FI110063B - Uusi bioaktiivinen tuote ja sen käyttö - Google Patents
Uusi bioaktiivinen tuote ja sen käyttö Download PDFInfo
- Publication number
- FI110063B FI110063B FI982684A FI982684A FI110063B FI 110063 B FI110063 B FI 110063B FI 982684 A FI982684 A FI 982684A FI 982684 A FI982684 A FI 982684A FI 110063 B FI110063 B FI 110063B
- Authority
- FI
- Finland
- Prior art keywords
- bioactive
- fiber
- textile product
- fibers
- product according
- Prior art date
Links
- 230000000975 bioactive effect Effects 0.000 title claims description 29
- 239000000835 fiber Substances 0.000 claims abstract description 49
- 239000005313 bioactive glass Substances 0.000 claims abstract description 33
- 239000004753 textile Substances 0.000 claims abstract description 31
- 210000001519 tissue Anatomy 0.000 claims description 17
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 10
- 230000008468 bone growth Effects 0.000 claims description 8
- 239000000126 substance Substances 0.000 claims description 7
- 239000012530 fluid Substances 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- 239000000741 silica gel Substances 0.000 claims description 4
- 229910002027 silica gel Inorganic materials 0.000 claims description 4
- 239000003795 chemical substances by application Substances 0.000 claims description 3
- 229910052681 coesite Inorganic materials 0.000 claims description 3
- 229910052906 cristobalite Inorganic materials 0.000 claims description 3
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims description 3
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims description 3
- 239000000377 silicon dioxide Substances 0.000 claims description 3
- 235000012239 silicon dioxide Nutrition 0.000 claims description 3
- 229910052682 stishovite Inorganic materials 0.000 claims description 3
- 229910052905 tridymite Inorganic materials 0.000 claims description 3
- 239000004744 fabric Substances 0.000 claims description 2
- 230000001737 promoting effect Effects 0.000 claims description 2
- 239000008186 active pharmaceutical agent Substances 0.000 claims 1
- 229940088679 drug related substance Drugs 0.000 claims 1
- 239000007943 implant Substances 0.000 description 19
- 239000000463 material Substances 0.000 description 10
- 210000000988 bone and bone Anatomy 0.000 description 7
- 239000002131 composite material Substances 0.000 description 7
- 239000002245 particle Substances 0.000 description 7
- 239000011521 glass Substances 0.000 description 6
- 239000004005 microsphere Substances 0.000 description 6
- 239000010936 titanium Substances 0.000 description 5
- 229910052719 titanium Inorganic materials 0.000 description 5
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 4
- 230000011164 ossification Effects 0.000 description 4
- 239000012620 biological material Substances 0.000 description 3
- 239000011159 matrix material Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- 229910019142 PO4 Inorganic materials 0.000 description 2
- 229910004298 SiO 2 Inorganic materials 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000000945 filler Substances 0.000 description 2
- 239000002241 glass-ceramic Substances 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 150000002739 metals Chemical class 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 2
- 239000010452 phosphate Substances 0.000 description 2
- 230000004962 physiological condition Effects 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 238000005245 sintering Methods 0.000 description 2
- 230000003746 surface roughness Effects 0.000 description 2
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 101100348017 Drosophila melanogaster Nazo gene Proteins 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- 229910052586 apatite Inorganic materials 0.000 description 1
