ES8607931A1 - Preparation of nifedipine sustained release pharmaceutical - Google Patents

Preparation of nifedipine sustained release pharmaceutical

Info

Publication number
ES8607931A1
ES8607931A1 ES543769A ES543769A ES8607931A1 ES 8607931 A1 ES8607931 A1 ES 8607931A1 ES 543769 A ES543769 A ES 543769A ES 543769 A ES543769 A ES 543769A ES 8607931 A1 ES8607931 A1 ES 8607931A1
Authority
ES
Spain
Prior art keywords
magnesium
fatty acid
acid ester
compsn
obtd
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES543769A
Other languages
Spanish (es)
Other versions
ES543769A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takada Seiyaku KK
Original Assignee
Takada Seiyaku KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takada Seiyaku KK filed Critical Takada Seiyaku KK
Publication of ES543769A0 publication Critical patent/ES543769A0/en
Publication of ES8607931A1 publication Critical patent/ES8607931A1/en
Expired legal-status Critical Current

Links

Abstract

Prepn. comprises preparing a fine particle compsn. obtd. by grinding mixt. of nifedipine, casein, and one or at least two substances of magnesium silicate, magnesium carbonate, dried aluminium hydroxide gel, magnesium oxide, metasilicate magnesium aluminate, synthetic hydrotarsite, and alumina magnesium hydroxide; then grinding fine article together with an enteric coating agent and an plastic agent; and dry granulating obtd. compsn. - Pren. comprises prepg. a fine particle compsn. obtd. by grinding mixt., of nifedipine, casein, and one or at least two substances of magnesium silicate, magnesium carbonate, dried aluminium hydroxide gel, magnesium oxide, metasilicate magnesium aluminate, synthetic hydrotarsite, and alumina agnesium aluminate, synthetic hydrotarsite, and alumina hydroxide, hydroxide; then grinding fine particle together wtih an enteric coating agent, an plasticising agent and higher fatty acid ester; and dry granulating obtd. compsn. - Pref. enteric coating agent is one substance or a mixt. of at least two substances of phthalic acid acetate cellulose, hydroxy propyl methyl cellulose phthalate, methyl methacrylic acid copolymer, polyvinyl acetate phthalate, cellulose acetate succinate, and styrene maleic acid copolymer. Plasticising agent is selected from polyethylene glycol, polyoxyethylene sorbitan monooleate, propylene glycol, and acethylated monoglyceride. Higher fatty acid ester is selected from cane sugar fatty acid ester, sorbitan fatty acid ester, and glycerin fatty acid ester.
ES543769A 1984-06-01 1985-05-31 Preparation of nifedipine sustained release pharmaceutical Expired ES8607931A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11089784A JPH0246008B2 (en) 1984-06-01 1984-06-01 NIFUEJIPINJIZOKUSEISEIZAINOSEIZOHOHO

Publications (2)

Publication Number Publication Date
ES543769A0 ES543769A0 (en) 1986-06-01
ES8607931A1 true ES8607931A1 (en) 1986-06-01

Family

ID=14547455

Family Applications (1)

Application Number Title Priority Date Filing Date
ES543769A Expired ES8607931A1 (en) 1984-06-01 1985-05-31 Preparation of nifedipine sustained release pharmaceutical

Country Status (2)

Country Link
JP (1) JPH0246008B2 (en)
ES (1) ES8607931A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3273809B2 (en) * 1992-06-29 2002-04-15 御木本製薬株式会社 Oil-in-water cream base
DK1067910T3 (en) * 1998-04-03 2004-10-04 Egalet As Controlled release composition
US20040234602A1 (en) 2001-09-21 2004-11-25 Gina Fischer Polymer release system
WO2003024430A1 (en) 2001-09-21 2003-03-27 Egalet A/S Morphine polymer release system
US20040151772A1 (en) 2002-11-08 2004-08-05 Egalet A/S Controlled release carvedilol compositions
ES2307003T3 (en) 2003-03-26 2008-11-16 Egalet A/S MATRIX COMPOSITIONS FOR THE CONTROLLED SUPPLY OF DRUG SUBSTANCES.
EP1610767B1 (en) 2003-03-26 2011-01-19 Egalet A/S Morphine controlled release system
NZ580972A (en) 2007-06-04 2012-02-24 Egalet Ltd Controlled release pharmaceutical compositions for prolonged effect
CA2751667C (en) 2009-02-06 2016-12-13 Egalet Ltd. Immediate release composition resistant to abuse by intake of alcohol
EP2445487A2 (en) 2009-06-24 2012-05-02 Egalet Ltd. Controlled release formulations
JP6031756B2 (en) * 2010-12-24 2016-11-24 ライオン株式会社 Granular pharmaceutical preparation and production method
CA2877183A1 (en) 2012-07-06 2014-01-09 Egalet Ltd. Abuse deterrent pharmaceutical compositions for controlled release

Also Published As

Publication number Publication date
JPS60255719A (en) 1985-12-17
JPH0246008B2 (en) 1990-10-12
ES543769A0 (en) 1986-06-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20040601