ES8604956A1 - Procedimiento de obtencion del ester etilico del acido apo- vincaminico - Google Patents
Procedimiento de obtencion del ester etilico del acido apo- vincaminicoInfo
- Publication number
- ES8604956A1 ES8604956A1 ES549105A ES549105A ES8604956A1 ES 8604956 A1 ES8604956 A1 ES 8604956A1 ES 549105 A ES549105 A ES 549105A ES 549105 A ES549105 A ES 549105A ES 8604956 A1 ES8604956 A1 ES 8604956A1
- Authority
- ES
- Spain
- Prior art keywords
- ethyl ester
- obtention
- apovincaminic acid
- apovincaminic
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ZFCQLDAGNBFMJQ-QUCCMNQESA-N apovincaminic acid Chemical compound C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)C=C(C(O)=O)N5C2=C1 ZFCQLDAGNBFMJQ-QUCCMNQESA-N 0.000 title abstract 3
- 125000004494 ethyl ester group Chemical group 0.000 title abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 150000003927 aminopyridines Chemical class 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 235000019441 ethanol Nutrition 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000005186 trinitrobenzenes Chemical class 0.000 abstract 1
- 229940124549 vasodilator Drugs 0.000 abstract 1
- 239000003071 vasodilator agent Substances 0.000 abstract 1
Classifications
- 
        - C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
 
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Saccharide Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Priority Applications (22)
| Application Number | Priority Date | Filing Date | Title | 
|---|---|---|---|
| ES549105A ES8604956A1 (es) | 1985-11-20 | 1985-11-20 | Procedimiento de obtencion del ester etilico del acido apo- vincaminico | 
| US06/929,608 US4870178A (en) | 1985-11-20 | 1986-11-10 | Process for the obtention of the ethyl ester of the apovincaminic acid | 
| AR86305863A AR241420A1 (es) | 1985-11-20 | 1986-11-12 | Procedimiento de obtencion del ester etilico del acido apovincaminico. | 
| GB868627138A GB8627138D0 (en) | 1985-11-20 | 1986-11-13 | Obtention of ethyl ester | 
| KR1019860009752A KR900000266B1 (ko) | 1985-11-20 | 1986-11-18 | 아포빈캐미닉산(apovincaminic-acid)의 에틸에스테르의 제조방법 | 
| CH4614/86A CH667093A5 (de) | 1985-11-20 | 1986-11-19 | Verfahren zur herstellung des aethylesters der apovincamin-saeure. | 
| SU864028528A SU1435153A3 (ru) | 1985-11-20 | 1986-11-19 | Способ получени сложного этилового эфира аповинкаминовой кислоты | 
| CA000523383A CA1297878C (en) | 1985-11-20 | 1986-11-19 | Process for the obtention of the ethyl ester of the apovincaminic acid | 
| PT83775A PT83775B (pt) | 1985-11-20 | 1986-11-19 | Processo para a preparacao do ester etilico do acido apovincaminico | 
| IT48672/86A IT1198480B (it) | 1985-11-20 | 1986-11-19 | Procedimento per la preparazione dell'estere eitlico dell'acido apovincaminico | 
| CN86107896A CN1014788B (zh) | 1985-11-20 | 1986-11-19 | 制备阿朴长春蔓胺酸乙酯的方法 | 
| MX9346A MX163253B (es) | 1985-11-20 | 1986-11-19 | Procedimiento de obtencion del ester etilico del acido apovincaminico | 
| JP61276403A JPS62142176A (ja) | 1985-11-20 | 1986-11-19 | アポビンカミン酸エチルエステルの製造方法 | 
| UA4028528A UA7730A1 (uk) | 1985-11-20 | 1986-11-19 | Засіб одержання складного етілового ефіра аповінкамінової кислоти | 
| FR868616153A FR2590254B1 (fr) | 1985-11-20 | 1986-11-20 | Procede d'obtention de l'ester ethylique de l'acide apovincanimique | 
| DE19863639583 DE3639583A1 (de) | 1985-11-20 | 1986-11-20 | Verfahren zum erzeugen des apovincaminsaeureethylesters | 
| BE0/217444A BE905795A (fr) | 1985-11-20 | 1986-11-20 | Procede d'obtention de l'ester ethylique de l'acide apovincaminique. | 
| GB8627789A GB2183642B (en) | 1985-11-20 | 1986-11-20 | Process for the preparation of apovincaminic acid ethyl ester | 
| LV930644A LV5257A3 (lv) | 1985-11-20 | 1993-06-22 | Apovinakmens skabes etilestera iegusanas panemiens | 
