FI20105633A0 - Parannettu menetelmä proteiinien tuottamiseksi - Google Patents

Parannettu menetelmä proteiinien tuottamiseksi

Info

Publication number
FI20105633A0
FI20105633A0 FI20105633A FI20105633A FI20105633A0 FI 20105633 A0 FI20105633 A0 FI 20105633A0 FI 20105633 A FI20105633 A FI 20105633A FI 20105633 A FI20105633 A FI 20105633A FI 20105633 A0 FI20105633 A0 FI 20105633A0
Authority
FI
Finland
Prior art keywords
protein production
improved protein
improved
production
protein
Prior art date
Application number
FI20105633A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Inventor
Tiina Pakula
Markku Saloheimo
Mari Haekkinen
Ann Westerholm-Parviainen
Merja Penttilae
Marika Vitikainen
Original Assignee
Valtion Teknillinen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valtion Teknillinen filed Critical Valtion Teknillinen
Priority to FI20105633A priority Critical patent/FI20105633A0/fi
Publication of FI20105633A0 publication Critical patent/FI20105633A0/fi
Priority to BR112012030919A priority patent/BR112012030919A2/pt
Priority to CN201180035960.6A priority patent/CN103154249B/zh
Priority to ES13199346.1T priority patent/ES2659946T3/es
Priority to US13/701,919 priority patent/US9487791B2/en
Priority to DK11726859.9T priority patent/DK2576793T3/en
Priority to DK13199346.1T priority patent/DK2733210T3/en
Priority to CA2801599A priority patent/CA2801599C/en
Priority to MX2012014138A priority patent/MX346117B/es
Priority to EP13199346.1A priority patent/EP2733210B1/en
Priority to PCT/FI2011/050495 priority patent/WO2011151513A1/en
Priority to EP11726859.9A priority patent/EP2576793B1/en
Priority to US14/712,458 priority patent/US20150307862A1/en
Priority to US14/977,496 priority patent/US9695430B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2437—Cellulases (3.2.1.4; 3.2.1.74; 3.2.1.91; 3.2.1.150)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/244—Endo-1,3(4)-beta-glucanase (3.2.1.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2445—Beta-glucosidase (3.2.1.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2477—Hemicellulases not provided in a preceding group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2477—Hemicellulases not provided in a preceding group
    • C12N9/248—Xylanases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01004—Cellulase (3.2.1.4), i.e. endo-1,4-beta-glucanase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01006—Endo-1,3(4)-beta-glucanase (3.2.1.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01021—Beta-glucosidase (3.2.1.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01091—Cellulose 1,4-beta-cellobiosidase (3.2.1.91)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI20105633A 2010-06-04 2010-06-04 Parannettu menetelmä proteiinien tuottamiseksi FI20105633A0 (fi)

Priority Applications (14)

Application Number Priority Date Filing Date Title
FI20105633A FI20105633A0 (fi) 2010-06-04 2010-06-04 Parannettu menetelmä proteiinien tuottamiseksi
EP11726859.9A EP2576793B1 (en) 2010-06-04 2011-05-30 Method for improved protein production in filamentous fungi
DK13199346.1T DK2733210T3 (en) 2010-06-04 2011-05-30 Process for improved protein production
CN201180035960.6A CN103154249B (zh) 2010-06-04 2011-05-30 用于在丝状真菌中改进的蛋白质生产的方法
ES13199346.1T ES2659946T3 (es) 2010-06-04 2011-05-30 Método para la producción mejorada de proteínas en hongos filamentosos
US13/701,919 US9487791B2 (en) 2010-06-04 2011-05-30 Method for improved protein production in filamentous fungi
DK11726859.9T DK2576793T3 (en) 2010-06-04 2011-05-30 PROCEDURE FOR IMPROVED PROTEIN PRODUCTION IN FILAMENT'S FUNGI
BR112012030919A BR112012030919A2 (pt) 2010-06-04 2011-05-30 método para aperfeiçoada produção de proteína em fungos filamentosos
CA2801599A CA2801599C (en) 2010-06-04 2011-05-30 Method for improved protein production in filamentous fungi
MX2012014138A MX346117B (es) 2010-06-04 2011-05-30 Metodo para produccion mejorada de proteinas en hongo filamentoso.
EP13199346.1A EP2733210B1 (en) 2010-06-04 2011-05-30 Method for improved protein production in filamentous fungi
PCT/FI2011/050495 WO2011151513A1 (en) 2010-06-04 2011-05-30 Method for improved protein production in filamentous fungi
US14/712,458 US20150307862A1 (en) 2010-06-04 2015-05-14 Method for improved protein production in filamentous fungi
US14/977,496 US9695430B2 (en) 2010-06-04 2015-12-21 Method for improved protein production in filamentous fungi

