ATE256461T1 - Benutzung von comt-inhibitoren als analgetika - Google Patents

Benutzung von comt-inhibitoren als analgetika

Info

Publication number
ATE256461T1
ATE256461T1 AT01919513T AT01919513T ATE256461T1 AT E256461 T1 ATE256461 T1 AT E256461T1 AT 01919513 T AT01919513 T AT 01919513T AT 01919513 T AT01919513 T AT 01919513T AT E256461 T1 ATE256461 T1 AT E256461T1
Authority
AT
Austria
Prior art keywords
analgesics
comt inhibitors
comt
inhibitors
pain
Prior art date
Application number
AT01919513T
Other languages
English (en)
Inventor
Paeivi Aho
Inge-Britt Linden
Original Assignee
Orion Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Corp filed Critical Orion Corp
Application granted granted Critical
Publication of ATE256461T1 publication Critical patent/ATE256461T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT01919513T 2000-03-17 2001-03-16 Benutzung von comt-inhibitoren als analgetika ATE256461T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20000635A FI20000635A0 (fi) 2000-03-17 2000-03-17 COMT-inhibiittoreiden käyttö analgeettina
PCT/FI2001/000265 WO2001068083A1 (en) 2000-03-17 2001-03-16 Use of comt inhibitors as analgesics

Publications (1)

Publication Number Publication Date
ATE256461T1 true ATE256461T1 (de) 2004-01-15

Family

ID=8557970

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01919513T ATE256461T1 (de) 2000-03-17 2001-03-16 Benutzung von comt-inhibitoren als analgetika

Country Status (9)

Country Link
US (1) US6723754B2 (de)
EP (1) EP1263425B1 (de)
JP (1) JP4874489B2 (de)
AT (1) ATE256461T1 (de)
AU (1) AU2001246600A1 (de)
CA (1) CA2403352C (de)
DE (1) DE60101559T2 (de)
FI (1) FI20000635A0 (de)
WO (1) WO2001068083A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1782321A4 (de) * 2004-07-23 2009-11-04 Univ North Carolina Verfahren und materialien zur bestimmung von schmerzempfindlichkeit und vorhersage und behandlung zugehöriger störungen
MY148644A (en) * 2005-07-18 2013-05-15 Orion Corp New pharmaceutical compounds
BRPI0613859B8 (pt) 2005-07-26 2021-05-25 Bial Portela & Ca Sa inibidores da comt, seus usos, e composição farmacêutica
EP1845097A1 (de) 2006-04-10 2007-10-17 Portela & Ca., S.A. Oxadiazolderivate als COMT Inihibitoren
CA2572004A1 (en) * 2006-12-08 2008-06-08 Bernard Charles Sherman Tablets comprising entacapone and crospovidone
EP2124947B1 (de) 2007-01-31 2017-07-19 BIAL - Portela & Ca., S.A. Dosierschema für comt-hemmer
CA2718772C (en) 2008-03-17 2017-05-02 David Alexander Learmonth Crystal forms of 5-[3-(2,5-dichloro-4,6-dimethyl-1-oxy-pyridine-3-yl)[1,2,4]oxadiazol-5-yl]-3-nit robenzene-1,2-diol
CN105878242A (zh) 2009-04-01 2016-08-24 巴尔-波特拉及康邦亚股份有限公司 包括硝基儿茶酚衍生物的药物制剂及其制备方法
US20140045900A1 (en) 2011-02-11 2014-02-13 Bial-Portela & Ca, S.A. Administration regime for nitrocatechols
PT3604299T (pt) 2011-12-13 2023-10-31 Bial Portela & Ca Sa Composto químico útil como intermediário para a preparação de um inibidor de catecol-o-metiltransferase
TWI638802B (zh) 2012-05-24 2018-10-21 芬蘭商奧利安公司 兒茶酚ｏ－甲基轉移酶活性抑制化合物
WO2016083863A1 (en) 2014-11-28 2016-06-02 Bial - Portela & Ca, S.A. Medicaments for slowing parkinson's disease
US20210347728A1 (en) 2018-07-25 2021-11-11 Orion Corporation 4,5-dihydroxy-2-(4-methylbenzyl)isophthalonitrile solvates and crystalline forms thereof
WO2020094928A1 (en) 2018-11-09 2020-05-14 Orion Corporation Process for the preparation of 4,5-dihydroxy-2-(4-methylbenzyl)isophthalonitrile
WO2022158991A1 (en) 2021-01-20 2022-07-28 Bial-Portela & Ca., S.A. Treatment of pain associated with parkinson's disease with opicapone in combination with levodopa