| GEAP19931240A GEP19960315B (en) | 1985-11-20 | 1993-07-27 | Method for Production of Ethyl Ester Apovinkamine Acid | 
| LTRP908A LT2245B (lt) | 1985-11-20 | 1993-08-30 | Apovinkaminines rugsties etilo esterio gavimo budas | 
| MD94-0159A MD142C2 (ro) | 1985-11-20 | 1994-02-14 | Procedeu de obţinere a esterului acidului apovincaminic | 
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title | 
|---|---|---|---|
| ES549105A ES8604956A1 (es) | 1985-11-20 | 1985-11-20 | Procedimiento de obtencion del ester etilico del acido apo- vincaminico | 
Publications (2)
| Publication Number | Publication Date | 
|---|---|
| ES549105A0 ES549105A0 (es) | 1986-03-16 | 
| ES8604956A1 true ES8604956A1 (es) | 1986-03-16 | 
Family
ID=8490230
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date | 
|---|---|---|---|
| ES549105A Expired ES8604956A1 (es) | 1985-11-20 | 1985-11-20 | Procedimiento de obtencion del ester etilico del acido apo- vincaminico | 
Country Status (18)
| Country | Link | 
|---|---|
| US (1) | US4870178A (OSRAM) | 
| JP (1) | JPS62142176A (OSRAM) | 
| KR (1) | KR900000266B1 (OSRAM) | 
| CN (1) | CN1014788B (OSRAM) | 
| AR (1) | AR241420A1 (OSRAM) | 
| BE (1) | BE905795A (OSRAM) | 
| CA (1) | CA1297878C (OSRAM) | 
| CH (1) | CH667093A5 (OSRAM) | 
| DE (1) | DE3639583A1 (OSRAM) | 
| ES (1) | ES8604956A1 (OSRAM) | 
| FR (1) | FR2590254B1 (OSRAM) | 
| GB (2) | GB8627138D0 (OSRAM) | 
| GE (1) | GEP19960315B (OSRAM) | 
| IT (1) | IT1198480B (OSRAM) | 
| MX (1) | MX163253B (OSRAM) | 
| PT (1) | PT83775B (OSRAM) | 
| SU (1) | SU1435153A3 (OSRAM) | 
| UA (1) | UA7730A1 (OSRAM) | 
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| ES2052449A1 (es) * | 1992-12-22 | 1994-07-01 | Covex Sa | Nuevo procedimiento para la preparacion del apovincaminato de etilo. | 
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| CN1042492C (zh) * | 1991-10-31 | 1999-03-17 | 东北制药总厂 | 阿扑长春胺酸乙酯制剂的制备方法 | 
| CN1083423C (zh) * | 1999-08-24 | 2002-04-24 | 中国科学院兰州化学物理研究所 | 一种清洁的催化醇酸酯化方法 | 
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| AT291446B (de) * | 1968-11-22 | 1971-07-12 | Richter Gedeon Vegyeszet | Verfahren zur Herstellung von neuen Apovincaminsäureamiden | 
| BE790837A (fr) * | 1971-11-03 | 1973-02-15 | Richter Gedeon Vegeon Vegyesze | Nouveaux esters alcaloides utiles comme vasodilatateurs cerebraux et leur procede de preparation | 
| YU41200B (en) * | 1980-02-29 | 1986-12-31 | Lek Tovarna Farmacevtskih | Process for preparing vincamine acid esters and derivatives thereof | 
| HU187733B (en) * | 1982-06-30 | 1986-02-28 | Richter Gedeon Vegyeszeti Gyar Rt,Hu | Process for preparing apovincaminic acid derivatives | 
- 
        1985
        - 1985-11-20 ES ES549105A patent/ES8604956A1/es not_active Expired
 
- 
        1986
        - 1986-11-10 US US06/929,608 patent/US4870178A/en not_active Expired - Lifetime
- 1986-11-12 AR AR86305863A patent/AR241420A1/es active
- 1986-11-13 GB GB868627138A patent/GB8627138D0/en active Pending
- 1986-11-18 KR KR1019860009752A patent/KR900000266B1/ko not_active Expired
- 1986-11-19 JP JP61276403A patent/JPS62142176A/ja active Granted
- 1986-11-19 PT PT83775A patent/PT83775B/pt unknown
- 1986-11-19 MX MX9346A patent/MX163253B/es unknown
- 1986-11-19 CA CA000523383A patent/CA1297878C/en not_active Expired - Fee Related
- 1986-11-19 CN CN86107896A patent/CN1014788B/zh not_active Expired
- 1986-11-19 SU SU864028528A patent/SU1435153A3/ru active
- 1986-11-19 IT IT48672/86A patent/IT1198480B/it active
- 1986-11-19 UA UA4028528A patent/UA7730A1/uk unknown
- 1986-11-19 CH CH4614/86A patent/CH667093A5/de not_active IP Right Cessation
- 1986-11-20 GB GB8627789A patent/GB2183642B/en not_active Expired
- 1986-11-20 BE BE0/217444A patent/BE905795A/fr not_active IP Right Cessation
