FI104324B1 - Förfarande för framställning av terapeutiskt användbart, olösligt svälbart polymeriskt allylammoniumderivat - Google Patents

Förfarande för framställning av terapeutiskt användbart, olösligt svälbart polymeriskt allylammoniumderivat

Info

Publication number
FI104324B1
FI104324B1 FI923476A FI923476A FI104324B1 FI 104324 B1 FI104324 B1 FI 104324B1 FI 923476 A FI923476 A FI 923476A FI 923476 A FI923476 A FI 923476A FI 104324 B1 FI104324 B1 FI 104324B1
Authority
FI
Finland
Prior art keywords
insoluble
preparation
therapeutically useful
ammonium derivative
swellable polymeric
Prior art date
Application number
FI923476A
Other languages
English (en)
Finnish (fi)
Other versions
FI104324B (sv
FI923476A (fi
FI923476A0 (fi
Inventor
Fergus Mctaggart
Graham John Smith
Denis Pemberton
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909026616A external-priority patent/GB9026616D0/en
Priority claimed from GB919110180A external-priority patent/GB9110180D0/en
Application filed by Ici Plc filed Critical Ici Plc
Publication of FI923476A publication Critical patent/FI923476A/fi
Publication of FI923476A0 publication Critical patent/FI923476A0/fi
Application granted granted Critical
Publication of FI104324B1 publication Critical patent/FI104324B1/sv
Publication of FI104324B publication Critical patent/FI104324B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F226/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • C08F226/02—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a single or double bond to nitrogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/02—Alkylation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Insulating Materials (AREA)
  • Inorganic Insulating Materials (AREA)
FI923476A 1990-12-07 1992-07-31 Förfarande för framställning av terapeutiskt användbart, olösligt svälbart polymeriskt allylammoniumderivat FI104324B (sv)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB909026616A GB9026616D0 (en) 1990-12-07 1990-12-07 Nitrogen derivatives
GB919110180A GB9110180D0 (en) 1991-05-10 1991-05-10 Nitrogen derivatives
PCT/GB1991/002168 WO1992010522A1 (en) 1990-12-07 1991-12-06 Quaternary crosslinked allylammoniumpolymers, preparation and use thereof

Publications (4)

Publication Number Publication Date
FI923476A FI923476A (fi) 1992-07-31
FI923476A0 FI923476A0 (fi) 1992-07-31
FI104324B1 true FI104324B1 (sv) 1999-12-31
FI104324B FI104324B (sv) 1999-12-31

Family

ID=26298074

Family Applications (1)

Application Number Title Priority Date Filing Date
FI923476A FI104324B (sv) 1990-12-07 1992-07-31 Förfarande för framställning av terapeutiskt användbart, olösligt svälbart polymeriskt allylammoniumderivat

Country Status (15)

Country Link
US (2) US5462730A (sv)
EP (1) EP0513300B1 (sv)
KR (1) KR927003663A (sv)
AT (1) ATE153037T1 (sv)
AU (1) AU640845B2 (sv)
CA (1) CA2056862A1 (sv)
DE (1) DE69126126T2 (sv)
FI (1) FI104324B (sv)
HU (1) HUT64370A (sv)
IE (1) IE914179A1 (sv)
IL (1) IL100253A (sv)
NZ (1) NZ240844A (sv)
PL (1) PL295641A1 (sv)
PT (1) PT99715B (sv)
WO (1) WO1992010522A1 (sv)