- 239000012237 artificial material Substances 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 238000005422 blasting Methods 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 229910000389 calcium phosphate Inorganic materials 0.000 description 1
- 235000011010 calcium phosphates Nutrition 0.000 description 1
- QXJJQWWVWRCVQT-UHFFFAOYSA-K calcium;sodium;phosphate Chemical compound [Na+].[Ca+2].[O-]P([O-])([O-])=O QXJJQWWVWRCVQT-UHFFFAOYSA-K 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000004663 cell proliferation Effects 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 238000013270 controlled release Methods 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 239000003365 glass fiber Substances 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 239000003049 inorganic solvent Substances 0.000 description 1
- 229910001867 inorganic solvent Inorganic materials 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 230000000399 orthopedic effect Effects 0.000 description 1
- VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000004043 responsiveness Effects 0.000 description 1
- 238000007788 roughening Methods 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 229920001169 thermoplastic Polymers 0.000 description 1
- 210000004746 tooth root Anatomy 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 210000000689 upper leg Anatomy 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C4/00—Compositions for glass with special properties
- C03C4/0007—Compositions for glass with special properties for biologically-compatible glass
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/10—Ceramics or glasses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/306—Other specific inorganic materials not covered by A61L27/303 - A61L27/32
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/32—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C13/00—Fibre or filament compositions
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C3/00—Glass compositions
- C03C3/04—Glass compositions containing silica
- C03C3/076—Glass compositions containing silica with 40% to 90% silica, by weight
- C03C3/097—Glass compositions containing silica with 40% to 90% silica, by weight containing phosphorus, niobium or tantalum
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C4/00—Compositions for glass with special properties
- C03C4/0007—Compositions for glass with special properties for biologically-compatible glass
- C03C4/0014—Biodegradable glass
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2/30965—Reinforcing the prosthesis by embedding particles or fibres during moulding or dipping
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30667—Features concerning an interaction with the environment or a particular use of the prosthesis
- A61F2002/30677—Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00329—Glasses, e.g. bioglass
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Veterinary Medicine (AREA)
- Materials Engineering (AREA)
- Geochemistry & Mineralogy (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Ceramic Engineering (AREA)
- Composite Materials (AREA)
- Biodiversity & Conservation Biology (AREA)
- Biomedical Technology (AREA)
- Materials For Medical Uses (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
- Dental Preparations (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI982684A FI110063B (fi) | 1998-12-11 | 1998-12-11 | Uusi bioaktiivinen tuote ja sen käyttö |
| DE69929625T DE69929625T2 (de) | 1998-12-11 | 1999-11-19 | Poröses Textilprodukt aus bioaktive Glasfasern und seine Verwendung |
| AT99958198T ATE316389T1 (de) | 1998-12-11 | 1999-11-19 | Poröses textilprodukt aus bioaktive glasfasern und seine verwendung |
| EP99958198A EP1137448B1 (en) | 1998-12-11 | 1999-11-19 | Porous textile product made from bioactive glass fibers and its use |
