ES8801768A1 - Un sistema osmotico lipidico para dispersar agentes farmacologicamente activos. - Google Patents

Un sistema osmotico lipidico para dispersar agentes farmacologicamente activos.

Info

Publication number
ES8801768A1
ES8801768A1 ES551505A ES551505A ES8801768A1 ES 8801768 A1 ES8801768 A1 ES 8801768A1 ES 551505 A ES551505 A ES 551505A ES 551505 A ES551505 A ES 551505A ES 8801768 A1 ES8801768 A1 ES 8801768A1
Authority
ES
Spain
Prior art keywords
lipid
water
osmotic
active agent
lipid carrier
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES551505A
Other languages
English (en)
Other versions
ES551505A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES8801768A1 publication Critical patent/ES8801768A1/es
Publication of ES551505A0 publication Critical patent/ES551505A0/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Fats And Perfumes (AREA)
  • External Artificial Organs (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SISTEMA OSMOTICO LIPIDICO PARA DISPENSAR AGENTES FARMACOLOGICAMENTE ACTIVOS. CONSTA DE UN NUCLEO QUE COMPRENDE UNA CANTIDAD BENEFICIOSA DE POR LO MENOS UN AGENTE ACTIVO SUSTANCIALMENTE INSOLUBLE EN AGUA QUE ES SOLUBLE EN LIPIDOS O MOJABLE POR LIPIDOS, POR LO MENOS UN PORTADOR LIPIDICO NO MISCIBLE CON AGUA, EN CANTIDAD SUFICIENTE PARA GARANTIZAR LA LIBERACION DEL PORTADOR LIPIDICO DE LA BOMBA;Y DE UNA PARED INSOLUBLE EN AGUA QUE CIRCUNDA EL NUCLEO, LA CUAL ES MOJADA POR EL PORTADOR LIPIDICO CON PREFERENCIA SOBRE UNA SOLUCION ACUOSA DEL AGENTE OSMOTICO.
ES551505A 1985-02-01 1986-01-31 Un sistema osmotico lipidico para dispersar agentes farmacologicamente activos. Expired ES8801768A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/697,105 US4685918A (en) 1985-02-01 1985-02-01 Lipid osmotic pump

Publications (2)

Publication Number Publication Date
ES8801768A1 true ES8801768A1 (es) 1988-02-16
ES551505A0 ES551505A0 (es) 1988-02-16

Family

ID=24799818

Family Applications (1)

Application Number Title Priority Date Filing Date
ES551505A Expired ES8801768A1 (es) 1985-02-01 1986-01-31 Un sistema osmotico lipidico para dispersar agentes farmacologicamente activos.

Country Status (11)

