ES8605532A1 - Un procedimiento para preparar derivados de aminoglicosido - Google Patents

Un procedimiento para preparar derivados de aminoglicosido

Info

Publication number
ES8605532A1
ES8605532A1 ES526703A ES526703A ES8605532A1 ES 8605532 A1 ES8605532 A1 ES 8605532A1 ES 526703 A ES526703 A ES 526703A ES 526703 A ES526703 A ES 526703A ES 8605532 A1 ES8605532 A1 ES 8605532A1
Authority
ES
Spain
Prior art keywords
processes
preparation
pharmaceutical compositions
compositions containing
aminoglycoside derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES526703A
Other languages
English (en)
Other versions
ES526703A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838310436A external-priority patent/GB8310436D0/en
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of ES8605532A1 publication Critical patent/ES8605532A1/es
Publication of ES526703A0 publication Critical patent/ES526703A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE AMINOGLICOSIDO, DE FORMULA GENERAL (I), EN LA QUE R1, R2, R3 Y R4 REPRESENTAN, AL MENOS UNO DE ELLOS UN ALCANOILO SUPERIOR-AMINO, Y LOS OTROS SON AMINO O ACILAMINO; R5 ES HIDROXI, AMINO O ACILAMINO; R6 Y R7 SON CADA UNO HIDROGENO O HIDROXI; Y R10 ES HIDROXI O FOSFONOXI, Y SUS SALES FARMACEUTICAMENTE ACEPTABLES. CONSISTE EN SOMETER UN COMPUESTO DE FORMULA GENERAL (II), EN EL QUE R1B ES AMINO, O SU DERIVADO REACTIVO EN EL GRUPO AMINO O UNA SAL DEL MISMO, A UNA REACCION DE ACILACION CON UN AGENTE ACILANTE, DE FORMULA: R-OH, EN LA QUE R ES ACILO, PARA OBTENER UN COMPUESTO DE FORMULA GENERAL (I). DE APLICACION COMO AGENTES PROFILACTICOS Y TERAPEUTICOS PARA EL TRATAMIENTO DE ENFERMEDADES INFECCIOSAS CAUSADAS POR MICROORGANISMOS PATOGENOS.
ES526703A 1982-10-25 1983-10-24 Un procedimiento para preparar derivados de aminoglicosido Expired ES8605532A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8230421 1982-10-25
GB838310436A GB8310436D0 (en) 1983-04-18 1983-04-18 Aminoglycoside derivatives

Publications (2)

Publication Number Publication Date
ES8605532A1 true ES8605532A1 (es) 1986-03-16
ES526703A0 ES526703A0 (es) 1986-03-16

Family

ID=26284217

Family Applications (2)

Application Number Title Priority Date Filing Date
ES526703A Expired ES8605532A1 (es) 1982-10-25 1983-10-24 Un procedimiento para preparar derivados de aminoglicosido
ES533059A Expired ES8506704A1 (es) 1982-10-25 1984-06-01 Un procedimiento para preparar derivados de aminoglicosido

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES533059A Expired ES8506704A1 (es) 1982-10-25 1984-06-01 Un procedimiento para preparar derivados de aminoglicosido

Country Status (8)

Country Link
US (1) US4493831A (es)
EP (1) EP0107850B1 (es)
KR (1) KR840006345A (es)
AU (1) AU567695B2 (es)
CA (1) CA1243019A (es)
DE (1) DE3376215D1 (es)
DK (1) DK468183A (es)
ES (2) ES8605532A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4656160A (en) * 1984-11-29 1987-04-07 Fujisawa Pharmaceutical Co., Ltd. Aminoglycoside derivatives
US5122601A (en) * 1990-12-07 1992-06-16 Hawaiian Sugar Planters'association Synthesis of 2,3,3',4,4'-penta-o-methylsucrose
US20020061281A1 (en) * 1999-07-06 2002-05-23 Osbakken Robert S. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
US6576224B1 (en) * 1999-07-06 2003-06-10 Sinuspharma, Inc. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
US6653456B2 (en) 2001-07-31 2003-11-25 Roche Diagnostics Corporation Site-specific aminoglycoside derivatives and their use in immunodiagnostic assays
KR100450607B1 (ko) * 2002-07-11 2004-09-30 경동제약 주식회사 가라민 유도체의 제조방법
US7794713B2 (en) * 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
US20080213274A1 (en) * 2005-10-28 2008-09-04 Sabbadini Roger A Compositions and methods for the treatment and prevention of fibrotic, inflammatory, and neovascularization conditions of the eye
US20090074720A1 (en) * 2005-10-28 2009-03-19 Sabbadini Roger A Methods for decreasing immune response and treating immune conditions
US7862812B2 (en) * 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions
WO2009152202A2 (en) * 2008-06-11 2009-12-17 Utah State University New aminoglycosides: synthesis and use as antifungals
US9669044B2 (en) 2010-12-14 2017-06-06 Utah State University Aminoglycoside and azole compositions and methods
WO2012082650A2 (en) * 2010-12-14 2012-06-21 Utah State University Aminoglycosides:synthesis and use as antifungals
US20210230203A1 (en) * 2020-01-23 2021-07-29 Utah State University Amphiphilic Kanamycin Compositions and Methods

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4160082A (en) * 1976-04-14 1979-07-03 Pfizer Inc. Intermediates for aminoglycoside antibiotics
DE2712160A1 (de) * 1977-03-19 1978-09-28 Bayer Ag Pseudotrisaccharide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DK308878A (da) * 1977-08-18 1979-02-19 Pfizer Aminoglyosidderivater og fremgangsmaader til deres fremstilling
DE2753769A1 (de) * 1977-12-02 1979-06-13 Bayer Ag 1-n-4,6-di-o-(aminoglykosyl)-1,3- diamino-cyclitol-derivate, verfahren zu ihrer herstellung sowie ihre verwendung
DE2936120A1 (de) * 1978-09-14 1980-03-27 Sandoz Ag Neue aminoglykoside, deren herstellung und deren verwendung als antimikrobielle mittel
DE7902758U1 (de) * 1979-02-01 1979-07-05 Tetra Werke Dr.Rer.Nat. Ulrich Baensch Gmbh, 4520 Melle Schwingankerpumpe
FI822671L (fi) * 1981-08-07 1983-02-08 Sandoz Ag Aminoglykosidderivat, foerfaranden foer framstaellning av dem, farmaceutiska kompositioner innehaollande dem samt anvaendning av saodana derivat som laekemedel
FI833421A (fi) * 1982-09-30 1984-03-31 Sandoz Ag Amidoglykosidderivat, foerfaranden foer deras framstaellning samt deras anvaendning

Also Published As

Publication number Publication date
AU567695B2 (en) 1987-12-03
ES533059A0 (es) 1985-07-16
DE3376215D1 (en) 1988-05-11
ES8506704A1 (es) 1985-07-16
EP0107850A1 (en) 1984-05-09
AU2005683A (en) 1984-05-03
DK468183D0 (da) 1983-10-11
US4493831A (en) 1985-01-15
KR840006345A (ko) 1984-11-29
ES526703A0 (es) 1986-03-16
CA1243019A (en) 1988-10-11
DK468183A (da) 1984-04-26
EP0107850B1 (en) 1988-04-06

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