- 1986-11-20 FR FR868616153A patent/FR2590254B1/fr not_active Expired - Fee Related
- 1986-11-20 DE DE19863639583 patent/DE3639583A1/de active Granted
 
- 
        1993
        - 1993-07-27 GE GEAP19931240A patent/GEP19960315B/en unknown
 
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| ES2052449A1 (es) * | 1992-12-22 | 1994-07-01 | Covex Sa | Nuevo procedimiento para la preparacion del apovincaminato de etilo. | 
Also Published As
| Publication number | Publication date | 
|---|---|
| JPH0551590B2 (OSRAM) | 1993-08-03 | 
| KR900000266B1 (ko) | 1990-01-24 | 
| KR870004983A (ko) | 1987-06-04 | 
| IT8648672A0 (it) | 1986-11-19 | 
| US4870178A (en) | 1989-09-26 | 
| MX163253B (es) | 1992-03-24 | 
| ES549105A0 (es) | 1986-03-16 | 
| FR2590254A1 (fr) | 1987-05-22 | 
| DE3639583A1 (de) | 1987-05-27 | 
| CN86107896A (zh) | 1987-10-21 | 
| IT1198480B (it) | 1988-12-21 | 
| JPS62142176A (ja) | 1987-06-25 | 
| FR2590254B1 (fr) | 1990-05-25 | 
| GB2183642A (en) | 1987-06-10 | 
| CH667093A5 (de) | 1988-09-15 | 
| GEP19960315B (en) | 1996-07-30 | 
| BE905795A (fr) | 1987-03-16 | 
| GB8627138D0 (en) | 1986-12-10 | 
| DE3639583C2 (OSRAM) | 1992-07-30 | 
| AR241420A1 (es) | 1992-07-31 | 
| CA1297878C (en) | 1992-03-24 | 
| GB2183642B (en) | 1989-10-04 | 
| PT83775A (en) | 1986-12-01 | 
| CN1014788B (zh) | 1991-11-20 | 
| PT83775B (pt) | 1988-08-17 | 
| SU1435153A3 (ru) | 1988-10-30 | 
| GB8627789D0 (en) | 1986-12-17 | 
| UA7730A1 (uk) | 1995-12-26 | 
Similar Documents
| Publication | Publication Date | Title | 
|---|---|---|
| AU514073B2 (en) | Process for the manufacture of sodium perborate monohydrate and product obtained according to the process | |
| AU8300387A (en) | Process for production of eicosapentaenoic acid | |
| AU1678388A (en) | Process for production of acrylic acid | |
| HU908495D0 (en) | Process for the production of a-nor-steroid-3-carbonic acid derivatives | |
| ZA88449B (en) | Process for production of avermectins and cultures therefor | |
| HUT51848A (en) | Process for conservation of transpantable epitheliumshives produced in vitro | |
| EP0252716A3 (en) | Process for production of bishomo- gamma-linolenic acid and eicosapentaenoic acid | |
| EP0284176A3 (en) | Process for production of avermectins and cultures therefor | |
| ES463805A1 (es) | Un procedimiento para la preparacion de 2-nitrato de 1,3,3- 6-dianhidro-d-glucitol. | |
| HUT43853A (en) | Process for production of derivatives of cefem carbonic acid | |
| UA6330A1 (uk) | Спосіб одержання похідних бензаміда | |
| ES8604956A1 (es) | Procedimiento de obtencion del ester etilico del acido apo- vincaminico | |
| IL90674A0 (en) | Process for the preparation of 2,6-dichlorodiphenylamino-acetic acid derivatives | |
| ES2001695A6 (es) | Procedimiento para preparar esteres alquilicos de c1-c4 de acido 4-alcoxi-3-pirrolin-2-on-1-il-acetico | |
| GB2037791B (en) | Fermentation process for production of xanthan | |
| DE3665863D1 (en) | Process for the preparation of meldrum's acid | |
| AU7815087A (en) | Production of cellulose involving in vitro synthesis | |
| HU206711B (en) | Process for producing esters of dihydrolyzergic acid | |
| HUT47115A (en) | Process for producing hydroximic acid derivatives of ethers and thioethers substituted with 7-azabicyclo-heptyl group | |
| HUT48570A (en) | Process for production of derivatives of mercaptobensoic acid | |
| HUT40611A (en) | Process for production of derivatives of bensoic acid | |
| HUT61596A (en) | Process for fermentation production of d-isocitric acid | |
| PH25252A (en) | Novel microorganism and method for production of glutamic acid using the same | |
| ZA892918B (en) | Carbamate derivatives and a process for their production | |
| AU603415C (en) | Process for production of avermectins and cultures therefor |