FI20000635A0 - COMT-inhibiittoreiden käyttö analgeettina - Google Patents

COMT-inhibiittoreiden käyttö analgeettina

Info

Publication number
FI20000635A0
FI20000635A0 FI20000635A FI20000635A FI20000635A0 FI 20000635 A0 FI20000635 A0 FI 20000635A0 FI 20000635 A FI20000635 A FI 20000635A FI 20000635 A FI20000635 A FI 20000635A FI 20000635 A0 FI20000635 A0 FI 20000635A0
Authority
FI
Finland
Prior art keywords
analgesic
comt inhibitors
comt
inhibitors
pain
Prior art date
Application number
FI20000635A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Inventor
Paeivi Aho
Inge-Britt Linden
Original Assignee
Orion Yhtymae Oyj
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtymae Oyj filed Critical Orion Yhtymae Oyj
Priority to FI20000635A priority Critical patent/FI20000635A0/fi
Publication of FI20000635A0 publication Critical patent/FI20000635A0/fi
Priority to EP01919513A priority patent/EP1263425B1/fr
Priority to PCT/FI2001/000265 priority patent/WO2001068083A1/fr
Priority to JP2001566647A priority patent/JP4874489B2/ja
Priority to AU2001246600A priority patent/AU2001246600A1/en
Priority to DE60101559T priority patent/DE60101559T2/de
Priority to AT01919513T priority patent/ATE256461T1/de
Priority to CA002403352A priority patent/CA2403352C/fr
Priority to US10/221,497 priority patent/US6723754B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI20000635A 2000-03-17 2000-03-17 COMT-inhibiittoreiden käyttö analgeettina FI20000635A0 (fi)

Priority Applications (9)

Application Number Priority Date Filing Date Title
FI20000635A FI20000635A0 (fi) 2000-03-17 2000-03-17 COMT-inhibiittoreiden käyttö analgeettina
EP01919513A EP1263425B1 (fr) 2000-03-17 2001-03-16 Utilisation d'inhibiteurs de la comt comme analgesiques
PCT/FI2001/000265 WO2001068083A1 (fr) 2000-03-17 2001-03-16 Utilisation d'inhibiteurs de catechine-o-methyle transferase (comt)
JP2001566647A JP4874489B2 (ja) 2000-03-17 2001-03-16 Ｃｏｍｔ阻害剤の鎮痛剤としての用途
AU2001246600A AU2001246600A1 (en) 2000-03-17 2001-03-16 Use of comt inhibitors as analgesics
DE60101559T DE60101559T2 (de) 2000-03-17 2001-03-16 Benutzung von comt-inhibitoren als analgetika
AT01919513T ATE256461T1 (de) 2000-03-17 2001-03-16 Benutzung von comt-inhibitoren als analgetika
CA002403352A CA2403352C (fr) 2000-03-17 2001-03-16 Utilisation d'inhibiteurs de catechine-o-methyle transferase (comt)
US10/221,497 US6723754B2 (en) 2000-03-17 2001-03-16 Use of COMT inhibitors as analgesics

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI20000635A FI20000635A0 (fi) 2000-03-17 2000-03-17 COMT-inhibiittoreiden käyttö analgeettina

Publications (1)

Publication Number Publication Date
FI20000635A0 true FI20000635A0 (fi) 2000-03-17

Family

ID=8557970

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20000635A FI20000635A0 (fi) 2000-03-17 2000-03-17 COMT-inhibiittoreiden käyttö analgeettina

Country Status (9)