Country Link
US (1) US4685918A (es)
EP (1) EP0190969B1 (es)
JP (1) JPH0655666B2 (es)
AT (1) ATE85889T1 (es)
CA (1) CA1264133A (es)
CY (1) CY1861A (es)
DE (1) DE3687799T2 (es)
DK (1) DK175532B1 (es)
ES (1) ES8801768A1 (es)
HK (1) HK102995A (es)
IE (1) IE59888B1 (es)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2189699A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated acid-labile medicaments
US4983400A (en) * 1986-06-16 1991-01-08 Merck & Co., Inc. Controlled release combination of carbidopa/levodopa
USRE34990E (en) * 1986-08-07 1995-07-04 Ciba-Geigy Corporation Oral therapeutic system having systemic action
CH668187A5 (de) * 1986-08-07 1988-12-15 Ciba Geigy Ag Therapeutisches system mit systemischer wirkung.
US5030632A (en) * 1986-09-23 1991-07-09 Sandoz Pharm. Corp. Low dose temazepam
US5629310A (en) * 1986-09-23 1997-05-13 Sterling; William R. Low dose temazepam
US5211954A (en) * 1986-09-23 1993-05-18 Sandoz Ltd. Low dose temazepam
ATE72111T1 (de) * 1987-01-14 1992-02-15 Ciba Geigy Ag Therapeutisches system fuer schwerloesliche wirkstoffe.
GB8717168D0 (en) * 1987-07-21 1987-08-26 Roussel Lab Ltd Controlled-release device
CA1331563C (en) * 1987-08-03 1994-08-23 Gaylen M. Zentner Device for the controlled release of drugs with donnan-like modulation by charged insoluble resins
AU608891B2 (en) * 1987-09-24 1991-04-18 Merck & Co., Inc. Solubility modulated drug delivery device
US5030203A (en) * 1987-11-16 1991-07-09 Baxter International Inc. Ampule for controlled administration of beneficial agent
US5510115A (en) * 1987-11-16 1996-04-23 Baxter Travenol Laboratories, Inc. Method and composition for administration of beneficial agent by controlled dissolution
IL92966A (en) * 1989-01-12 1995-07-31 Pfizer Hydrogel-operated release devices
US5030452A (en) * 1989-01-12 1991-07-09 Pfizer Inc. Dispensing devices powered by lyotropic liquid crystals
US5108756A (en) * 1989-01-12 1992-04-28 Pfizer Inc. Dispensing devices powered by lyotropic liquid crystals
CA2008775C (en) * 1989-02-24 1998-12-22 Alberto Ferro Nail lacquer
EP0550641B1 (en) * 1990-09-28 1994-05-25 Pfizer Inc. Dispensing device containing a hydrophobic medium
DE4101873C2 (de) * 1991-01-23 1993-12-09 Isis Pharma Gmbh Peroral applizierbare Arzneiform zur Behandlung zentraler Dopaminmangelzustände
CA2082185C (en) * 1991-11-26 2004-01-20 Alexander R. Pokora Protease catalyzed treatments of lignocellulose materials
US5484607A (en) * 1993-10-13 1996-01-16 Horacek; H. Joseph Extended release clonidine formulation
US5798119A (en) * 1995-06-13 1998-08-25 S. C. Johnson & Son, Inc. Osmotic-delivery devices having vapor-permeable coatings
US5786022A (en) * 1996-10-31 1998-07-28 Ethicon, Inc. Coating mixture for surgical articles
AR026148A1 (es) * 2000-01-21 2003-01-29 Osmotica Argentina S A Dispositivo osmotico con pasaje preformado que aumenta de tamano
US6464688B1 (en) 2000-02-15 2002-10-15 Microsolutions, Inc. Osmotic pump delivery system with flexible drug compartment
US20020090388A1 (en) * 2000-12-01 2002-07-11 Humes H. David Intravascular drug delivery device and use therefor
IN190699B (es) 2001-02-02 2003-08-16 Sun Pharmaceutical Ind Ltd
US6632217B2 (en) 2001-04-19 2003-10-14 Microsolutions, Inc. Implantable osmotic pump
WO2003096968A2 (en) * 2002-05-15 2003-11-27 Sun Pharmaceutical Industries Limited Oral osmotic controlled drug delivery system
JP2007526341A (ja) * 2004-03-03 2007-09-13 スフェリックス， インコーポレイテッド 疎水性薬物のためのポリマー薬物送達システム
US20060045891A1 (en) * 2004-08-24 2006-03-02 Lovalenti Phillip M Density-matched suspension vehicles and pharmaceutical suspensions
US20060045865A1 (en) * 2004-08-27 2006-03-02 Spherics, Inc. Controlled regional oral delivery
US20090081296A1 (en) * 2006-02-02 2009-03-26 Humes H David Extracorporeal cell-based therapeutic device and delivery system
CA2637686A1 (en) 2006-02-02 2007-08-16 Innovative Bio Therapies An extracorporeal cell-based therapeutic device and delivery system
EP2155170A2 (en) * 2007-06-08 2010-02-24 Addrenex Pharmaceuticals, Inc. Extended release formulation and method of treating adrenergic dysregulation
US20100172991A1 (en) * 2007-06-08 2010-07-08 Henry Joseph Horacek Extended Release Formulation and Methods of Treating Adrenergic Dysregulation
US20090148532A1 (en) * 2007-12-06 2009-06-11 Venkatesh Gopi M Preparation of controlled release skeletal muscle relaxant dosage forms
US9029144B2 (en) * 2008-06-18 2015-05-12 Innovative Bio Therapies, Inc. Methods for enhanced propagation of cells

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3854480A (en) * 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
US3948254A (en) * 1971-11-08 1976-04-06 Alza Corporation Novel drug delivery device
US3819390A (en) * 1972-01-24 1974-06-25 Anheuser Busch Lipophilic cellulose sponges
US3995632A (en) * 1973-05-04 1976-12-07 Alza Corporation Osmotic dispenser
US4111202A (en) * 1976-11-22 1978-09-05 Alza Corporation Osmotic system for the controlled and delivery of agent over time
US4256108A (en) * 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4200098A (en) * 1978-10-23 1980-04-29 Alza Corporation Osmotic system with distribution zone for dispensing beneficial agent
US4350271A (en) * 1980-08-22 1982-09-21 Alza Corporation Water absorbing fluid dispenser
US4522625A (en) * 1982-09-29 1985-06-11 Alza Corporation Drug dispenser comprising wall formed of semipermeable member and enteric member

Also Published As

Publication number Publication date
DK175532B1 (da) 2004-11-22
DE3687799D1 (de) 1993-04-01
DK48586A (da) 1986-08-02
ES551505A0 (es) 1988-02-16
US4685918A (en) 1987-08-11
DE3687799T2 (de) 1993-07-01
IE59888B1 (en) 1994-04-20
EP0190969A2 (en) 1986-08-13
HK102995A (en) 1995-06-30
CY1861A (en) 1996-04-05
ATE85889T1 (de) 1993-03-15
CA1264133A (en) 1990-01-02
DK48586D0 (da) 1986-01-31
EP0190969B1 (en) 1993-02-24
IE860213L (en) 1986-08-01
JPS61185272A (ja) 1986-08-18
JPH0655666B2 (ja) 1994-07-27
EP0190969A3 (en) 1987-11-04

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20071029