FI20021626A - Immunoassay reagent and method for the detection of hepatitis C virus (HCV) antibodies - Google Patents

Immunoassay reagent and method for the detection of hepatitis C virus (HCV) antibodies Download PDF

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Publication number
FI20021626A
FI20021626A FI20021626A FI20021626A FI20021626A FI 20021626 A FI20021626 A FI 20021626A FI 20021626 A FI20021626 A FI 20021626A FI 20021626 A FI20021626 A FI 20021626A FI 20021626 A FI20021626 A FI 20021626A
Authority
FI
Finland
Prior art keywords
hcv
hepatitis
antibodies
virus
detection
Prior art date
Application number
FI20021626A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI111645B (en
Inventor
David Y Chien
William Rutter
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of FI20021626A publication Critical patent/FI20021626A/en
Application granted granted Critical
Publication of FI111645B publication Critical patent/FI111645B/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Abstract

We have discovered epitopes of the HCV viral proteins which are immunoreactive with immune serum. The epitopes are useful in immunodiagnostic assays and as immunogens.
FI20021626A 1991-06-24 2002-09-11 Reagents for immunoassay and method for detection of hepatitis C virus (HCV) antibodies FI111645B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US72248991A 1991-06-24 1991-06-24
US72248991 1991-06-24
PCT/US1992/005388 WO1993000365A2 (en) 1991-06-24 1992-06-24 Hepatitis c virus (hcv) polypeptides
US9205388 1992-06-24

Publications (2)

Publication Number Publication Date
FI20021626A true FI20021626A (en) 2002-09-11
FI111645B FI111645B (en) 2003-08-29

Family

ID=24902063

Family Applications (2)

Application Number Title Priority Date Filing Date
FI935808A FI110099B (en) 1991-06-24 1993-12-22 A method for producing hepatitis C virus (HCV) polypeptides
FI20021626A FI111645B (en) 1991-06-24 2002-09-11 Reagents for immunoassay and method for detection of hepatitis C virus (HCV) antibodies

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI935808A FI110099B (en) 1991-06-24 1993-12-22 A method for producing hepatitis C virus (HCV) polypeptides

Country Status (16)

Country Link
US (2) US6346375B1 (en)
EP (1) EP0591431B1 (en)
JP (9) JP3516681B2 (en)
KR (1) KR0185426B1 (en)
AT (1) ATE229543T1 (en)
BG (1) BG61843B1 (en)
CA (1) CA2110058C (en)
DE (1) DE69232871T2 (en)
ES (1) ES2188583T3 (en)
FI (2) FI110099B (en)
HU (1) HU227547B1 (en)
NO (1) NO309528B1 (en)
RO (1) RO117329B1 (en)
RU (1) RU2148587C1 (en)
UA (1) UA40572C2 (en)
WO (1) WO1993000365A2 (en)

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Also Published As

Publication number Publication date
RU2148587C1 (en) 2000-05-10
CA2110058C (en) 2001-09-25
AU671594B2 (en) 1996-09-05
JP2004115533A (en) 2004-04-15
JP2007131629A (en) 2007-05-31
JP3514680B2 (en) 2004-03-31
KR0185426B1 (en) 1999-04-01
FI935808A (en) 1994-02-21
JP4456596B2 (en) 2010-04-28
RO117329B1 (en) 2002-01-30
NO934542D0 (en) 1993-12-10
HU227547B1 (en) 2011-08-29
JP3514751B2 (en) 2004-03-31
DE69232871T2 (en) 2003-05-08
US6150087A (en) 2000-11-21
EP0591431A1 (en) 1994-04-13
WO1993000365A2 (en) 1993-01-07
FI110099B (en) 2002-11-29
EP0591431B1 (en) 2002-12-11
ES2188583T3 (en) 2003-07-01
NO309528B1 (en) 2001-02-12
DE69232871D1 (en) 2003-01-30
FI111645B (en) 2003-08-29
JP2000139485A (en) 2000-05-23
JPH06508837A (en) 1994-10-06
JP3926817B2 (en) 2007-06-06
BG98332A (en) 1995-02-28
JP2005053920A (en) 2005-03-03
JP2007077168A (en) 2007-03-29
WO1993000365A3 (en) 1993-04-29
HU9303703D0 (en) 1994-04-28
AU2305392A (en) 1993-01-25
JP2003277396A (en) 2003-10-02
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JP2008001716A (en) 2008-01-10
US6346375B1 (en) 2002-02-12
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UA40572C2 (en) 2001-08-15
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BG61843B1 (en) 1998-07-31
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