| CA002354850A CA2354850C (en) | 1998-12-11 | 1999-11-19 | Textile product made from bioactive glass fibers and its use |
| ES99958198T ES2255318T3 (es) | 1998-12-11 | 1999-11-19 | Producto textil poroso realizado a partir de fibras de vidrio bioactivo y su utilizacion. |
| DK99958198T DK1137448T3 (da) | 1998-12-11 | 1999-11-19 | Poröst tekstilprodukt fremstillet af bioaktive glasfibre og anvendelse deraf |
| JP2000587827A JP2002532158A (ja) | 1998-12-11 | 1999-11-19 | 新しい生体活性生成品及びその使用 |
| PCT/FI1999/000961 WO2000035509A1 (en) | 1998-12-11 | 1999-11-19 | A novel bioactive product and its use |
| AU15617/00A AU761459B2 (en) | 1998-12-11 | 1999-11-19 | A novel bioactive product and its use |
| US09/875,017 US6517857B2 (en) | 1998-12-11 | 2001-06-07 | Bioactive product and its use |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI982684A FI110063B (fi) | 1998-12-11 | 1998-12-11 | Uusi bioaktiivinen tuote ja sen käyttö |
| FI982684 | 1998-12-11 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI982684A0 FI982684A0 (fi) | 1998-12-11 |
| FI982684L FI982684L (fi) | 2000-06-12 |
| FI110063B true FI110063B (fi) | 2002-11-29 |
Family
ID=8553092
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI982684A FI110063B (fi) | 1998-12-11 | 1998-12-11 | Uusi bioaktiivinen tuote ja sen käyttö |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6517857B2 (https=) |
| EP (1) | EP1137448B1 (https=) |
| JP (1) | JP2002532158A (https=) |
| AT (1) | ATE316389T1 (https=) |
| AU (1) | AU761459B2 (https=) |
| CA (1) | CA2354850C (https=) |
| DE (1) | DE69929625T2 (https=) |
| DK (1) | DK1137448T3 (https=) |
| ES (1) | ES2255318T3 (https=) |
| FI (1) | FI110063B (https=) |
| WO (1) | WO2000035509A1 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI107709B (fi) * | 2000-03-07 | 2001-09-28 | Vivoxid Oy | Menetelmä bioaktiivisen lasin pinnan karhentamiseksi |
| US7005135B2 (en) * | 2001-01-30 | 2006-02-28 | Ethicon Inc. | Glass scaffolds with controlled resorption rates and methods for making same |
| FI117963B (fi) | 2001-04-26 | 2007-05-15 | Eija Marjut Pirhonen | Luuta korvaavat materiaalit |
| EP3111895B1 (en) | 2004-02-03 | 2019-09-04 | The General Hospital Corporation | Highly crystalline cross-linked oxidation-resistant polyethylene |
| EP1611906A1 (en) * | 2004-06-30 | 2006-01-04 | YLI-URPO, Antti | A multilayer material |
| EP2441781A1 (en) | 2005-08-22 | 2012-04-18 | The General Hospital Corporation d/b/a Massachusetts General Hospital | Highly crystalline polyethylene |
| US20070258916A1 (en) * | 2006-04-14 | 2007-11-08 | Oregon Health & Science University | Oral compositions for treating tooth hypersensitivity |
| WO2008000888A2 (en) * | 2006-06-28 | 2008-01-03 | Vivoxid Oy | Implant containing a source of oxygen |
| EP1872806A1 (en) * | 2006-06-28 | 2008-01-02 | Vivoxid Oy | Implant, its uses and methods for making it |
| KR100791518B1 (ko) * | 2006-12-21 | 2008-01-04 | 단국대학교 산학협력단 | 생체활성 유리 나노섬유(ｂｇｎｆ) 및 그 제조방법 |
| KR100791512B1 (ko) | 2006-12-21 | 2008-01-04 | 단국대학교 산학협력단 | 나노구조로 이루어진 하이브리드형 조직재생용 멤브레인과스캐폴드 및 그들의 제조방법 |
| DE102007018200A1 (de) * | 2007-04-16 | 2008-10-23 | Gehl, Gerolf, Dr. | Verfahren zum Herstellen und insbesondere zum Wiederherstellen einer Gewebestruktur |
| US20090192609A1 (en) * | 2008-01-29 | 2009-07-30 | Zimmer, Inc. | Implant device for use in an implant system |
| US20100136086A1 (en) * | 2008-05-12 | 2010-06-03 | Day Thomas E | Dynamic bioactive nanofiber scaffolding |
| US9402724B2 (en) * | 2008-05-12 | 2016-08-02 | Mo-Sci Corporation | Dynamic bioactive nanofiber scaffolding |
| KR101047897B1 (ko) * | 2008-10-22 | 2011-07-08 | 단국대학교 산학협력단 | 단백질 결합형 생체활성유리 나노섬유 및 이의 제조방법 |
| US20110206828A1 (en) * | 2009-07-10 | 2011-08-25 | Bio2 Technologies, Inc. | Devices and Methods for Tissue Engineering |
| IN2012DN01107A (https=) | 2009-07-10 | 2015-04-10 | Bio2 Technologies Inc | |
