FI47354C - Menetelmä 6,7-metyleeni-20-spiroks-4-eeni-3-onien valmistamiseksi, jot ka ovat aldosteronin antagonisteja. - Google Patents

Menetelmä 6,7-metyleeni-20-spiroks-4-eeni-3-onien valmistamiseksi, jot ka ovat aldosteronin antagonisteja.

Info

Publication number
FI47354C
FI47354C FI690718A FI71869A FI47354C FI 47354 C FI47354 C FI 47354C FI 690718 A FI690718 A FI 690718A FI 71869 A FI71869 A FI 71869A FI 47354 C FI47354 C FI 47354C
Authority
FI
Finland
Prior art keywords
spirox
aldosterone
antagonists
methylene
ones
Prior art date
Application number
FI690718A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI47354B (enrdf_load_stackoverflow
Inventor
Arth
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of FI47354B publication Critical patent/FI47354B/fi
Publication of FI47354C publication Critical patent/FI47354C/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • E—FIXED CONSTRUCTIONS
    • E05—LOCKS; KEYS; WINDOW OR DOOR FITTINGS; SAFES
    • E05G—SAFES OR STRONG-ROOMS FOR VALUABLES; BANK PROTECTION DEVICES; SAFETY TRANSACTION PARTITIONS
    • E05G1/00—Safes or strong-rooms for valuables
    • E05G1/02—Details
    • E05G1/024—Wall or panel structure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
FI690718A 1968-03-22 1969-03-11 Menetelmä 6,7-metyleeni-20-spiroks-4-eeni-3-onien valmistamiseksi, jot ka ovat aldosteronin antagonisteja. FI47354C (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71516068A 1968-03-22 1968-03-22

Publications (2)

Publication Number Publication Date
FI47354B FI47354B (enrdf_load_stackoverflow) 1973-07-31
FI47354C true FI47354C (fi) 1973-11-12

Family

ID=24872890

Family Applications (1)

Application Number Title Priority Date Filing Date
FI690718A FI47354C (fi) 1968-03-22 1969-03-11 Menetelmä 6,7-metyleeni-20-spiroks-4-eeni-3-onien valmistamiseksi, jot ka ovat aldosteronin antagonisteja.

Country Status (14)

Country Link
AT (1) AT297948B (enrdf_load_stackoverflow)
BE (1) BE730163A (enrdf_load_stackoverflow)
BR (1) BR6907426D0 (enrdf_load_stackoverflow)
CH (1) CH525876A (enrdf_load_stackoverflow)
DK (1) DK123353B (enrdf_load_stackoverflow)
FI (1) FI47354C (enrdf_load_stackoverflow)
FR (1) FR2004562A1 (enrdf_load_stackoverflow)
GB (1) GB1235768A (enrdf_load_stackoverflow)
IE (1) IE33205B1 (enrdf_load_stackoverflow)
IL (1) IL31769A (enrdf_load_stackoverflow)
NL (1) NL166267C (enrdf_load_stackoverflow)
NO (1) NO131175C (enrdf_load_stackoverflow)
SE (1) SE351636B (enrdf_load_stackoverflow)
YU (1) YU34303B (enrdf_load_stackoverflow)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE792624A (fr) * 1972-05-22 1973-06-12 Merck & Co Inc Composes inhibiteurs de l'aldosterone et leur obtention
DE2652761C2 (de) * 1976-11-16 1985-11-21 Schering AG, 1000 Berlin und 4709 Bergkamen 15,16-Methylen-Spirolactone, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
AT351191B (de) * 1976-12-20 1979-07-10 Hoffmann La Roche Verfahren zur herstellung von neuen d-homo- steroiden
DE3222265A1 (de) * 1982-06-09 1983-12-15 Schering AG, 1000 Berlin und 4709 Bergkamen 6ss.7ss-methylen-17(alpha)-pregn-4-en-21.17-carbolactone, verfahren zu ihrer herstellung und verwendung als arzneimittel
JPS59139400A (ja) * 1983-01-31 1984-08-10 Shionogi & Co Ltd 抗アルドステロン活性ステロイド誘導体

