ES8703433A1 - Un procedimiento para preparar un derivado triciclico de pi-ridazinona - Google Patents
Un procedimiento para preparar un derivado triciclico de pi-ridazinonaInfo
- Publication number
- ES8703433A1 ES8703433A1 ES548413A ES548413A ES8703433A1 ES 8703433 A1 ES8703433 A1 ES 8703433A1 ES 548413 A ES548413 A ES 548413A ES 548413 A ES548413 A ES 548413A ES 8703433 A1 ES8703433 A1 ES 8703433A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- compound
- formula
- heterocyclic compounds
- piridazinone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/36—Benzo-cinnolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR UN DERIVADO TRICICLICO DE PIRIDAZINONA. CONSISTE EN HACER REACCIONAR A UN COMPUESTO DE FORMULA (II) CON HIDRAZINA O UN EQUIVALENTE QUIMICO DE LA MISMA EN SOLUCION ACUOSA ACIDA, Y A LA DE TEMPERATURA DE REFLUJO, PARA OBTENER UN COMPUESTO DE FORMULA (I) Y SUS SALES FARMACEUTICAMENTE ACEPTABLES DEL MISMO. SIENDO: R, H O ALQUILO DE C 1 A 2; R1, H, ALQUILO DE C 1 A 6, ALCOXI DE C 1 A 6 Y OTROS; R2, H O ALQUILO DE C 1 A 6; R3, H; R0, H U OH; L, UN GRUPO LABIL (AMINO E HIDROXI); R13, R1; Y N, 1 O 2. SE UTILIZAN COMO AGENTES INOTROPICOS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB848427688A GB8427688D0 (en) | 1984-11-01 | 1984-11-01 | Heterocyclic compounds |
GB848427687A GB8427687D0 (en) | 1984-11-01 | 1984-11-01 | Heterocyclic compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8703433A1 true ES8703433A1 (es) | 1987-02-16 |
ES548413A0 ES548413A0 (es) | 1987-02-16 |
Family
ID=26288399
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES548413A Expired ES8703433A1 (es) | 1984-11-01 | 1985-10-31 | Un procedimiento para preparar un derivado triciclico de pi-ridazinona |
Country Status (8)
Country | Link |
---|---|
US (1) | US4755511A (es) |
EP (1) | EP0181145B1 (es) |
AU (1) | AU578496B2 (es) |
DE (1) | DE3575720D1 (es) |
DK (1) | DK496885A (es) |
ES (1) | ES8703433A1 (es) |
GR (1) | GR852642B (es) |
PT (1) | PT81404B (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4861773A (en) * | 1986-04-28 | 1989-08-29 | Smith Kline & French Laboratories Limited | Heterocyclic compounds |
WO1989004306A1 (en) * | 1987-11-02 | 1989-05-18 | Yoshitomi Pharmaceutical Industries, Ltd. | Fused pyridazine compounds and their medicinal uses |
US5153194A (en) * | 1988-09-21 | 1992-10-06 | Yoshitomi Pharmaceutical Industries, Ltd. | Thienocycloheptapyridazine compounds and their pharmaceutical use |
US20100210590A1 (en) * | 1995-09-27 | 2010-08-19 | Northwestern University | Compositions and treatments for seizure-related disorders |
WO2006050389A2 (en) * | 2004-11-02 | 2006-05-11 | Northwestern University | Pyridazine compounds, compositions and methods |
CA2589102C (en) * | 2004-11-02 | 2013-08-13 | Northwestern University | Pyridazine compounds and methods for using the compounds to treat inflammatory diseases |
CA2650711A1 (en) * | 2006-04-28 | 2007-11-08 | Northwestern University | Compositions and treatments using pyridazine compounds and cholinesterase inhibitors |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3464988A (en) * | 1968-01-11 | 1969-09-02 | Bristol Myers Co | 3-hydrazinobenzo(h)cinnolines and 3 - hydrazinobenzocyclohepta-(5,6-c)pyridazines |
US4602019A (en) * | 1983-04-22 | 1986-07-22 | Warner-Lambert Company | Indeno[1,2-c]pyridazin-3-one derivatives useful as cardiotonic and antihypertensive agents |
GB2164643B (en) * | 1984-07-27 | 1988-11-02 | Boehringer Biochemia Srl | Tricyclic dihydropyridazinones and pharmaceutical compositions containing them |
JPH06763B2 (ja) * | 1984-08-28 | 1994-01-05 | 吉富製薬株式会社 | ベンゾ〔h〕シンノリン誘導体 |
-
1985
- 1985-10-28 AU AU49110/85A patent/AU578496B2/en not_active Ceased
- 1985-10-29 DK DK496885A patent/DK496885A/da not_active Application Discontinuation
- 1985-10-30 DE DE8585307838T patent/DE3575720D1/de not_active Expired - Lifetime
- 1985-10-30 PT PT81404A patent/PT81404B/pt not_active IP Right Cessation
- 1985-10-30 EP EP85307838A patent/EP0181145B1/en not_active Expired - Lifetime
- 1985-10-31 ES ES548413A patent/ES8703433A1/es not_active Expired
- 1985-11-01 GR GR852642A patent/GR852642B/el unknown
-
1987
- 1987-09-22 US US07/099,709 patent/US4755511A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU578496B2 (en) | 1988-10-27 |
ES548413A0 (es) | 1987-02-16 |
EP0181145A3 (en) | 1986-12-30 |
PT81404A (en) | 1985-11-01 |
GR852642B (es) | 1986-03-04 |
US4755511A (en) | 1988-07-05 |
EP0181145B1 (en) | 1990-01-31 |
AU4911085A (en) | 1986-05-08 |
PT81404B (pt) | 1988-02-17 |
DK496885D0 (da) | 1985-10-29 |
EP0181145A2 (en) | 1986-05-14 |
DE3575720D1 (de) | 1990-03-08 |
DK496885A (da) | 1986-05-02 |
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