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US5487888A (en) 1993-05-20 1996-01-30 Geltex, Inc. Iron-binding polymers for oral administration
US5618530A (en) * 1994-06-10 1997-04-08 Geltex Pharmaceuticals, Inc. Hydrophobic amine polymer sequestrant and method of cholesterol depletion
US6129910A (en) * 1993-06-02 2000-10-10 Geltex Pharmaceuticals, Inc. Water-insoluble noncrosslinked bile acid sequestrants
US5703188A (en) * 1993-06-02 1997-12-30 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5929184A (en) * 1993-06-02 1999-07-27 Geltex Pharmaceuticals, Inc. Hydrophilic nonamine-containing and amine-containing copolymers and their use as bile acid sequestrants
US5607669A (en) * 1994-06-10 1997-03-04 Geltex Pharmaceuticals, Inc. Amine polymer sequestrant and method of cholesterol depletion
US5900475A (en) * 1994-06-10 1999-05-04 Geltex Pharmaceuticals, Inc. Hydrophobic sequestrant for cholesterol depletion
US5624963A (en) * 1993-06-02 1997-04-29 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5667775A (en) 1993-08-11 1997-09-16 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US5496545A (en) * 1993-08-11 1996-03-05 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
TW474813B (en) 1994-06-10 2002-02-01 Geltex Pharma Inc Alkylated composition for removing bile salts from a patient
US6203785B1 (en) 1996-12-30 2001-03-20 Geltex Pharmaceuticals, Inc. Poly(diallylamine)-based bile acid sequestrants
US5925379A (en) * 1997-03-27 1999-07-20 Geltex Pharmaceuticals, Inc. Interpenetrating polymer networks for sequestration of bile acids
US6423754B1 (en) * 1997-06-18 2002-07-23 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with polyallylamine polymers
US6726905B1 (en) 1997-11-05 2004-04-27 Genzyme Corporation Poly (diallylamines)-based phosphate binders
US6083497A (en) * 1997-11-05 2000-07-04 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
EP1881013A1 (en) * 1999-04-16 2008-01-23 Abbott Laboratories Process for producing cross-linked polyallylamine hydrochloride
US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
US6908609B2 (en) * 2000-11-20 2005-06-21 Dow Global Technologies Inc. In vivo use of water absorbent polymers
EP1847271A3 (en) * 2000-11-20 2008-08-06 Sorbent Therapeutics, Inc. Water-absorbent polymers and their use as a medicament
AT409630B (de) 2000-12-13 2002-09-25 Dsm Fine Chem Austria Gmbh Alkylierung von n-bzw. amino- oder ammoniumgruppen haltigen, vernetzten polymeren
AU2002252632B2 (en) * 2001-04-18 2004-09-23 Genzyme Corporation Low salt forms of polyallylamine
JP2004526778A (ja) * 2001-04-18 2004-09-02 ジェンザイム コーポレーション 脂肪族ポリアミンを用いるｘ症候群の処置方法
WO2004089997A1 (ja) * 2003-04-01 2004-10-21 Nitto Boseki Co., Ltd. 変性ポリアリルアミンおよびその製造方法
US7854924B2 (en) 2004-03-30 2010-12-21 Relypsa, Inc. Methods and compositions for treatment of ion imbalances
US8282960B2 (en) 2004-03-30 2012-10-09 Relypsa, Inc. Ion binding compositions
EP1732523B9 (en) 2004-03-30 2010-06-02 Relypsa, Inc. Potassium binding polymers and uses thereof
US7429394B2 (en) 2004-03-30 2008-09-30 Relypsa, Inc. Ion binding compositions
US7556799B2 (en) 2004-03-30 2009-07-07 Relypsa, Inc. Ion binding polymers and uses thereof
US8192758B2 (en) 2004-03-30 2012-06-05 Relypsa, Inc. Ion binding compositions
US7985418B2 (en) * 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
JP2008526771A (ja) * 2004-12-30 2008-07-24 ジェンザイム コーポレーション 高リン酸血症のための亜鉛含有処置
JP2009507019A (ja) 2005-09-02 2009-02-19 ジェンザイム・コーポレーション リン酸塩を除去する方法およびそれに使用される重合体
DK1924246T3 (en) 2005-09-15 2016-01-18 Genzyme Corp PORTION LETTER DEFINITION OF amine polymers
GB2446076B (en) 2005-09-30 2010-11-24 Ilypsa Inc Methods for preparing core-shell composites having cross-linked shells and core-shell composites resulting therefrom
CA2624170C (en) 2005-09-30 2014-02-25 Ilypsa, Inc. Methods and compositions for selectively removing potassium ion from the gastrointestinal tract of a mammal
EP2043627A2 (en) * 2006-07-05 2009-04-08 Genzyme Corporation Iron(ii)-containing treatments for hyperphosphatemia
EP2066293A2 (en) 2006-09-29 2009-06-10 Genzyme Corporation Amide dendrimer compositions
BRPI0720234A2 (pt) 2006-12-14 2013-12-24 Genzyme Corp Composição farmacêutica
US8337824B2 (en) 2008-08-22 2012-12-25 Relypsa, Inc. Linear polyol stabilized polyfluoroacrylate compositions
KR20210005314A (ko) 2012-10-08 2021-01-13 리립사, 인크. 고혈압 및 고칼륨혈증을 치료하기 위한 칼륨-결합제
MA41202A (fr) 2014-12-18 2017-10-24 Genzyme Corp Copolymères polydiallymine réticulé pour le traitement du diabète de type 2

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU509755B2 (en) * 1976-12-13 1980-05-22 Commonwealth Scientific And Industrial Research Organisation Basic ion exchange resins
US4759923A (en) * 1987-06-25 1988-07-26 Hercules Incorporated Process for lowering serum cholesterol using poly(diallylmethylamine) derivatives
EP0334673B1 (en) * 1988-03-24 1993-10-20 Taisho Pharmaceutical Co. Ltd Cholesterol-lowering agents
GB8829835D0 (en) * 1988-12-21 1989-02-15 Smith Kline French Lab Compounds
GB8911719D0 (en) * 1989-05-22 1989-07-05 Smith Kline French Lab Compounds
GB8928278D0 (en) * 1989-12-14 1990-02-21 Smith Kline French Lab Compounds

Also Published As

Publication number Publication date
DE69126126T2 (de) 1997-08-28
IL100253A0 (en) 1992-09-06
HUT64370A (en) 1993-12-28
PT99715A (pt) 1992-10-30
US5462730A (en) 1995-10-31
IL100253A (en) 1995-11-27
ATE153037T1 (de) 1997-05-15
DE69126126D1 (de) 1997-06-19
AU640845B2 (en) 1993-09-02
WO1992010522A1 (en) 1992-06-25
FI104324B (sv) 1999-12-31
PT99715B (pt) 1999-05-31
NZ240844A (en) 1993-12-23
AU9046691A (en) 1992-07-08
CA2056862A1 (en) 1992-06-08
KR927003663A (ko) 1992-12-18
FI923476A (fi) 1992-07-31
HU9202460D0 (en) 1992-10-28
US5589166A (en) 1996-12-31
IE914179A1 (en) 1992-06-17
EP0513300A1 (en) 1992-11-19
EP0513300B1 (en) 1997-05-14
PL295641A1 (en) 1993-08-09
FI923476A0 (fi) 1992-07-31

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