ES8702441A1 - Un metodo de producir una solucion acuosa, muy concentrada, de gamma-interferon de humano - Google Patents

Un metodo de producir una solucion acuosa, muy concentrada, de gamma-interferon de humano

Info

Publication number
ES8702441A1
ES8702441A1 ES539736A ES539736A ES8702441A1 ES 8702441 A1 ES8702441 A1 ES 8702441A1 ES 539736 A ES539736 A ES 539736A ES 539736 A ES539736 A ES 539736A ES 8702441 A1 ES8702441 A1 ES 8702441A1
Authority
ES
Spain
Prior art keywords
production
solubilized protein
protein
highly solubilized
highly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES539736A
Other languages
English (en)
Other versions
ES539736A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP59010858A external-priority patent/JPS60155137A/ja
Priority claimed from JP60002586A external-priority patent/JPH064680B2/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of ES8702441A1 publication Critical patent/ES8702441A1/es
Publication of ES539736A0 publication Critical patent/ES539736A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/57—IFN-gamma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

METODO PARA PREPARAR UNA SOLUCION ACUOSA MUY CONCENTRADA DE GAMMA-INTERFERON HUMANO. COMPRENDE LA SEPARACION DE UN AGENTE DE DESNATURALIZACION DE PROTEINAS DE UNA SOLUCION ACUOSA DE G-INTERFERON QUE CONTIENE DICHO AGENTE, ENVEJECIMIENTO <IN SITU> DE LA SOLUCION RESULTANTE A TEMPERATURAS ENTRE 0 Y 40JC, Y CONCENTRACION DE LA MISMA POR ULTRAFILTRACION. APLICABLE PARA LA FABRICACION DE PREPARACIONES FARMACEUTICAS.
ES539736A 1984-01-23 1985-01-22 Un metodo de producir una solucion acuosa, muy concentrada, de gamma-interferon de humano Expired ES8702441A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59010858A JPS60155137A (ja) 1984-01-23 1984-01-23 高濃度ヒトγ型インタ−フエロン水溶液の製造法
JP60002586A JPH064680B2 (ja) 1985-01-09 1985-01-09 高濃度ヒトγ型インターフェロンフラグメント水溶液の製造法

Publications (2)

Publication Number Publication Date
ES8702441A1 true ES8702441A1 (es) 1987-01-01
ES539736A0 ES539736A0 (es) 1987-01-01

Family

ID=26336003

Family Applications (1)

Application Number Title Priority Date Filing Date
ES539736A Expired ES8702441A1 (es) 1984-01-23 1985-01-22 Un metodo de producir una solucion acuosa, muy concentrada, de gamma-interferon de humano

Country Status (10)

Country Link
EP (1) EP0150066A3 (es)
KR (1) KR850005456A (es)
AU (1) AU3801785A (es)
CA (1) CA1255220A (es)
DK (1) DK28885A (es)
ES (1) ES8702441A1 (es)
GR (1) GR850157B (es)
IL (2) IL74094A0 (es)
NZ (1) NZ210896A (es)
PT (1) PT79853B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE8009110U1 (de) * 1980-04-02 1980-06-26 Recaro Gmbh & Co, 7312 Kirchheim Armlehne fuer einen fahrzeugsitz
DE3618817A1 (de) * 1986-06-04 1987-12-10 Behringwerke Ag Verfahren zur gewinnung aktiver proteine aus einer biologisch inaktiven form
US4961969A (en) * 1987-05-11 1990-10-09 Cetus Corporation Process for recovering microbially produced interferon-β
CA1340586C (en) * 1988-09-23 1999-06-08 Cetus Corporation Process for recovering microbially produced interferon-beta

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7404589A (nl) * 1974-04-03 1975-10-07 Stichting Rega V Z W Werkwijze voor het stabiliseren van interferon.
NL7404590A (nl) * 1974-04-03 1975-10-07 Stichting Rega V Z W Werkwijze voor het reactiveren van interferon.
US6936694B1 (en) * 1982-05-06 2005-08-30 Intermune, Inc. Manufacture and expression of large structural genes
JPS59500996A (ja) * 1982-06-07 1984-06-07 セルテク　リミテツド キモシンの生産方法
JPS6079000A (ja) * 1983-10-04 1985-05-04 Takeda Chem Ind Ltd ヒトγ型インタ−フエロン単量体の製造法

Also Published As

Publication number Publication date
GR850157B (es) 1985-05-21
EP0150066A3 (en) 1986-09-17
IL74094A0 (en) 1985-04-30
PT79853B (en) 1986-12-15
NZ210896A (en) 1988-02-29
DK28885A (da) 1985-07-24
AU3801785A (en) 1985-08-01
CA1255220A (en) 1989-06-06
ES539736A0 (es) 1987-01-01
PT79853A (en) 1985-02-01
KR850005456A (ko) 1985-08-26
IL74093A0 (en) 1985-04-30
EP0150066A2 (en) 1985-07-31
DK28885D0 (da) 1985-01-22

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19960603