ES8607931A1 - Preparation of nifedipine sustained release pharmaceutical - Google Patents
Preparation of nifedipine sustained release pharmaceuticalInfo
- Publication number
- ES8607931A1 ES8607931A1 ES543769A ES543769A ES8607931A1 ES 8607931 A1 ES8607931 A1 ES 8607931A1 ES 543769 A ES543769 A ES 543769A ES 543769 A ES543769 A ES 543769A ES 8607931 A1 ES8607931 A1 ES 8607931A1
- Authority
- ES
- Spain
- Prior art keywords
- magnesium
- fatty acid
- acid ester
- compsn
- obtd
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Abstract
Prepn. comprises preparing a fine particle compsn. obtd. by grinding mixt. of nifedipine, casein, and one or at least two substances of magnesium silicate, magnesium carbonate, dried aluminium hydroxide gel, magnesium oxide, metasilicate magnesium aluminate, synthetic hydrotarsite, and alumina magnesium hydroxide; then grinding fine article together with an enteric coating agent and an plastic agent; and dry granulating obtd. compsn. - Pren. comprises prepg. a fine particle compsn. obtd. by grinding mixt., of nifedipine, casein, and one or at least two substances of magnesium silicate, magnesium carbonate, dried aluminium hydroxide gel, magnesium oxide, metasilicate magnesium aluminate, synthetic hydrotarsite, and alumina agnesium aluminate, synthetic hydrotarsite, and alumina hydroxide, hydroxide; then grinding fine particle together wtih an enteric coating agent, an plasticising agent and higher fatty acid ester; and dry granulating obtd. compsn. - Pref. enteric coating agent is one substance or a mixt. of at least two substances of phthalic acid acetate cellulose, hydroxy propyl methyl cellulose phthalate, methyl methacrylic acid copolymer, polyvinyl acetate phthalate, cellulose acetate succinate, and styrene maleic acid copolymer. Plasticising agent is selected from polyethylene glycol, polyoxyethylene sorbitan monooleate, propylene glycol, and acethylated monoglyceride. Higher fatty acid ester is selected from cane sugar fatty acid ester, sorbitan fatty acid ester, and glycerin fatty acid ester.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11089784A JPH0246008B2 (en) | 1984-06-01 | 1984-06-01 | NIFUEJIPINJIZOKUSEISEIZAINOSEIZOHOHO |
Publications (2)
Publication Number | Publication Date |
---|---|
ES543769A0 ES543769A0 (en) | 1986-06-01 |
ES8607931A1 true ES8607931A1 (en) | 1986-06-01 |
Family
ID=14547455
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES543769A Expired ES8607931A1 (en) | 1984-06-01 | 1985-05-31 | Preparation of nifedipine sustained release pharmaceutical |
Country Status (2)
Country | Link |
---|---|
JP (1) | JPH0246008B2 (en) |
ES (1) | ES8607931A1 (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3273809B2 (en) * | 1992-06-29 | 2002-04-15 | 御木本製薬株式会社 | Oil-in-water cream base |
DK1067910T3 (en) * | 1998-04-03 | 2004-10-04 | Egalet As | Controlled release composition |
US20040234602A1 (en) | 2001-09-21 | 2004-11-25 | Gina Fischer | Polymer release system |
WO2003024430A1 (en) | 2001-09-21 | 2003-03-27 | Egalet A/S | Morphine polymer release system |
US20040151772A1 (en) | 2002-11-08 | 2004-08-05 | Egalet A/S | Controlled release carvedilol compositions |
ES2307003T3 (en) | 2003-03-26 | 2008-11-16 | Egalet A/S | MATRIX COMPOSITIONS FOR THE CONTROLLED SUPPLY OF DRUG SUBSTANCES. |
EP1610767B1 (en) | 2003-03-26 | 2011-01-19 | Egalet A/S | Morphine controlled release system |
NZ580972A (en) | 2007-06-04 | 2012-02-24 | Egalet Ltd | Controlled release pharmaceutical compositions for prolonged effect |
CA2751667C (en) | 2009-02-06 | 2016-12-13 | Egalet Ltd. | Immediate release composition resistant to abuse by intake of alcohol |
EP2445487A2 (en) | 2009-06-24 | 2012-05-02 | Egalet Ltd. | Controlled release formulations |
JP6031756B2 (en) * | 2010-12-24 | 2016-11-24 | ライオン株式会社 | Granular pharmaceutical preparation and production method |
CA2877183A1 (en) | 2012-07-06 | 2014-01-09 | Egalet Ltd. | Abuse deterrent pharmaceutical compositions for controlled release |
-
1984
- 1984-06-01 JP JP11089784A patent/JPH0246008B2/en not_active Expired - Lifetime
-
1985
- 1985-05-31 ES ES543769A patent/ES8607931A1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
JPS60255719A (en) | 1985-12-17 |
JPH0246008B2 (en) | 1990-10-12 |
ES543769A0 (en) | 1986-06-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20040601 |