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB898879A (en) 1959-10-16 1962-06-14 Smith & Nephew Hydrazine derivatives
DK175069B1 (da) * 1986-03-11 2004-05-24 Hoffmann La Roche Pyrocatecholderivater
US5236952A (en) * 1986-03-11 1993-08-17 Hoffmann-La Roche Inc. Catechol derivatives
FI864875A0 (fi) * 1986-11-28 1986-11-28 Orion Yhtymae Oy Nya farmakologiskt aktiva foereningar, dessa innehaollande kompositioner samt foerfarande och mellanprodukter foer anvaendning vid framstaellning av dessa.
US5283352A (en) * 1986-11-28 1994-02-01 Orion-Yhtyma Oy Pharmacologically active compounds, methods for the preparation thereof and compositions containing the same
YU213587A (en) * 1986-11-28 1989-06-30 Orion Yhtymae Oy Process for obtaining new pharmacologic active cateholic derivatives
US5489614A (en) * 1987-11-27 1996-02-06 Orion-Yhtyma Oy Catechol derivatives, their physiologically acceptable salts, esters and use
MTP1031B (en) * 1987-12-24 1990-10-04 Orion Yhtymae Oy New use of cathecol-o-methyl transferase (comt) inhibitors and their physiologically acceptable salts and esters
US5470737A (en) * 1993-06-09 1995-11-28 Mayo Foundation For Medical Education And Research Stably-transformed cells expressing human thiopurine methyltransferase
GB9510481D0 (en) 1995-05-24 1995-07-19 Orion Yhtymae Oy New catechol derivatives
GB9626472D0 (en) 1996-12-20 1997-02-05 Aperia Anita C New use of comt inhibitors
US6169103B1 (en) * 1998-03-03 2001-01-02 Warner-Lambert Fluorine-substituted biphenyl butyric acids and their derivatives as inhibitors of matrix metalloproteinases
US6599530B2 (en) * 1998-09-14 2003-07-29 Orion Corporation Oral compacted composition comprising catechol derivatives

Also Published As

Publication number Publication date
JP4874489B2 (ja) 2012-02-15
EP1263425B1 (de) 2003-12-17
DE60101559D1 (de) 2004-01-29
EP1263425A1 (de) 2002-12-11
WO2001068083A1 (en) 2001-09-20
CA2403352C (en) 2009-05-05
FI20000635A0 (fi) 2000-03-17
US6723754B2 (en) 2004-04-20
JP2003526663A (ja) 2003-09-09
AU2001246600A1 (en) 2001-09-24
US20030069316A1 (en) 2003-04-10
DE60101559T2 (de) 2004-09-16
CA2403352A1 (en) 2001-09-20

Similar Documents

Publication Publication Date Title
ATE256461T1 (de) Benutzung von comt-inhibitoren als analgetika
DE60141230D1 (de) Verwendung von Botulinum Toxin zur Behandlung von neuralgischen Schmerzen
DE60135087D1 (de) Dipeptidnitrile als inhibitoren von cathepsin k
EE05507B1 (et) Rosuvastatiini ZD4522) kasutamine heterosgootseperekondliku hperkolesteroleemia raviks
HK1069316A1 (en) Hmgb1 protein inhibitors and/or antagonists for the treatment of vascular diseases
ATE323661T1 (de) Behandlung von mineralischen stoffen
TR200200204T2 (tr) MEK inhibitörleri kullanılarak kronik ağrının tedavi edilmesi.
ATE267830T1 (de) Als cox-hemmer verwendbare sulfonylphenylpyrazol- verbindungen
DE60129330D1 (de) Verwendung von cox-2 inhibitoren als immunostimulantien zur behandlung von hiv oder aids
EE9900118A (et) H+,K+-ATPaasi inhibiitorite kasutamine ninapolüüpide ravimisel
PT1242410E (pt) Compostos novos
DE50105735D1 (de) Chlorzoxazon zur behandlung von psoriasis
DE60112148T2 (de) Verwendung von (Per)fluoroetherverbindungen als Zusatzstoffe in Formulierungen zur Holzbehandlung
DE60128009D1 (de) Verwendung von sarp-1 zur behandlung und/oder vorbeugung von scleroderma
GB9626472D0 (en) New use of comt inhibitors
DE69930844D1 (de) Inhibitoren von mycobakterien
ATE228840T1 (de) Neue verwendung von ropivacain zur schmerzbehandlung
ATE302009T1 (de) Ubichinon qn zur behandlung von migräneschmerzen
ATE377586T1 (de) Tripeptidylpeptidaseinhibitoren
ATE236633T1 (de) Topische verwendung von loperamid zur behandlung mikrobieller infektionen
MXPA05010800A (es) Acidos hidroxamicos utiles en el tratamiento de trastornos hiperproliferativos.
MXPA04000418A (es) Tratamiento de dolor cronico con 3-heterocicloxi- y -cicloalquiloxi-3-fenilpropanaminas.
NO20062138L (no) Anvendelse av ifenprodil i behandling av smerte
DE60128374D1 (de) Varianten des hauptallergen par j 2 von parietaria judaica
NO20052379D0 (no) Nye antitumorale forbindelser

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties