ES8707262A1 - Procedimiento para la preparacion de un compuesto peptidico util para la fabricacion de vacunas contra la malaria y parala deteccion de enfermedades paludicas. - Google Patents
Procedimiento para la preparacion de un compuesto peptidico util para la fabricacion de vacunas contra la malaria y parala deteccion de enfermedades paludicas.Info
- Publication number
- ES8707262A1 ES8707262A1 ES555886A ES555886A ES8707262A1 ES 8707262 A1 ES8707262 A1 ES 8707262A1 ES 555886 A ES555886 A ES 555886A ES 555886 A ES555886 A ES 555886A ES 8707262 A1 ES8707262 A1 ES 8707262A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- detection
- well
- composition useful
- diagnostic kits
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 238000009007 Diagnostic Kit Methods 0.000 title abstract 2
- 238000001514 detection method Methods 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 229940124735 malaria vaccine Drugs 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 abstract 1
- DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 abstract 1
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 abstract 1
- 235000004279 alanine Nutrition 0.000 abstract 1
- 235000009582 asparagine Nutrition 0.000 abstract 1
- 229960001230 asparagine Drugs 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56905—Protozoa
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
- C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
- C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
- C08G69/10—Alpha-amino-carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Polymers & Plastics (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS PEPTIDICOS. COMPRENDE LA SINTESIS DE UN TETRAPEPTIDO PROTEGIDO EN EL GRUPO AMINO TERMINAL DE ASN, DE FORMULA X-ASN-ALA-ASN-PRO-OH, EN LA QUE X ES UN GRUPO PROTECTOR ACIDOLABIL, EN UN DISOLVENTE ORGANICO INERTE, A UNA TEMPERATURA COMPRENDIDA ENTRE C10JC Y 40JC; ACTIVACION DEL TETRAPEPTIDO POR TRATAMIENTO CON DERIVADOS FENOL HALOGENADOS; ALEJAMIENTO DEL GRUPO PROTECTOR AMINO POR ACIDOLISIS; POLICONDENSACION DEL TETRAPEPTIDO ASI OBTENIDO, EN PRESENCIA DE UNA BASE ORGANICA; Y SEPARACION DE LA MEZCLA PEPTIDICA DE FORMULA H-(ASN-ALA-ASN-PRO)N-OH, EN LA QUE N VALE 10-100, ASI OBTENIDA. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA LA PREPARACION DE VACUNAS CONTRA LA MALARIA Y LA DETECCION DE ENFERMEDADES PALUDICAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT21718/85A IT1187710B (it) | 1985-07-25 | 1985-07-25 | Composizione peptidica utile per la preparazione di vaccini per la malaria e di kit diagnostici per la determinazione di affezioni malariche |
Publications (2)
Publication Number | Publication Date |
---|---|
ES555886A0 ES555886A0 (es) | 1987-07-16 |
ES8707262A1 true ES8707262A1 (es) | 1987-07-16 |
Family
ID=11185878
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES555886A Expired ES8707262A1 (es) | 1985-07-25 | 1986-05-27 | Procedimiento para la preparacion de un compuesto peptidico util para la fabricacion de vacunas contra la malaria y parala deteccion de enfermedades paludicas. |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0209643B1 (es) |
JP (1) | JPH0772198B2 (es) |
AR (1) | AR247404A1 (es) |
AT (1) | ATE77957T1 (es) |
BR (1) | BR8603729A (es) |
CA (1) | CA1339590C (es) |
DE (1) | DE3685917T2 (es) |
ES (1) | ES8707262A1 (es) |
IN (1) | IN162809B (es) |
IT (1) | IT1187710B (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1196501B (it) * | 1986-07-16 | 1988-11-16 | Eniricerche Spa | Polipeptide utile per la preparazione di vaccini per la malaria e di kits diagnostici per la determinazione di affezioni malariche |
