ES8608481A1 - Benzamide derivatives - Google Patents
Benzamide derivativesInfo
- Publication number
- ES8608481A1 ES8608481A1 ES540121A ES540121A ES8608481A1 ES 8608481 A1 ES8608481 A1 ES 8608481A1 ES 540121 A ES540121 A ES 540121A ES 540121 A ES540121 A ES 540121A ES 8608481 A1 ES8608481 A1 ES 8608481A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- compound
- hydroxy
- image
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention relates to a process for the preparation of 2-hydroxy-5-{1-hydroxy-2-[(1-methyl-3-phenylpropyl)-amino]ethyl}benzamide of the formula < IMAGE > and pharmaceutically acceptable acid addition salts thereof which comprises hydrogenating 2-hydroxy-5-{1-hydroxy-2-[(1-phenyl-but-1-ene-3-ylidene)imino]ethyl}be nzamide of the formula < IMAGE > and, if desired, converting the compound of the formula I thus obtained into a pharmaceutically acceptable acid addition salt. The new compound of the formula V may be prepared by reacting the compound of the formula < IMAGE > with 1-phenyl-2-butene-3-one of the formula < IMAGE > The compound of the formula II may be, in turn, prepared by catalytic hydrogenation of the compound of the formula
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU23484A HU190867B (en) | 1984-01-20 | 1984-01-20 | Process for preparing 2-hydroxy-5-/1-hydroxy-2-/1-methyl-3-phenyl-propyl/-amino/ethyl/-benzamide and pharmaceutically acceptable salts thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8608481A1 true ES8608481A1 (en) | 1986-07-16 |
| ES540121A0 ES540121A0 (en) | 1986-07-16 |
Family
ID=10948617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES540121A Expired ES8608481A1 (en) | 1984-01-20 | 1985-01-18 | Benzamide derivatives |
Country Status (18)
| Country | Link |
|---|---|
| JP (1) | JPS60231639A (en) |
| AT (1) | AT390612B (en) |
| CA (1) | CA1239938A (en) |
| CH (1) | CH662810A5 (en) |
| CS (1) | CS249536B2 (en) |
| DD (1) | DD228245A5 (en) |
| DE (1) | DE3501582A1 (en) |
| DK (1) | DK26185A (en) |
| ES (1) | ES8608481A1 (en) |
| FI (1) | FI83635C (en) |
| FR (1) | FR2558465B1 (en) |
| GB (1) | GB2152931B (en) |
| HU (1) | HU190867B (en) |
| NL (1) | NL8500119A (en) |
| NO (1) | NO165918C (en) |
| PT (1) | PT79844B (en) |
| SE (1) | SE8500236L (en) |
| SU (1) | SU1521281A3 (en) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1247370A (en) * | 1968-12-31 | 1971-09-22 | Allen & Hanburys Ltd | Glyoxals and production thereof |
| ZA794872B (en) * | 1978-09-20 | 1980-11-26 | Schering Corp | A phenylalkylaminoethylsalicylamide,its preparation and pharmaceutical compositions containing it |
-
1984
- 1984-01-20 HU HU23484A patent/HU190867B/en not_active IP Right Cessation
- 1984-12-17 CH CH598584A patent/CH662810A5/en not_active IP Right Cessation
-
1985
- 1985-01-18 SU SU853837675A patent/SU1521281A3/en active
- 1985-01-18 DD DD27264985A patent/DD228245A5/en not_active IP Right Cessation
- 1985-01-18 AT AT11685A patent/AT390612B/en not_active IP Right Cessation
- 1985-01-18 NO NO850225A patent/NO165918C/en unknown
- 1985-01-18 DE DE19853501582 patent/DE3501582A1/en not_active Withdrawn
- 1985-01-18 FR FR8500702A patent/FR2558465B1/en not_active Expired
- 1985-01-18 CS CS37785A patent/CS249536B2/en unknown
- 1985-01-18 DK DK26185A patent/DK26185A/en not_active Application Discontinuation
- 1985-01-18 CA CA000472445A patent/CA1239938A/en not_active Expired
- 1985-01-18 ES ES540121A patent/ES8608481A1/en not_active Expired
- 1985-01-18 FI FI850229A patent/FI83635C/en not_active IP Right Cessation
- 1985-01-18 PT PT7984485A patent/PT79844B/en unknown
- 1985-01-18 JP JP597885A patent/JPS60231639A/en active Pending
- 1985-01-18 NL NL8500119A patent/NL8500119A/en not_active Application Discontinuation
- 1985-01-18 GB GB08501246A patent/GB2152931B/en not_active Expired
- 1985-06-06 SE SE8500236A patent/SE8500236L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| FI83635C (en) | 1991-08-12 |
| FI83635B (en) | 1991-04-30 |
| DE3501582A1 (en) | 1985-08-01 |
| CH662810A5 (en) | 1987-10-30 |
| HUT36779A (en) | 1985-10-28 |
| DD228245A5 (en) | 1985-10-09 |
| JPS60231639A (en) | 1985-11-18 |
| FR2558465B1 (en) | 1988-08-26 |
| NL8500119A (en) | 1985-08-16 |
| SE8500236D0 (en) | 1985-01-18 |
| ES540121A0 (en) | 1986-07-16 |
| SU1521281A3 (en) | 1989-11-07 |
| NO165918B (en) | 1991-01-21 |
| PT79844A (en) | 1985-02-01 |
| FR2558465A1 (en) | 1985-07-26 |
| CA1239938A (en) | 1988-08-02 |
| FI850229A0 (en) | 1985-01-18 |
| PT79844B (en) | 1986-10-23 |
| DK26185A (en) | 1985-07-21 |
| ATA11685A (en) | 1989-11-15 |
| HU190867B (en) | 1986-11-28 |
| NO850225L (en) | 1985-07-22 |
| CS249536B2 (en) | 1987-03-12 |
| GB2152931B (en) | 1987-03-18 |
| FI850229L (en) | 1985-07-21 |
| SE8500236L (en) | 1985-07-21 |
| DK26185D0 (en) | 1985-01-18 |
| NO165918C (en) | 1991-05-02 |
| GB8501246D0 (en) | 1985-02-20 |
| GB2152931A (en) | 1985-08-14 |
| AT390612B (en) | 1990-06-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent lapsed |
Effective date: 19960506 |