A (da) |
| CS (2) | CS153032B2 (da) |
| DK (2) | DK123715B (da) |
| FI (1) | FI48924C (da) |
| NL (1) | NL166028C (da) |
| SU (2) | SU447886A3 (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0111058B1 (en) * | 1982-11-26 | 1987-11-04 | Nippon Kayaku Kabushiki Kaisha | Process for producing 4'-demethyl-epipodophyllotoxin-beta-d-ethylidene-glucoside and acyl-derivative thereof |
| JPS61189230A (ja) * | 1985-02-19 | 1986-08-22 | Nippon Kayaku Co Ltd | エトポシド製剤 |
| IL77334A (en) * | 1985-12-16 | 1991-04-15 | Univ Bar Ilan | Synthesis of 9-epipodophyllotoxin glucoside derivatives and some novel intermediates therefor |
| US4904768A (en) * | 1987-08-04 | 1990-02-27 | Bristol-Myers Company | Epipodophyllotoxin glucoside 4'-phosphate derivatives |
| US4935504A (en) * | 1987-12-18 | 1990-06-19 | Bristol-Myers Company | Epipodophyllotoxin glucoside 4'-acyl derivatives |
| US5036055A (en) * | 1989-06-07 | 1991-07-30 | Bristol-Myers Company | Acylated derivatives of etoposide |
| US5066645A (en) * | 1989-09-01 | 1991-11-19 | Bristol-Myers Company | Epipodophyllotoxin altroside derivatives |
| US5463040A (en) * | 1994-06-28 | 1995-10-31 | Teva Pharmaceutical Industries, Ltd. | Method of preparing etoposide |
| US8173621B2 (en) | 2008-06-11 | 2012-05-08 | Gilead Pharmasset Llc | Nucleoside cyclicphosphates |
| MX2011006891A (es) | 2008-12-23 | 2011-10-06 | Pharmasset Inc | Fosforamidatos de nucleosidos. |
| US8716263B2 (en) | 2008-12-23 | 2014-05-06 | Gilead Pharmasset Llc | Synthesis of purine nucleosides |
| AU2017233898B2 (en) | 2016-03-15 | 2022-12-15 | Oryzon Genomics, S.A. | Combinations of LSD1 inhibitors for use in the treatment of solid tumors |
-
1968
- 1968-02-27 CH CH284568A patent/CH514578A/de not_active IP Right Cessation
-
1969
- 1969-01-31 NL NL6901619.A patent/NL166028C/xx not_active IP Right Cessation
- 1969-02-06 DK DK64169AA patent/DK123715B/da not_active IP Right Cessation
- 1969-02-06 FI FI690368A patent/FI48924C/fi active
- 1969-02-25 SU SU1832411A patent/SU447886A3/ru active
- 1969-02-25 SU SU1306929A patent/SU406346A3/ru active
- 1969-02-25 CS CS132569A patent/CS153032B2/cs unknown
- 1969-02-25 AT AT188969A patent/AT303270B/de not_active IP Right Cessation
- 1969-02-25 CS CS526269*A patent/CS153033B2/cs unknown
- 1969-02-25 CA CA043,890A patent/CA956939A/en not_active Expired
- 1969-02-25 AT AT128571A patent/AT319971B/de not_active IP Right Cessation
- 1969-02-26 BR BR206655/69A patent/BR6906655D0/pt unknown
-
1970
- 1970-10-08 CH CH1489370A patent/CH518927A/de not_active IP Right Cessation
-
1971
- 1971-06-01 DK DK266771AA patent/DK128563B/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NL166028C (nl) | 1981-06-15 |
| AT319971B (de) | 1975-01-27 |
| SU406346A3 (da) | 1973-11-05 |
| DK128563B (da) | 1974-05-27 |
| NL166028B (nl) | 1981-01-15 |
| CH514578A (de) | 1971-10-31 |
| DK123715B (da) | 1972-07-24 |
| SU447886A3 (ru) | 1974-10-25 |
| NL6901619A (da) | 1969-08-29 |
| FI48924B (da) | 1974-10-31 |
| CS153032B2 (da) | 1974-02-22 |
| CA956939A (en) | 1974-10-29 |
| AT303270B (de) | 1972-11-27 |
| CH518927A (de) | 1972-02-15 |
| CS153033B2 (da) | 1974-02-22 |
| BR6906655D0 (pt) | 1973-01-09 |
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