ES8602708A1 - Method for the preparation of an isoxazole derivative - Google Patents

Method for the preparation of an isoxazole derivative

Info

Publication number
ES8602708A1
ES8602708A1 ES541101A ES541101A ES8602708A1 ES 8602708 A1 ES8602708 A1 ES 8602708A1 ES 541101 A ES541101 A ES 541101A ES 541101 A ES541101 A ES 541101A ES 8602708 A1 ES8602708 A1 ES 8602708A1
Authority
ES
Spain
Prior art keywords
formula
image
preparation
compound
isoxazole derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES541101A
Other languages
Spanish (es)
Other versions
ES541101A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Pharmaceutical Works PLC
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Biogal Gyogyszergyar Rt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT, Biogal Gyogyszergyar Rt filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of ES8602708A1 publication Critical patent/ES8602708A1/en
Publication of ES541101A0 publication Critical patent/ES541101A0/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

The isoxazole derivative of formula (I> < IMAGE > may be prepared by treating a compound of formula (II> < IMAGE > wherein R<1> stands for an alkyl group containing 1 to 6 carbon atoms, with an oxidizing agent, such as manganese dioxide, potassium iodide and halogen or a hypohalic acid, hydrolizing the resulting compound of formula (II> < IMAGE > wherein R stands for a hydrogen atom or an alkyl group containing 1 to 6 carbon atoms, and recovering the product obtained in a manner known per se. Compound (I) is an intermediate for the preparation of thienamycin.
ES541101A 1984-03-09 1985-03-08 PROCEDURE FOR PREPARING AN ISOXAZOL DERIVATIVE Granted ES541101A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU93984A HU191592B (en) 1984-03-09 1984-03-09 Process for preparing isoxazole-derivatives

Publications (2)

Publication Number Publication Date
ES8602708A1 true ES8602708A1 (en) 1985-12-01
ES541101A0 ES541101A0 (en) 1985-12-01

Family

ID=10952126

Family Applications (1)

Application Number Title Priority Date Filing Date
ES541101A Granted ES541101A0 (en) 1984-03-09 1985-03-08 PROCEDURE FOR PREPARING AN ISOXAZOL DERIVATIVE

Country Status (7)

Country Link
JP (1) JPS60204772A (en)
BE (1) BE901899A (en)
ES (1) ES541101A0 (en)
FR (1) FR2560875B1 (en)
GB (1) GB2155471B (en)
HU (1) HU191592B (en)
PT (1) PT80071B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT56835A (en) * 1990-03-21 1991-10-28 Basf Ag Process for the production of izoxazole-4,5-dicarbonic acid -diesthers

Also Published As

Publication number Publication date
GB2155471A (en) 1985-09-25
GB8505893D0 (en) 1985-04-11
HUT37927A (en) 1986-03-28
BE901899A (en) 1985-09-09
JPS60204772A (en) 1985-10-16
HU191592B (en) 1987-03-30
FR2560875A1 (en) 1985-09-13
FR2560875B1 (en) 1988-02-12
ES541101A0 (en) 1985-12-01
PT80071A (en) 1985-04-01
PT80071B (en) 1986-11-24
GB2155471B (en) 1987-10-21

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