ES8704003A1 - Improvements relating to biotransformation reactions. - Google Patents

Improvements relating to biotransformation reactions.

Info

Publication number
ES8704003A1
ES8704003A1 ES548668A ES548668A ES8704003A1 ES 8704003 A1 ES8704003 A1 ES 8704003A1 ES 548668 A ES548668 A ES 548668A ES 548668 A ES548668 A ES 548668A ES 8704003 A1 ES8704003 A1 ES 8704003A1
Authority
ES
Spain
Prior art keywords
biological material
fixation
liquid permeable
suspension
biomass
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES548668A
Other languages
Spanish (es)
Other versions
ES548668A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Manchester Institute of Science and Technology (UMIST)
University of Manchester
Original Assignee
University of Manchester Institute of Science and Technology (UMIST)
University of Manchester
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Manchester Institute of Science and Technology (UMIST), University of Manchester filed Critical University of Manchester Institute of Science and Technology (UMIST)
Publication of ES8704003A1 publication Critical patent/ES8704003A1/en
Publication of ES548668A0 publication Critical patent/ES548668A0/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/12—Apparatus for enzymology or microbiology with sterilisation, filtration or dialysis means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/14—Rotation or movement of the cells support, e.g. rotated hollow fibers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/02—Photobioreactors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/16—Particles; Beads; Granular material; Encapsulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M31/00—Means for providing, directing, scattering or concentrating light
    • C12M31/08—Means for providing, directing, scattering or concentrating light by conducting or reflecting elements located inside the reactor or in its structure

Abstract

A method of effecting biotransformations comprises, as a first step, the fixation of biological material from suspension by passing suspension through a liquid permeable member which is capable of filtering the biological material. The liquid permeable member is an integral body or a composite body whose components are maintained in a substantially fixed relationship to each other. The biological material may comprise living or biochemically active cells and/or tissues and/or particles which themselves comprise pre-immobilised biocatalysts. After fixation, the biochemical transformation is effected by contacting the biological material supported on the member with a liquid and/or gaseous medium to form a product and/or biomass. Finally, the product is recovered and/or the biomass is harvested. Various apparatus for effecting the fixation of the biological material are described and generally incorporate means for establishing a relative velocity between the liquid permeable body and the suspension so as to effect the filtration. Also described are reactor systems comprising biological material which has been entrapped by fixation on a liquid permeable support body. The invention may be applied to the fixation of plant cells for growth into "plantlets" (i.e. micropropagation).
ES548668A 1984-11-07 1985-11-07 Improvements relating to biotransformation reactions. Expired ES8704003A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848428085A GB8428085D0 (en) 1984-11-07 1984-11-07 Immobilisation of biological material

Publications (2)

Publication Number Publication Date
ES8704003A1 true ES8704003A1 (en) 1987-03-01
ES548668A0 ES548668A0 (en) 1987-03-01

Family

ID=10569357

Family Applications (1)

Application Number Title Priority Date Filing Date
ES548668A Expired ES8704003A1 (en) 1984-11-07 1985-11-07 Improvements relating to biotransformation reactions.

Country Status (10)

Country Link
EP (1) EP0231193A1 (en)
JP (1) JPS62500701A (en)
KR (1) KR880700058A (en)
AU (1) AU5096785A (en)
DK (1) DK318686A (en)
ES (1) ES8704003A1 (en)
GB (2) GB8428085D0 (en)
NO (1) NO862698D0 (en)
WO (1) WO1986002944A1 (en)
ZA (1) ZA858584B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8523328D0 (en) * 1985-09-20 1985-10-23 Atomic Energy Authority Uk Biochemical reactor
GB8523327D0 (en) * 1985-09-20 1985-10-23 Atomic Energy Authority Uk Cells
US4857464A (en) * 1986-02-21 1989-08-15 Bio-Rational Technologies, Inc. Mist cultivation of cells
US4861725A (en) * 1988-03-29 1989-08-29 Liau Ming Y Mammalian cell culture apparatus
DE3932633C1 (en) * 1989-09-29 1991-04-18 Dr. Mueller-Lierheim Ag, 8033 Planegg, De
GB8928851D0 (en) * 1989-12-21 1990-02-28 Davies Simon P Growth of biological material
DE10010950A1 (en) * 2000-03-06 2001-09-20 Sefar Ag Rueschlikon Disposable bioreactor for cultivation of dendritic cells used in immuno therapy, comprises a substrate-carrying organic material located in a pouch
US20100105125A1 (en) * 2008-10-24 2010-04-29 Bioprocessh20 Llc Systems, apparatuses and methods for cultivating microorganisms and mitigation of gases
BRPI0919934A2 (en) * 2008-10-24 2015-08-11 Bioprocess H20 Llc Container, method and system for cultivating microorganisms, and method for cultivating free oxygen during cultivation of microorganisms
EP3860955A4 (en) * 2018-10-01 2022-07-13 The Regents Of The University Of Michigan Bioreactor insert and biofilm support, related apparatus and related methods