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI20105633A FI20105633A0 (fi) 2010-06-04 2010-06-04 Parannettu menetelmä proteiinien tuottamiseksi

Publications (1)

Publication Number Publication Date
FI20105633A0 true FI20105633A0 (fi) 2010-06-04

Family

ID=42308090

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20105633A FI20105633A0 (fi) 2010-06-04 2010-06-04 Parannettu menetelmä proteiinien tuottamiseksi

Country Status (10)

Country Link
US (3) US9487791B2 (pt)
EP (2) EP2576793B1 (pt)
CN (1) CN103154249B (pt)
BR (1) BR112012030919A2 (pt)
CA (1) CA2801599C (pt)
DK (2) DK2733210T3 (pt)
ES (1) ES2659946T3 (pt)
FI (1) FI20105633A0 (pt)
MX (1) MX346117B (pt)
WO (1) WO2011151513A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104087568A (zh) * 2014-06-11 2014-10-08 华南理工大学 一种制浆造纸漂白预处理用半纤维素酶的制备和应用
CN106190874B (zh) * 2015-05-06 2020-06-26 中国科学院天津工业生物技术研究所 一种强化丝状真菌蛋白质生产的方法
CN106119137B (zh) * 2015-05-06 2020-06-26 中国科学院天津工业生物技术研究所 一种改善丝状真菌蛋白分泌能力的方法
WO2017177289A1 (en) 2016-04-15 2017-10-19 Vtt International Oy Process for conversion of biomass into fermentable sugars with integrated enzyme
CN112105740A (zh) * 2018-02-23 2020-12-18 诺维信公司 真菌宿主中的长链非编码rna表达
EP3981882A1 (en) * 2020-10-08 2022-04-13 Clariant Produkte (Deutschland) GmbH Process for the production of a filamentous fungus whole broth enzyme composition with low viscosity
WO2023003683A2 (en) 2021-07-19 2023-01-26 Danisco Us Inc. Compositions and methods for enhanced protein production in fungal cells
WO2023102315A1 (en) 2021-12-01 2023-06-08 Danisco Us Inc. Compositions and methods for enhanced protein production in fungal cells

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1266018T3 (da) * 2000-03-24 2008-09-01 Genencor Int Fremstilling af udskilte proteiner af rekombinante, eukaryotiske celler
WO2008027472A2 (en) * 2006-08-29 2008-03-06 Danisco Us, Inc., Genencor Division Compositions and methods for improved protein production
WO2008156605A1 (en) * 2007-06-15 2008-12-24 Danisco Us, Inc., Genencor Division Selection of useful fungal strains

Also Published As

Publication number Publication date
DK2576793T3 (en) 2017-07-10
US20160108409A1 (en) 2016-04-21
EP2576793B1 (en) 2017-03-15
US9487791B2 (en) 2016-11-08
EP2576793A1 (en) 2013-04-10
US9695430B2 (en) 2017-07-04
US20150307862A1 (en) 2015-10-29
WO2011151513A1 (en) 2011-12-08
CN103154249A (zh) 2013-06-12
EP2733210B1 (en) 2017-12-06
BR112012030919A2 (pt) 2018-08-28
US20130084604A1 (en) 2013-04-04
CA2801599C (en) 2019-01-15
MX2012014138A (es) 2013-05-20
DK2733210T3 (en) 2018-03-12
MX346117B (es) 2017-03-08
CA2801599A1 (en) 2011-12-08
ES2659946T3 (es) 2018-03-20
CN103154249B (zh) 2015-12-02
EP2733210A1 (en) 2014-05-21

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