| US9775721B2 (en) | 2009-07-10 | 2017-10-03 | Bio2 Technologies, Inc. | Resorbable interbody device |
| KR20120101021A (ko) * | 2009-10-29 | 2012-09-12 | 프로시다이안 인코포레이티드 | 골 이식재 |
| CA2779109A1 (en) | 2009-10-29 | 2011-05-05 | Prosidyan, Inc. | Dynamic bioactive bone graft material having an engineered porosity |
| US8551525B2 (en) | 2010-12-23 | 2013-10-08 | Biostructures, Llc | Bone graft materials and methods |
| BR102013020961A2 (pt) | 2013-08-12 | 2016-03-08 | Univ Fed De São Carlos | composição vítrea, fibras e tecidos vítreos bioativos e artigos |
| US10238507B2 (en) | 2015-01-12 | 2019-03-26 | Surgentec, Llc | Bone graft delivery system and method for using same |
| US11013836B2 (en) * | 2016-06-16 | 2021-05-25 | The Curators Of The University Of Missouri | Inorganic biodegradable substrates for devices and systems |
| US11116647B2 (en) | 2018-04-13 | 2021-09-14 | Surgentec, Llc | Bone graft delivery system and method for using same |
| US10687828B2 (en) | 2018-04-13 | 2020-06-23 | Surgentec, Llc | Bone graft delivery system and method for using same |
| TWI890935B (zh) * | 2022-03-17 | 2025-07-21 | 巨晰光纖股份有限公司 | 用於再生醫材之生物玻璃纖維及其應用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1477899A (en) * | 1973-09-17 | 1977-06-29 | Leitz Ernst Gmbh | Manufacture of therapeutically useful composite materials |
| US4604097A (en) * | 1985-02-19 | 1986-08-05 | University Of Dayton | Bioabsorbable glass fibers for use in the reinforcement of bioabsorbable polymers for bone fixation devices and artificial ligaments |
| AU630484B2 (en) * | 1989-08-11 | 1992-10-29 | Isover Saint-Gobain | Glass fibres capable of decomposing in a physiological medium |
| IT1240938B (it) * | 1990-02-08 | 1993-12-27 | S.E.I.P.I. Societa' Esportazione Importazione Prodotti Industriali | Composizione vetrosa bioattiva per impianti ossei e prodotti ottenuti con tale composizione o che la comprendono |
| JPH06116114A (ja) * | 1992-10-09 | 1994-04-26 | Nikon Corp | 骨充填材 |
| US5468544A (en) * | 1993-11-15 | 1995-11-21 | The Trustees Of The University Of Pennsylvania | Composite materials using bone bioactive glass and ceramic fibers |
| FI101129B (sv) * | 1995-01-13 | 1998-04-30 | Vivoxid Oy | Nya bioaktiva glas och deras användning |
| FI103715B (fi) | 1997-04-21 | 1999-08-31 | Vivoxid Oy | Uusi komposiitti ja sen käyttö |
-
1998
- 1998-12-11 FI FI982684A patent/FI110063B/fi not_active IP Right Cessation
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1999
- 1999-11-19 EP EP99958198A patent/EP1137448B1/en not_active Expired - Lifetime
- 1999-11-19 CA CA002354850A patent/CA2354850C/en not_active Expired - Fee Related
- 1999-11-19 AU AU15617/00A patent/AU761459B2/en not_active Ceased
- 1999-11-19 WO PCT/FI1999/000961 patent/WO2000035509A1/en not_active Ceased
- 1999-11-19 DK DK99958198T patent/DK1137448T3/da active
- 1999-11-19 AT AT99958198T patent/ATE316389T1/de not_active IP Right Cessation
- 1999-11-19 ES ES99958198T patent/ES2255318T3/es not_active Expired - Lifetime
- 1999-11-19 DE DE69929625T patent/DE69929625T2/de not_active Expired - Fee Related
- 1999-11-19 JP JP2000587827A patent/JP2002532158A/ja active Pending
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Also Published As
| Publication number | Publication date |
|---|---|
| FI982684A0 (fi) | 1998-12-11 |
| ATE316389T1 (de) | 2006-02-15 |
| CA2354850A1 (en) | 2000-06-22 |
| DK1137448T3 (da) | 2006-05-08 |
| FI982684L (fi) | 2000-06-12 |
| DE69929625D1 (de) | 2006-04-13 |
| AU761459B2 (en) | 2003-06-05 |
| JP2002532158A (ja) | 2002-10-02 |
| WO2000035509A1 (en) | 2000-06-22 |
| EP1137448B1 (en) | 2006-01-25 |
| US20010041325A1 (en) | 2001-11-15 |
| AU1561700A (en) | 2000-07-03 |
| US6517857B2 (en) | 2003-02-11 |
| CA2354850C (en) | 2009-03-24 |
| EP1137448A1 (en) | 2001-10-04 |
| DE69929625T2 (de) | 2006-08-10 |
| ES2255318T3 (es) | 2006-06-16 |
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