ES8603407A1 - Procedimiento para preparar un agente farmaceutico que con- tiene un inhibidor de la enzima convertidora de angiotensina - Google Patents

Procedimiento para preparar un agente farmaceutico que con- tiene un inhibidor de la enzima convertidora de angiotensina

Info

Publication number
ES8603407A1
ES8603407A1 ES541436A ES541436A ES8603407A1 ES 8603407 A1 ES8603407 A1 ES 8603407A1 ES 541436 A ES541436 A ES 541436A ES 541436 A ES541436 A ES 541436A ES 8603407 A1 ES8603407 A1 ES 8603407A1
Authority
ES
Spain
Prior art keywords
glaucoma
treatment
mammals
mono
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES541436A
Other languages
English (en)
Other versions
ES541436A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES8603407A1 publication Critical patent/ES8603407A1/es
Publication of ES541436A0 publication Critical patent/ES541436A0/es
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/556—Angiotensin converting enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UN AGENTE FARMACEUTICO QUE CONTIENE UN INHIBIDOR DE LA ENZIMA CONVERTIDORA DE ANGIOTENSINA. CONSISTE EN HACER REACCIONAR A UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), PARA OBTENER UN COMPUESTO DE FORMULA (I) Y SUS SALES FISIOLOGICAMENTE ACEPTABLES. SIENDO R, R1, R2 Y R3, H, UN RADICAL ALIFATICO DE C 1 A 8, UN RADICAL ALICICLICO DE C 3 A 9, O UN RADICAL AROMATICO DE C 6 A 12 EVENTUALMENTE SUSTITUIDOS; R4 Y R5 CON LOS ATOMOS QUE LOS LLEVAN FORMAN UN SISTEMA HETEROCICLICO DE ANILLOS MONOCICLICO, BICICLICO, O TRICICLICO DE C 5 A 15; W, H O UN RADICAL SEPARABLE EN CONDICIONES ACIDAS, BASICAS O HIDROGENOLITICAS Y N 1 O 2. SE UTILIZAN PARA DISMINUIR LA PRESION OCULAR INTERNA EN MAMIFEROS.
ES541436A 1984-03-23 1985-03-21 Procedimiento para preparar un agente farmaceutico que con- tiene un inhibidor de la enzima convertidora de angiotensina Granted ES541436A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843410732 DE3410732A1 (de) 1984-03-23 1984-03-23 Methode zur behandlung des glaukoms

Publications (2)

Publication Number Publication Date
ES8603407A1 true ES8603407A1 (es) 1985-12-16
ES541436A0 ES541436A0 (es) 1985-12-16

Family

ID=6231422

Family Applications (1)

Application Number Title Priority Date Filing Date
ES541436A Granted ES541436A0 (es) 1984-03-23 1985-03-21 Procedimiento para preparar un agente farmaceutico que con- tiene un inhibidor de la enzima convertidora de angiotensina

Country Status (9)

Country Link
EP (1) EP0158157A1 (es)
JP (1) JPS60209527A (es)
AU (1) AU578079B2 (es)
DE (1) DE3410732A1 (es)
DK (1) DK131585A (es)
ES (1) ES541436A0 (es)
GR (1) GR850718B (es)
PT (1) PT80152B (es)
ZA (1) ZA852156B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4783444A (en) * 1984-09-17 1988-11-08 Schering Corporation Antiglaucoma compositions and methods
DE3413710A1 (de) * 1984-04-12 1985-10-24 Hoechst Ag, 6230 Frankfurt Verfahren zur behandlung der herzinsuffizienz
IT1227336B (it) * 1987-09-11 1991-04-08 Squibb & Sons Inc Composizione farmaceutica contenente un carico elevato di medicamento e procedimento per la sua preparazione
DE3818245A1 (de) * 1988-05-28 1989-12-07 Hoechst Ag Kombination von angiotensin-converting-enzyme-hemmern mit kaliumkanal-modulatoren sowie deren verwendung in arzneimitteln
DK641189A (da) * 1988-12-19 1990-06-20 Merck & Co Inc Praeparat til behandling af glaucom og fremgangsmaade til fremstilling af et saadant praeparat
DK53291D0 (da) * 1991-03-25 1991-03-25 Carlbiotech Ltd As Smaa peptider og peptidrelaterede stoffer samt farmaceutiske praeparater indeholdende saadanne forbindelser
FR2794975A1 (fr) * 1999-06-16 2000-12-22 Raouf Rekik Medicaments opthalmologiques neuro et retino-protecteurs
WO2000076499A2 (fr) * 1999-06-16 2000-12-21 Rekik, Elyes, Ben, Mohamed, Raouf Medicaments ophtalmologiques neuro-et retino-protecteurs

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3177130D1 (de) * 1980-08-30 1990-01-11 Hoechst Ag Aminosaeurederivate, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung.
DE3226768A1 (de) * 1981-11-05 1983-05-26 Hoechst Ag, 6230 Frankfurt Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
CA1341296C (en) * 1981-12-29 2001-09-25 Hansjorg Urbach 2-azabicycloalkane-3-carboxylic acid derivatives, processes for their preparation, agents containing these compounds and their use
DE3210496A1 (de) * 1982-03-23 1983-10-06 Hoechst Ag Neue derivate bicyclischer aminsaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung
DE3211397A1 (de) * 1982-03-27 1983-11-10 Hoechst Ag, 6230 Frankfurt Spiro (4.(3+n))-2-aza-3-carbonsaeure-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung
DE3211676A1 (de) * 1982-03-30 1983-10-06 Hoechst Ag Neue derivate von cycloalka (c) pyrrol-carbonsaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue cycloalka (c) pyrrol-carbonsaeuren als zwischenstufen und verfahren zu deren herstellung
US4442089A (en) * 1982-07-06 1984-04-10 E. R. Squibb & Sons, Inc. Method for treating glaucoma with topical or systemic ACE inhibitor compositions
DE3227055A1 (de) * 1982-07-20 1984-01-26 Hoechst Ag, 6230 Frankfurt Neue derivate der 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure als zwischenstufe und verfahren zu deren herstellung
ATE55911T1 (de) * 1982-12-27 1990-09-15 Schering Corp Pharmazeutische zusammensetzung.

Also Published As

Publication number Publication date
AU4028885A (en) 1985-09-26
PT80152B (de) 1987-04-07
AU578079B2 (en) 1988-10-13
DK131585D0 (da) 1985-03-22
JPS60209527A (ja) 1985-10-22
ES541436A0 (es) 1985-12-16
PT80152A (de) 1985-04-01
DE3410732A1 (de) 1985-09-26
GR850718B (es) 1985-07-19
ZA852156B (en) 1985-11-27
DK131585A (da) 1985-09-24
EP0158157A1 (de) 1985-10-16

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