Also Published As

Publication number Publication date
BR6907426D0 (pt) 1973-05-31
NO131175B (enrdf_load_stackoverflow) 1975-01-06
DK123353B (da) 1972-06-12
FR2004562A1 (enrdf_load_stackoverflow) 1969-11-28
DE1914507A1 (de) 1969-10-09
NO131175C (enrdf_load_stackoverflow) 1975-04-16
NL166267B (nl) 1981-02-16
CH525876A (de) 1972-07-31
IE33205B1 (en) 1974-04-17
IE33205L (en) 1969-09-22
NL166267C (nl) 1981-07-15
BE730163A (enrdf_load_stackoverflow) 1969-09-22
IL31769A (en) 1973-08-29
NL6903322A (enrdf_load_stackoverflow) 1969-09-24
IL31769A0 (en) 1969-05-28
SE351636B (enrdf_load_stackoverflow) 1972-12-04
GB1235768A (en) 1971-06-16
AT297948B (de) 1972-04-10
YU58169A (en) 1978-10-31
FI47354B (enrdf_load_stackoverflow) 1973-07-31
YU34303B (en) 1979-04-30

Similar Documents

Publication Publication Date Title
FI51347C (fi) Menetelmä 1-substituoitujen-3- ja -4-aroyylipiperidiinien valmistamise ksi.
NL140263B (nl) Werkwijze voor de bereiding van als lijmen geschikte polyamiden.
FI52574C (fi) Menetelmä farmakologisesti arvokkaiden substituoitujen N-allyyli-2-fen yyliamino-imidatsoliinien-(2) valmistamiseksi.
NL162083C (nl) Werkwijze voor de bereiding van 17alfa-mono-esters van 11beta,17alfa,21-trihydroxy-20-oxosteroiden.
NL144588B (nl) Werkwijze ter bereiding van n-methylnitroanilinen.
AR199966A1 (es) Un intermediario del alquil inferior fosfonato
FI47572C (fi) Menetelmä 19-norandrost-4-eeni-3,17-dionien valmistamiseksi.
FI50334C (fi) Menetelmä 1-hydroksi-2pyridonien valmistamiseksi.
FI47354C (fi) Menetelmä 6,7-metyleeni-20-spiroks-4-eeni-3-onien valmistamiseksi, jot ka ovat aldosteronin antagonisteja.
FI51700C (fi) Menetelmä rauhoittavina lääkeaineina käyttökelpoisten 6-fenyyli-4H-s-t riatsolo-(1,5a)(1,4)-bentsodiatsepiinien valmistamiseksi.
FI47575C (fi) Analogiamenetelmä evomonosidi-johdannaisten valmistamiseksi.
FI52216C (fi) Menetelmä gamma-piperidinobutyrofenonijohdannaisten valmistamiseksi.
NL143271B (nl) Werkwijze ter bereiding van reukstofcomposities.
NL143932B (nl) Werkwijze ter bereiding van pyrimidopyridazinederivaten.
NL158771B (nl) Werkwijze voor het kraken van 4,4-dimethyl m-dioxan tot isopreen.
FI46844C (fi) Menetelmä 9alfa,21,21-triklooristeroidien valmistamiseksi.
DK129524B (da) Fremgangsmåde til fremstilling af di-(3,5-dioxopiperazin-1-yl)-alkanderivater.
NL161163B (nl) Werkwijze voor de bereiding van hydroxyalkylaminoalkaan- fosfonaten.
FI47763C (fi) Menetelmä uusien neriifoliini-johdannaisten valmistamiseksi.
NL153865B (nl) Werkwijze voor de continue bereiding van caprolactam.
FI47349C (fi) Menetelmä 17alfa-propadienyyli-17beta-hydroksi-steroidien valmistamise ksi.
FI50710C (fi) Menetelmä 1,4-bentsodiatsepiinien valmistamiseksi.
FI51814C (fi) Menetelmä alfa-karboksibentsyylipenisiliinin kielteisen alkalimetallis uolojen valmistamiseksi.
FI46724C (fi) Menetelmä 1,18-dimetyyli-5alfa-H-androst-1-eenijohdannaisten valmistam iseksi.
FI45046C (fi) Menetelmä rauhoittavina aineina vaikuttavien fentiatsiinien 3,8-diatsa bisyklo-oktaani-johdannaisten valmistamiseksi.