US5225530A (en) * | 1986-07-16 | 1993-07-06 | Eniricerche S.P.A. | Polypeptide useful for the preparation of antimalarial vaccines and of diagnostic kits for the detection of malarial affections |
IT1198233B (it) * | 1986-12-23 | 1988-12-21 | Eniricerche Spa | Metodo per la determinazione di anticorpi antisporozoita di p. falciparum nel sangue umano |
CA1329124C (en) * | 1987-02-02 | 1994-05-03 | Jerald C. Sadoff | Conjugate malaria vaccine |
IT1223301B (it) * | 1987-09-11 | 1990-09-19 | Eniricerche Spa | Polipeptidi sequenziali immunologicamente attivi |
IT1226728B (it) * | 1988-08-05 | 1991-02-05 | Eniricerche Spa | Coniugato peptidico immunologicamente attivo utile come vaccino antimalaria e metodo di immunizzazione impiegante lo stesso |
US5231168A (en) * | 1988-09-16 | 1993-07-27 | Statens Seruminstitut | Malaria antigen |
EP0378881B1 (en) * | 1989-01-17 | 1993-06-09 | ENIRICERCHE S.p.A. | Synthetic peptides and their use as universal carriers for the preparation of immunogenic conjugates suitable for the development of synthetic vaccines |
IT1237764B (it) * | 1989-11-10 | 1993-06-17 | Eniricerche Spa | Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici. |
IT1241395B (it) * | 1990-04-02 | 1994-01-10 | Eniricerche Spa | Composti immunogenici,il procedimento per la loro sintesi e loro impiego per la preparazione di vaccini antimalaria |
JP2586960B2 (ja) * | 1991-01-25 | 1997-03-05 | 日産建設株式会社 | 岩盤竪坑築造のための無発破式工法及びこの工法に使用する装置 |
JPH10204358A (ja) * | 1996-11-21 | 1998-08-04 | Brother Ind Ltd | ホットメルト型固体インク |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4707357A (en) * | 1984-06-26 | 1987-11-17 | The United States Of America As Represented By The Secretary Of The Army | Immunologically active peptides capable of inducing immunization against malaria and genes encoding therefor |
CN86100979A (zh) * | 1985-02-07 | 1986-12-17 | 史密丝克莱恩贝克曼公司 | 疟疾疫苗的制备方法 |
ATE78869T1 (de) * | 1985-02-07 | 1992-08-15 | Smithkline Beecham Corp | Malaria-impfstoff. |
PT82282B (pt) * | 1985-03-28 | 1988-02-17 | Univ New York | Processo de preparacao de um conjugado de proteina de suporte-antigeno imunogenico para uso como vacina contra malaria |
-
1985
- 1985-07-25 IT IT21718/85A patent/IT1187710B/it active
-
1986
- 1986-04-16 EP EP86105223A patent/EP0209643B1/en not_active Expired - Lifetime
- 1986-04-16 DE DE8686105223T patent/DE3685917T2/de not_active Expired - Fee Related
- 1986-04-16 AT AT86105223T patent/ATE77957T1/de not_active IP Right Cessation
- 1986-04-18 IN IN289/MAS/86A patent/IN162809B/en unknown
- 1986-05-27 ES ES555886A patent/ES8707262A1/es not_active Expired
- 1986-05-28 AR AR86304136A patent/AR247404A1/es active
- 1986-07-24 CA CA000514627A patent/CA1339590C/en not_active Expired - Fee Related
- 1986-07-24 JP JP61172932A patent/JPH0772198B2/ja not_active Expired - Lifetime
- 1986-07-25 BR BR8603729A patent/BR8603729A/pt unknown
Also Published As
Publication number | Publication date |
---|---|
IN162809B (es) | 1988-07-09 |
JPH0772198B2 (ja) | 1995-08-02 |
ES555886A0 (es) | 1987-07-16 |
JPS6229597A (ja) | 1987-02-07 |
EP0209643A2 (en) | 1987-01-28 |
DE3685917D1 (de) | 1992-08-13 |
IT8521718A0 (it) | 1985-07-25 |
ATE77957T1 (de) | 1992-07-15 |
IT1187710B (it) | 1987-12-23 |
EP0209643B1 (en) | 1992-07-08 |
CA1339590C (en) | 1997-12-16 |
AR247404A1 (es) | 1994-12-29 |
DE3685917T2 (de) | 1993-02-25 |
EP0209643A3 (en) | 1988-07-06 |
BR8603729A (pt) | 1987-03-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20041102 |