FI101700B1 - Menetelmä terapeuttisesti käyttökelpoisen, optisesti aktiivisen 2-amino-N-(2,6-dimetyylifenyyli)-N-[3-(3-pyridyyli)-propyyli]propanamidin happoadditiosuolan valmistamiseksi - Google Patents

Menetelmä terapeuttisesti käyttökelpoisen, optisesti aktiivisen 2-amino-N-(2,6-dimetyylifenyyli)-N-[3-(3-pyridyyli)-propyyli]propanamidin happoadditiosuolan valmistamiseksi

Info

Publication number
FI101700B1
FI101700B1 FI913774A FI913774A FI101700B1 FI 101700 B1 FI101700 B1 FI 101700B1 FI 913774 A FI913774 A FI 913774A FI 913774 A FI913774 A FI 913774A FI 101700 B1 FI101700 B1 FI 101700B1
Authority
FI
Finland
Prior art keywords
acid addition
optically active
propanamide
dimethylphenyl
pyridyl
Prior art date
Application number
FI913774A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI913774A0 (fi
FI101700B (fi
FI913774A (fi
Inventor
Tetsuhide Kamijo
Toshiaki Yamaguchi
Kazuhiko Ikegami
Original Assignee
Kissei Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kissei Pharmaceutical filed Critical Kissei Pharmaceutical
Publication of FI913774A0 publication Critical patent/FI913774A0/fi
Publication of FI913774A publication Critical patent/FI913774A/fi
Application granted granted Critical
Publication of FI101700B1 publication Critical patent/FI101700B1/fi
Publication of FI101700B publication Critical patent/FI101700B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/255—Tartaric acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
FI913774A 1990-08-08 1991-08-08 Menetelmä terapeuttisesti käyttökelpoisen, optisesti aktiivisen 2-amin o-N-(2,6-dimetyylifenyyli)-N-£3-(3-pyridyyli)-propyyli|propanamidin ha ppoadditiosuolan valmistamiseksi FI101700B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2211208A JP2514855B2 (ja) 1990-08-08 1990-08-08 光学活性なアラニンアニリド誘導体の酸付加塩
JP21120890 1990-08-08

Publications (4)

Publication Number Publication Date
FI913774A0 FI913774A0 (fi) 1991-08-08
FI913774A FI913774A (fi) 1992-02-09
FI101700B1 true FI101700B1 (fi) 1998-08-14
FI101700B FI101700B (fi) 1998-08-14

Family

ID=16602123

Family Applications (1)

Application Number Title Priority Date Filing Date
FI913774A FI101700B (fi) 1990-08-08 1991-08-08 Menetelmä terapeuttisesti käyttökelpoisen, optisesti aktiivisen 2-amin o-N-(2,6-dimetyylifenyyli)-N-£3-(3-pyridyyli)-propyyli|propanamidin ha ppoadditiosuolan valmistamiseksi

Country Status (13)

Country Link
EP (1) EP0472325B1 (no)
JP (1) JP2514855B2 (no)
KR (1) KR100192531B1 (no)
AT (1) ATE116296T1 (no)
AU (1) AU646276B2 (no)
CA (1) CA2048714A1 (no)
DE (1) DE69106276T2 (no)
DK (1) DK143991A (no)
ES (1) ES2066363T3 (no)
FI (1) FI101700B (no)
HK (1) HK1003787A1 (no)
HU (1) HU213210B (no)
NO (1) NO913004D0 (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9320273D0 (en) * 1993-04-01 1993-11-17 Fisons Corp Compound useful in therapy
ZA942140B (en) * 1993-04-01 1994-10-03 Fisons Corp Salt of (S)-alpha-phenyl-2-pyridineethanamine useful in therapy
NZ593282A (en) 2008-12-24 2013-06-28 Astrazeneca Ab Ethanamine compounds and their use for treating depression

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE786875A (fr) * 1971-07-28 1973-01-29 Astra Pharma Prod Amide, methode pour sa preparation et ses compositions therapeutiques
US4696930A (en) * 1985-04-12 1987-09-29 Hoffmann-La Roche Inc. N-(heteroarylalkyl)acylanilide derivatives as antiarrhythmic agents
JPS6452797A (en) * 1987-01-06 1989-02-28 Takeda Chemical Industries Ltd Production of crystalline trh-tartrate

Also Published As

Publication number Publication date
JP2514855B2 (ja) 1996-07-10
AU646276B2 (en) 1994-02-17
DE69106276D1 (de) 1995-02-09
HU213210B (en) 1997-03-28
ES2066363T3 (es) 1995-03-01
HK1003787A1 (en) 1998-11-06
CA2048714A1 (en) 1992-02-09
EP0472325B1 (en) 1994-12-28
JPH0495072A (ja) 1992-03-27
DE69106276T2 (de) 1995-05-18
KR100192531B1 (ko) 1999-06-15
HUT58292A (en) 1992-02-28
EP0472325A2 (en) 1992-02-26
EP0472325A3 (en) 1992-03-04
DK143991D0 (da) 1991-08-07
DK143991A (da) 1992-02-09
ATE116296T1 (de) 1995-01-15
KR920004334A (ko) 1992-03-27
NO913004D0 (no) 1991-08-01
FI913774A0 (fi) 1991-08-08
FI101700B (fi) 1998-08-14
FI913774A (fi) 1992-02-09
AU8145891A (en) 1992-02-13
HU912640D0 (en) 1992-01-28

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