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3997396A (en) * 1973-07-02 1976-12-14 Monsanto Company Method for the in vitro propagation and maintenance of cells
GB2055397B (en) * 1979-06-05 1983-02-02 Univ Strathclyde Rotating biological film contactor
DE3005605A1 (en) * 1980-02-15 1981-10-01 Sartorius GmbH, 3400 Göttingen Antigen extn. from cell suspension - by membrane and ultrafiltration stages
CH651587A5 (en) * 1980-11-18 1985-09-30 Chemap Ag METHOD AND DEVICE FOR SUBMERSE CELL CULTURE.
CH647547A5 (en) * 1982-02-12 1985-01-31 Chemap Ag METHOD AND DEVICE FOR BREEDING MICROORGANISMS.

Also Published As

Publication number Publication date
NO862698L (en) 1986-07-03
NO862698D0 (en) 1986-07-03
KR880700058A (en) 1988-02-15
JPS62500701A (en) 1987-03-26
EP0231193A1 (en) 1987-08-12
GB2168721B (en) 1989-04-19
DK318686D0 (en) 1986-07-04
GB2168721A (en) 1986-06-25
ES548668A0 (en) 1987-03-01
GB8527452D0 (en) 1985-12-11
WO1986002944A1 (en) 1986-05-22
AU5096785A (en) 1986-06-03
GB8428085D0 (en) 1984-12-12
ZA858584B (en) 1986-07-30
DK318686A (en) 1986-07-04

Similar Documents

Publication Publication Date Title
WO1997012960A3 (en) Solid support for use in cell cultivation, especially for the cultivation of liver cells, biological reactor containing said solid support and the use thereof in a bio-artificial liver system
DE2915135C2 (en)
DK1097988T3 (en) Method for cell culture in monolayers
EP0256751A3 (en) Transformation, somatic embryogenesis and whole plant regeneration method for glycine species
EP0764719A3 (en) Methods for animal cell culture
ES8704003A1 (en) Improvements relating to biotransformation reactions.
EP0145197A3 (en) Method of culturing freeze-dried microorganisms
AU7387287A (en) Process for producing biologically active plasminogen activator
ES8800348A1 (en) Process for preparing oxirane-bearing polymer carriers for immobilizing enzymes and other materials bearing active hydrogen, and oxirane-bearing polymer carriers.
DE3127979C2 (en) Use of a specific cholesterase to hydrolyze cholesterol fatty acid esters
EP0241578A3 (en) Process for replicating bone marrow in vitro
EP0112154A3 (en) Method for culturing living cells
KR910020171A (en) Method for producing L-(-)-carnitine by biocatalyst from crotonovebetaine and protein strain used in the method
FR2526442B1 (en) PRODUCTION OF GLUCOSE DEHYDROGENASE AND USE OF THE ENZYME OBTAINED IN THE ENZYMATIC SYNTHESIS OF L-CARNITINE
Kiy et al. Production of lysosomal enzymes by continuous high-cell-density fermentation of the ciliated protozoon Tetrahymena thermophila in a perfused bioreactor
AU584774B2 (en) Process for regenerating corn
US4394450A (en) Method for purification of uricase
EP0260497A3 (en) Lectin like protein substance having anti-tumor action
JPS5682099A (en) Production of glutathion
JPS5675095A (en) Preparation of heat-resistant acetic acid kinase
SU806760A1 (en) Method of producing cultural filtrate of basidial russula decolorans fungus
DE3211279A1 (en) Method for the immobilisation of microbial cells with glucose isomerase activity
JPS56154992A (en) Heat-resistant immobilized acetate kinase
RU92009231A (en) METHOD OF OBTAINING SUPEROXIDDISMUTASE
Ley Potential use of the bioreactor to determine effects of microgravity and other environmental parameters on growth of hybridoma cells