Country Link
US (1) US6723754B2 (fr)
EP (1) EP1263425B1 (fr)
JP (1) JP4874489B2 (fr)
AT (1) ATE256461T1 (fr)
AU (1) AU2001246600A1 (fr)
CA (1) CA2403352C (fr)
DE (1) DE60101559T2 (fr)
FI (1) FI20000635A0 (fr)
WO (1) WO2001068083A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2579574A1 (fr) * 2004-07-23 2007-01-04 The University Of North Carolina At Chapel Hill Procedes et materiaux pour determiner la sensibilite a la douleur et prevoir et traiter des troubles apparentes
MY148644A (en) * 2005-07-18 2013-05-15 Orion Corp New pharmaceutical compounds
CA2616377C (fr) 2005-07-26 2014-04-01 David Alexander Learmonth Derives de nitrocatechol utilises en tant qu'inhibiteurs comt
EP1845097A1 (fr) 2006-04-10 2007-10-17 Portela & Ca., S.A. Derives de oxadiazole en tant qu' inhibiteurs de l'enzyme COMT
CA2572004A1 (fr) * 2006-12-08 2008-06-08 Bernard Charles Sherman Comprimes renfermant de l'entacapone et de la crospovidone
MX2009008051A (es) 2007-01-31 2009-08-12 Bial Portela & Ca Sa Regimen posologico para inhibidores de comt.
MX2010009610A (es) 2008-03-17 2010-09-30 Bial Portela & Ca Sa Formas de cristal de 5-[3-(2,5-dicloro-4,6-dimetil-1-oxi-piridin-3 -il)-[1,2,4]oxadiazol-5-il]-3-nitrobenceno-1,2-diol.
EP2413912B1 (fr) 2009-04-01 2019-03-13 Bial-Portela & CA, S.A. Préparations pharmaceutiques comprenant des dérivés de nitrocatéchol et leurs procédés de fabrication
US20140045900A1 (en) 2011-02-11 2014-02-13 Bial-Portela & Ca, S.A. Administration regime for nitrocatechols
JP6456143B2 (ja) 2011-12-13 2019-01-23 ノヴィファーマ，エス．アー． カテコール−ｏ−メチル転移酵素阻害剤を調製するための中間体として有用な化学的化合物
TWI638802B (zh) 2012-05-24 2018-10-21 芬蘭商奧利安公司 兒茶酚ｏ－甲基轉移酶活性抑制化合物
WO2016083863A1 (fr) 2014-11-28 2016-06-02 Bial - Portela & Ca, S.A. Médicaments destinés au ralentissement de la progresssion de la maladie de parkinson
WO2020020969A1 (fr) 2018-07-25 2020-01-30 Orion Corporation Solvates de 4,5-dihydroxy-2-(4-méthylbenzyl) isophthalonitrile et leurs formes cristallines
WO2020094928A1 (fr) 2018-11-09 2020-05-14 Orion Corporation Procédé de préparation de 4,5-dihydroxy-2-(4-méthylbenzyl)isophtalonitrile
WO2022158991A1 (fr) 2021-01-20 2022-07-28 Bial-Portela & Ca., S.A. Traitement de la douleur associée à la maladie de parkinson avec de l'opicapone en combinaison avec la lévodopa

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB898879A (en) 1959-10-16 1962-06-14 Smith & Nephew Hydrazine derivatives
DK175069B1 (da) * 1986-03-11 2004-05-24 Hoffmann La Roche Pyrocatecholderivater
US5236952A (en) * 1986-03-11 1993-08-17 Hoffmann-La Roche Inc. Catechol derivatives
US5283352A (en) * 1986-11-28 1994-02-01 Orion-Yhtyma Oy Pharmacologically active compounds, methods for the preparation thereof and compositions containing the same
YU213587A (en) * 1986-11-28 1989-06-30 Orion Yhtymae Oy Process for obtaining new pharmacologic active cateholic derivatives
FI864875A0 (fi) 1986-11-28 1986-11-28 Orion Yhtymae Oy Nya farmakologiskt aktiva foereningar, dessa innehaollande kompositioner samt foerfarande och mellanprodukter foer anvaendning vid framstaellning av dessa.
US5489614A (en) * 1987-11-27 1996-02-06 Orion-Yhtyma Oy Catechol derivatives, their physiologically acceptable salts, esters and use
MTP1031B (en) * 1987-12-24 1990-10-04 Orion Yhtymae Oy New use of cathecol-o-methyl transferase (comt) inhibitors and their physiologically acceptable salts and esters
US5470737A (en) * 1993-06-09 1995-11-28 Mayo Foundation For Medical Education And Research Stably-transformed cells expressing human thiopurine methyltransferase
GB9510481D0 (en) 1995-05-24 1995-07-19 Orion Yhtymae Oy New catechol derivatives
GB9626472D0 (en) 1996-12-20 1997-02-05 Aperia Anita C New use of comt inhibitors
US6169103B1 (en) 1998-03-03 2001-01-02 Warner-Lambert Fluorine-substituted biphenyl butyric acids and their derivatives as inhibitors of matrix metalloproteinases
US6599530B2 (en) * 1998-09-14 2003-07-29 Orion Corporation Oral compacted composition comprising catechol derivatives

Also Published As

Publication number Publication date
US6723754B2 (en) 2004-04-20
EP1263425A1 (fr) 2002-12-11
ATE256461T1 (de) 2004-01-15
CA2403352C (fr) 2009-05-05
JP2003526663A (ja) 2003-09-09
CA2403352A1 (fr) 2001-09-20
JP4874489B2 (ja) 2012-02-15
US20030069316A1 (en) 2003-04-10
EP1263425B1 (fr) 2003-12-17
AU2001246600A1 (en) 2001-09-24
DE60101559D1 (de) 2004-01-29
WO2001068083A1 (fr) 2001-09-20
DE60101559T2 (de) 2004-09-16

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