ES8605584A1 - Un procedimiento para preparar foroximitina - Google Patents
Un procedimiento para preparar foroximitinaInfo
- Publication number
- ES8605584A1 ES8605584A1 ES543289A ES543289A ES8605584A1 ES 8605584 A1 ES8605584 A1 ES 8605584A1 ES 543289 A ES543289 A ES 543289A ES 543289 A ES543289 A ES 543289A ES 8605584 A1 ES8605584 A1 ES 8605584A1
- Authority
- ES
- Spain
- Prior art keywords
- foroxymithine
- medicament
- active substance
- physiologically active
- microorganisms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR FOROXIMITINA. COMPRENDE: A) CULTIVAR UN MICROORGANISMO PRODUCTOR DE LA FOROXIMITINA COMO STREPTOMYCES NITROS POREUS FERM-P 7244 O STREPTOMYCES ZAOMYCETICUS FERM-P 7243, EN UN MEDIO NUTRIENTE QUE CONTIENE FUENTES DE CARBONO Y NITROGENO Y SALES NUTRIENTES INORGANICAS, A UNA TEMPERATURA ENTRE 25J Y 35JC, PARA PRODUCIR FOROXIMITINA DE FORMULA (I) EN SOLUCION; B) FILTRAR LA SOLUCION DE A); C) ADSORBER EL FILTRADO CON CARBON ACTIVADO; D) ELUIR EL FILTRADO DE C) CON UNA SOLUCION DE ACETONA; Y E) PURIFICAR EL FILTRADO ELUIDO POR CROMATOGRAFIA LIQUIDA. SE UTILIZA COMO INHIBIDORA DE LA ENZIMA CONVERTIDORA DE LA ANGIOTENSINA Y COMO ANTIHIPERTENSORA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP59100441A JPS60246399A (ja) | 1984-05-21 | 1984-05-21 | 新生理活性物質ホルオキシミチン、その製造法および用途 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8605584A1 true ES8605584A1 (es) | 1986-03-16 |
ES543289A0 ES543289A0 (es) | 1986-03-16 |
Family
ID=14274018
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES543289A Expired ES8605584A1 (es) | 1984-05-21 | 1985-05-20 | Un procedimiento para preparar foroximitina |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0162422A2 (es) |
JP (1) | JPS60246399A (es) |
DK (1) | DK223385A (es) |
ES (1) | ES8605584A1 (es) |
GR (1) | GR851217B (es) |
HU (1) | HUT38971A (es) |
PT (1) | PT80496B (es) |
ZA (1) | ZA853779B (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115340961B (zh) * | 2022-04-26 | 2023-05-16 | 浙江师范大学 | 拮抗水稻细菌性条斑病菌的沙阿霉素链霉菌及其应用 |
-
1984
- 1984-05-21 JP JP59100441A patent/JPS60246399A/ja active Granted
-
1985
- 1985-05-14 HU HU851822A patent/HUT38971A/hu unknown
- 1985-05-17 EP EP85106066A patent/EP0162422A2/en not_active Withdrawn
- 1985-05-20 GR GR851217A patent/GR851217B/el unknown
- 1985-05-20 DK DK223385A patent/DK223385A/da not_active Application Discontinuation
- 1985-05-20 ZA ZA853779A patent/ZA853779B/xx unknown
- 1985-05-20 ES ES543289A patent/ES8605584A1/es not_active Expired
- 1985-05-21 PT PT80496A patent/PT80496B/pt unknown
Also Published As
Publication number | Publication date |
---|---|
GR851217B (es) | 1985-11-25 |
ZA853779B (en) | 1986-01-29 |
JPS60246399A (ja) | 1985-12-06 |
JPH0258280B2 (es) | 1990-12-07 |
DK223385D0 (da) | 1985-05-20 |
HUT38971A (en) | 1986-07-28 |
DK223385A (da) | 1985-11-22 |
PT80496B (en) | 1987-06-03 |
EP0162422A2 (en) | 1985-11-27 |
ES543289A0 (es) | 1986-03-16 |
PT80496A (en) | 1985-06-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU589387B2 (en) | Bicyclic heterocyclic piperazine derivatives | |
TW334432B (en) | Tricyclic amide and urea compounds | |
AP9701039A0 (en) | Derivatives of 2- (2-oxo-ethlidene)-imidazolidin-4-one. | |
NZ511707A (en) | Substituted bicyclic derivatives useful as anticancer agents | |
ES8702143A1 (es) | Un procedimiento para preparar derivados de piperazina con actividad psicotropica | |
MY107740A (en) | Saccharin derivatives useful as proteolytic enzyme inhibitors and compositions and method of use thereof | |
IL104154A0 (en) | Saccharin derivatives,their preparation and pharmaceutical compositions containing them | |
TR200201638T2 (tr) | Yeni imidazo[1,3,5]triazinonlar ve kullanımları | |
MY106202A (en) | Saccharin derivatives useful as proteolytic enzyme inhibitors and preparation thereof. | |
ES8700262A1 (es) | Un compuesto | |
ES8609272A1 (es) | Un procedimiento para preparar derivados de hidantoina | |
ES2001703A6 (es) | Procedimiento para la preparracion de derrrivados de acidos 2-(2-imidazolin -2-il)- piridin -3- carboxilicos. | |
ES8608524A1 (es) | Procedimiento para preparar 5h, 11h-pirrolo (2, 1-c)-(1, 4) benzoxazepinas sustituidas en posicion 11 | |
MY143570A (en) | Compounds useful for inhibition of farnesyl protein transferase | |
ATE69228T1 (de) | Amidabkoemmlinge. | |
ES8602631A1 (es) | Procedimiento de producir compuestos para tratar la hipertension | |
ES8605584A1 (es) | Un procedimiento para preparar foroximitina | |
IS4066A (is) | Afleiður fjölhydroxyfimmhringaefna, framleiðsla þeirra og notkun sem lyfja | |
DE69926078D1 (en) | Farnesyl-protein transferase inhibitoren | |
TR200101388T2 (tr) | Yeni pirimidin türevleri ve bunları hazırlama prosesleri | |
MD970230A (en) | Diamine ether diclavulanate and process for preparation thereof | |
ES8605583A1 (es) | Un procedimiento de producir un activador de plasminogeno monocatenario | |
ES2194207T3 (es) | Nuevas n-cianoiminas triciclicas utiles como inhibidores de la farnesil-protein-transferasa. | |
ES8706660A1 (es) | Un procedimiento para preparar (aminoalquiltio)hidroxidibenzoxepinas | |
ATE43586T1 (de) | Arphameninderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. |