ES8607018A1 - Preparaciones medicinales solidas - Google Patents
Preparaciones medicinales solidasInfo
- Publication number
- ES8607018A1 ES8607018A1 ES544787A ES544787A ES8607018A1 ES 8607018 A1 ES8607018 A1 ES 8607018A1 ES 544787 A ES544787 A ES 544787A ES 544787 A ES544787 A ES 544787A ES 8607018 A1 ES8607018 A1 ES 8607018A1
- Authority
- ES
- Spain
- Prior art keywords
- manufacture
- pharmaceutical preparations
- solid pharmaceutical
- preparations containing
- containing dihydropyridine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
- Medicines Containing Plant Substances (AREA)
- Jellies, Jams, And Syrups (AREA)
Abstract
PROCEDIMIENTO PARA OBTENER PREPARACIONES MEDICINALES SOLIDAS A BASE DE DIHIDROPIRIDINAS. COMPRENDE: A) DILUIR 1 (P.P) DE (A) Y DE 0,01 A 1,5 (P.P) DE PVP EN DISOLVENTES ORGANICOS (ETANOL, CLORURO DE METILENO Y CLOROFORMO), ENTRE 10 Y 40JC; B) GRANULAR A LA SOLUCION DE A) CON 1 A 12 (P.P) DE PVP RETICULADA EN PRESENCIA DE (B) Y ENTRE 20 Y 30JC; C) SECAR EN VACIO EL GRANULADO HUMEDO DE B), ENTRE 20 Y 90JC Y ELIMINAR DISOLVENTES VOLATILES; D) TAMIZAR EL GRANULADO; Y E) CONFORMAR AL PRODUCTO TAMIZADO EN TABLETAS O GRAGEAS. SIENDO: (PVP), POLIVINILPIRROLIDONA; (A), DIHIDROPIRIDINA, (D.F) (I), ELEGIDA ENTRE NIFEDIPINA Y NIMODIPINA; (B), HUMECTANTES COMO LAURILSULFATO SODICO; R, FENILO (S.P) NITRO O CIANO; R1 Y R4, ALQUILO DE C 1 A 10, ALCOXI DE C 1 A 4; R2 Y R3, ALQUILO DE C 1 A 4 (S.P) CON CIANO; P.P, PARTES EN PESO; D.F, DE FORMULA; Y (S.P), SUSTITUIDO POR. SE UTILIZA EN PROCESOS DE TOXICOLOGIA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19843424553 DE3424553A1 (de) | 1984-07-04 | 1984-07-04 | Feste arzneizubereitungen mit dihydropyridinen und verfahren zu ihrer herstellung |
Publications (2)
Publication Number | Publication Date |
---|---|
ES544787A0 ES544787A0 (es) | 1986-06-16 |
ES8607018A1 true ES8607018A1 (es) | 1986-06-16 |
Family
ID=6239792
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES544787A Expired ES8607018A1 (es) | 1984-07-04 | 1985-07-02 | Preparaciones medicinales solidas |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0167909B2 (es) |
JP (1) | JPH0665644B2 (es) |
KR (1) | KR920006908B1 (es) |
AT (1) | ATE71297T1 (es) |
AU (1) | AU570328B2 (es) |
CA (1) | CA1255597A (es) |
DE (2) | DE3424553A1 (es) |
DK (1) | DK304485A (es) |
ES (1) | ES8607018A1 (es) |
FI (1) | FI852610L (es) |
GR (1) | GR851617B (es) |
HU (1) | HU197844B (es) |
IL (1) | IL75686A (es) |
PT (1) | PT80752B (es) |
ZA (1) | ZA855017B (es) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2133230A1 (es) * | 1996-01-19 | 1999-09-01 | Falicman Pablo Alber Rachitzky | Composicion de absorcion programada de granulos. |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE63321B1 (en) * | 1986-02-03 | 1995-04-05 | Elan Corp Plc | Drug delivery system |
IE59540B1 (en) * | 1987-01-09 | 1994-03-09 | Elan Corp | Sustained release capsule or tablet formulation |
US5015479A (en) * | 1987-02-02 | 1991-05-14 | Seamus Mulligan | Sustained release capsule or tablet formulation comprising a pharmaceutically acceptable dihydropyridine |
US5001139A (en) * | 1987-06-12 | 1991-03-19 | American Cyanamid Company | Enchancers for the transdermal flux of nivadipine |
US5045553A (en) * | 1987-06-24 | 1991-09-03 | Fujisawa Pharmaceutical Company, Ltd. | Pharmaceutical composition for percutaneous drug absorption and percutaneous drug absorption promoter |
US4797405A (en) * | 1987-10-26 | 1989-01-10 | Eli Lilly And Company | Stabilized pergolide compositions |
GB8903328D0 (en) * | 1989-02-14 | 1989-04-05 | Ethical Pharma Ltd | Nifedipine-containing pharmaceutical compositions and process for the preparation thereof |
HU203041B (en) * | 1989-03-14 | 1991-05-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing pharmaceutical compositions of controlled releasing factor containing nifedipin |
DE4130173A1 (de) * | 1991-09-11 | 1993-03-18 | Bayer Ag | Pharmazeutische zubereitungen mit einer speziellen kristallmodifikation des 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridindicarbonsaeure-isopropyl-(2-methoxyethyl)-esters |
