IL31769A - Spiroxenone derivatives as aldosterone antagonists - Google Patents

Spiroxenone derivatives as aldosterone antagonists

Info

Publication number
IL31769A
IL31769A IL31769A IL3176969A IL31769A IL 31769 A IL31769 A IL 31769A IL 31769 A IL31769 A IL 31769A IL 3176969 A IL3176969 A IL 3176969A IL 31769 A IL31769 A IL 31769A
Authority
IL
Israel
Prior art keywords
spiroxenone
derivatives
aldosterone antagonists
aldosterone
antagonists
Prior art date
Application number
IL31769A
Other languages
English (en)
Other versions
IL31769A0 (en
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of IL31769A0 publication Critical patent/IL31769A0/xx
Publication of IL31769A publication Critical patent/IL31769A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • EFIXED CONSTRUCTIONS
    • E05LOCKS; KEYS; WINDOW OR DOOR FITTINGS; SAFES
    • E05GSAFES OR STRONG-ROOMS FOR VALUABLES; BANK PROTECTION DEVICES; SAFETY TRANSACTION PARTITIONS
    • E05G1/00Safes or strong-rooms for valuables
    • E05G1/02Details
    • E05G1/024Wall or panel structure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
IL31769A 1968-03-22 1969-03-10 Spiroxenone derivatives as aldosterone antagonists IL31769A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71516068A 1968-03-22 1968-03-22

Publications (2)

Publication Number Publication Date
IL31769A0 IL31769A0 (en) 1969-05-28
IL31769A true IL31769A (en) 1973-08-29

Family

ID=24872890

Family Applications (1)

Application Number Title Priority Date Filing Date
IL31769A IL31769A (en) 1968-03-22 1969-03-10 Spiroxenone derivatives as aldosterone antagonists

Country Status (14)

Country Link
AT (1) AT297948B (xx)
BE (1) BE730163A (xx)
BR (1) BR6907426D0 (xx)
CH (1) CH525876A (xx)
DK (1) DK123353B (xx)
FI (1) FI47354C (xx)
FR (1) FR2004562A1 (xx)
GB (1) GB1235768A (xx)
IE (1) IE33205B1 (xx)
IL (1) IL31769A (xx)
NL (1) NL166267C (xx)
NO (1) NO131175C (xx)
SE (1) SE351636B (xx)
YU (1) YU34303B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE792624A (fr) * 1972-05-22 1973-06-12 Merck & Co Inc Composes inhibiteurs de l'aldosterone et leur obtention
DE2652761C2 (de) * 1976-11-16 1985-11-21 Schering AG, 1000 Berlin und 4709 Bergkamen 15,16-Methylen-Spirolactone, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
AT351191B (de) * 1976-12-20 1979-07-10 Hoffmann La Roche Verfahren zur herstellung von neuen d-homo- steroiden
DE3222265A1 (de) * 1982-06-09 1983-12-15 Schering AG, 1000 Berlin und 4709 Bergkamen 6ss.7ss-methylen-17(alpha)-pregn-4-en-21.17-carbolactone, verfahren zu ihrer herstellung und verwendung als arzneimittel
JPS59139400A (ja) * 1983-01-31 1984-08-10 Shionogi & Co Ltd 抗アルドステロン活性ステロイド誘導体

Also Published As

Publication number Publication date
NL6903322A (xx) 1969-09-24
YU34303B (en) 1979-04-30
GB1235768A (en) 1971-06-16
IL31769A0 (en) 1969-05-28
SE351636B (xx) 1972-12-04
FR2004562A1 (xx) 1969-11-28
NO131175C (xx) 1975-04-16
CH525876A (de) 1972-07-31
AT297948B (de) 1972-04-10
DK123353B (da) 1972-06-12
BR6907426D0 (pt) 1973-05-31
DE1914507A1 (de) 1969-10-09
IE33205B1 (en) 1974-04-17
NL166267B (nl) 1981-02-16
YU58169A (en) 1978-10-31
IE33205L (en) 1969-09-22
NL166267C (nl) 1981-07-15
NO131175B (xx) 1975-01-06
BE730163A (xx) 1969-09-22
FI47354C (fi) 1973-11-12
FI47354B (xx) 1973-07-31

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