GB9200607D0 (en) * | 1992-01-13 | 1992-03-11 | Ethical Pharma Ltd | Pharmaceutical compositions containing nifedipine and process for the preparation thereof |
JP4065321B2 (ja) * | 1995-03-29 | 2008-03-26 | 塩野義製薬株式会社 | 水分活性を調節したゼラチンカプセル剤 |
EP1364643A4 (en) | 2000-12-01 | 2009-07-15 | Kyowa Hakko Kogyo Kk | COMPOSITION WITH IMPROVED ORAL SOLUBILITY OR ABSORBABILITY |
DE10117049A1 (de) * | 2001-04-05 | 2002-10-17 | Novartis Ag | Zusammensetzung |
JP5072748B2 (ja) * | 2007-07-10 | 2012-11-14 | 株式会社 メドレックス | アムロジピンの安定な液剤とゼリー剤 |
IE20100799A1 (en) * | 2010-12-22 | 2012-08-01 | Eurand Pharmaceuticals Ltd | Pharmaceutical composites of poorly water soluble drugs and polymers |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1579818A (en) * | 1977-06-07 | 1980-11-26 | Yamanouchi Pharma Co Ltd | Nifedipine-containing solid preparation composition |
DE3142853A1 (de) * | 1981-10-29 | 1983-05-11 | Bayer Ag, 5090 Leverkusen | Feste arzneizubereitungen mit nifedipin und verfahren zu ihrer herstellung |
DE3270785D1 (en) * | 1981-10-29 | 1986-05-28 | Bayer Ag | Process for preparing solid fast-releasing drug formulations of dihydropyridines |
DE3318649A1 (de) * | 1983-05-21 | 1984-11-22 | Bayer Ag, 5090 Leverkusen | Zweiphasenformulierung |
JPS6038322A (ja) * | 1983-08-11 | 1985-02-27 | Fujisawa Pharmaceut Co Ltd | ジヒドロピリジンa物質含有易溶性固形製剤 |
EP0143857B1 (de) * | 1983-11-30 | 1988-04-06 | Siegfried Aktiengesellschaft | Coronartherapeutikum in Form von Weichgelatine-Kapseln |
DE3427402A1 (de) * | 1984-07-25 | 1986-01-30 | Bayer Ag, 5090 Leverkusen | Neues kombinationspraeparat, verfahren zu seiner herstellung und seine verwendung als arzneimittel |
-
1984
- 1984-07-04 DE DE19843424553 patent/DE3424553A1/de not_active Withdrawn
-
1985
- 1985-06-22 EP EP85107733A patent/EP0167909B2/de not_active Expired - Lifetime
- 1985-06-22 DE DE8585107733T patent/DE3585107D1/de not_active Expired - Lifetime
- 1985-06-22 AT AT85107733T patent/ATE71297T1/de active
- 1985-06-28 CA CA000486160A patent/CA1255597A/en not_active Expired
- 1985-06-28 AU AU44298/85A patent/AU570328B2/en not_active Ceased
- 1985-07-01 IL IL75686A patent/IL75686A/xx not_active IP Right Cessation
- 1985-07-02 ES ES544787A patent/ES8607018A1/es not_active Expired
- 1985-07-02 KR KR1019850004730A patent/KR920006908B1/ko not_active IP Right Cessation
- 1985-07-02 GR GR851617A patent/GR851617B/el unknown
- 1985-07-02 PT PT80752A patent/PT80752B/pt not_active IP Right Cessation
- 1985-07-02 FI FI852610A patent/FI852610L/fi not_active Application Discontinuation
- 1985-07-03 ZA ZA855017A patent/ZA855017B/xx unknown
- 1985-07-03 JP JP60144846A patent/JPH0665644B2/ja not_active Expired - Lifetime
- 1985-07-03 DK DK304485A patent/DK304485A/da not_active Application Discontinuation
- 1985-07-04 HU HU852604A patent/HU197844B/hu not_active IP Right Cessation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2133230A1 (es) * | 1996-01-19 | 1999-09-01 | Falicman Pablo Alber Rachitzky | Composicion de absorcion programada de granulos. |
Also Published As
Publication number | Publication date |
---|---|
HU197844B (en) | 1989-06-28 |
KR920006908B1 (ko) | 1992-08-22 |
DK304485D0 (da) | 1985-07-03 |
ES544787A0 (es) | 1986-06-16 |
PT80752B (pt) | 1987-10-20 |
ZA855017B (en) | 1986-02-26 |
IL75686A (en) | 1988-11-30 |
ATE71297T1 (de) | 1992-01-15 |
EP0167909A3 (en) | 1987-10-14 |
PT80752A (en) | 1985-08-01 |
EP0167909B1 (de) | 1992-01-08 |
AU570328B2 (en) | 1988-03-10 |
JPH0665644B2 (ja) | 1994-08-24 |
KR860000864A (ko) | 1986-02-20 |
EP0167909B2 (de) | 1994-10-19 |
FI852610L (fi) | 1986-01-05 |
IL75686A0 (en) | 1985-11-29 |
HUT41259A (en) | 1987-04-28 |
DE3585107D1 (de) | 1992-02-20 |
DE3424553A1 (de) | 1986-01-09 |
FI852610A0 (fi) | 1985-07-02 |
DK304485A (da) | 1986-01-05 |
GR851617B (es) | 1985-11-26 |
CA1255597A (en) | 1989-06-13 |
JPS6118725A (ja) | 1986-01-27 |
EP0167909A2 (de) | 1986-01-15 |
AU4429885A (en) | 1986-01-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20021003 |