ES8600771A1 - Una sonda de acido nucleico marcado. - Google Patents

Una sonda de acido nucleico marcado.

Info

Publication number
ES8600771A1
ES8600771A1 ES534156A ES534156A ES8600771A1 ES 8600771 A1 ES8600771 A1 ES 8600771A1 ES 534156 A ES534156 A ES 534156A ES 534156 A ES534156 A ES 534156A ES 8600771 A1 ES8600771 A1 ES 8600771A1
Authority
ES
Spain
Prior art keywords
nucleic acid
adducts
preparation
acid probes
acid component
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES534156A
Other languages
English (en)
Other versions
ES534156A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Molecular Diagnostics Inc
Original Assignee
Molecular Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Molecular Diagnostics Inc filed Critical Molecular Diagnostics Inc
Publication of ES534156A0 publication Critical patent/ES534156A0/es
Publication of ES8600771A1 publication Critical patent/ES8600771A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

METODO PARA LA PRODUCCION DE SONDAS DE ACIDO NUCLEICO MARCADO.COMPRENDE LA REACCION PARA FORMAR UN COMPLEJO DE UN ACIDO NUCLEICO QUE SE ENCUENTRA EN FORMA MONOCATENARIA CASI POR COMPLETO Y CONSTITUIDO POR UN COMPUESTO INTERCALADOR COLORANTE; Y SOMETER EL COMPLEJO A IRRADIACION FOTOQUIMICA PARA EFECTUAR LA REACCION COVALENTE. EL COMPONENTE DE UNION TIENE UN MARCADOR, QUE ES UN LIGANDO ESPECIFICAMENTE COMBINABLE, O EL MARCADOR SE UNE AL COMPONENTE DE UNION DESPUES DE LA REACCION FOTOQUIMICA.ESTAS SONDAS TIENEN APLICACIONES EN LA DETECCION EN ENSAYOS DE HIBRIDACION PARA LA DETERMINACION DE SECUENCIAS ESPECIFICAS DE POLINUCLEOTIDOS.
ES534156A 1983-07-14 1984-07-10 Una sonda de acido nucleico marcado. Expired ES8600771A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51393283A 1983-07-14 1983-07-14
US06/611,668 US4737454A (en) 1983-07-14 1984-05-18 Fast photochemical method of labelling nucleic acids for detection purposes in hybridization assays

Publications (2)

Publication Number Publication Date
ES534156A0 ES534156A0 (es) 1985-10-16
ES8600771A1 true ES8600771A1 (es) 1985-10-16

Family

ID=27058044

Family Applications (1)

Application Number Title Priority Date Filing Date
ES534156A Expired ES8600771A1 (es) 1983-07-14 1984-07-10 Una sonda de acido nucleico marcado.

Country Status (8)

Country Link
US (1) US4737454A (es)
EP (1) EP0131830B1 (es)
AU (1) AU567952B2 (es)
DE (1) DE3461651D1 (es)
DK (1) DK162124C (es)
ES (1) ES8600771A1 (es)
IL (1) IL72374A (es)
NZ (1) NZ208863A (es)

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US4959309A (en) * 1983-07-14 1990-09-25 Molecular Diagnostics, Inc. Fast photochemical method of labelling nucleic acids for detection purposes in hybridization assays
US4777129A (en) * 1983-12-12 1988-10-11 Molecular Diagnostics, Inc. Nucleic acid probe detectable by specific nucleic acid binding protein
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WO1985003356A1 (en) * 1984-01-27 1985-08-01 Molecular Biosystems, Inc. Assay for immobilized reporter groups
US4748111A (en) * 1984-03-12 1988-05-31 Molecular Diagnostics, Inc. Nucleic acid-protein conjugate used in immunoassay
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AU579631B2 (en) * 1984-04-05 1988-12-01 Howard Florey Institute Of Experimental Physiology And Medicine Probes: synthetic, labelled oligonucleotide strands.
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DE3431536A1 (de) * 1984-08-28 1986-03-13 Boehringer Mannheim Gmbh, 6800 Mannheim Derivatisierte nucleinsaeure-sequenz, verfahren zu deren herstellung sowie deren verwendung zum nachweis von nucleinsaeuren
US5026840A (en) * 1985-01-10 1991-06-25 Molecular Diagnostics, Inc. Photochemical nucleic acid-labeling reagent having a polyalklamine spacer
EP0187332B1 (en) * 1985-01-10 1989-02-01 Molecular Diagnostics, Inc. Photochemical method of labelling nucleic acids for detection in hybridization assays
CA1272443A (en) * 1985-02-22 1990-08-07 Nanibhushan Dattagupta Solution-phase dual hybridization assay for detecting polynucleotide sequences
ATE40409T1 (de) * 1985-08-20 1989-02-15 Apothekernes Lab Photoimmunologisches testverfahren fuer dns und rns.
US4822731A (en) * 1986-01-09 1989-04-18 Cetus Corporation Process for labeling single-stranded nucleic acids and hybridizaiton probes
US4855225A (en) * 1986-02-07 1989-08-08 Applied Biosystems, Inc. Method of detecting electrophoretically separated oligonucleotides
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US5714380A (en) 1986-10-23 1998-02-03 Amoco Corporation Closed vessel for isolating target molecules and for performing amplification
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FR2627590A1 (fr) * 1988-02-24 1989-08-25 Ire Celltarg Sa Sonde d'acides nucleiques comportant un nucleotide terminal modifie chimiquement en 5(prime) (oh) en vue de son marquage non radioactif et procedes de preparation
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US5830644A (en) * 1992-05-13 1998-11-03 Geron Corporation Method for screening for agents which increase telomerase activity in a cell
US5489508A (en) 1992-05-13 1996-02-06 University Of Texas System Board Of Regents Therapy and diagnosis of conditions related to telomere length and/or telomerase activity
US5686306A (en) * 1992-05-13 1997-11-11 Board Of Regents, The University Of Texas System Methods and reagents for lengthening telomeres
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Also Published As

Publication number Publication date
AU3048384A (en) 1985-01-17
DK342784D0 (da) 1984-07-12
EP0131830A1 (en) 1985-01-23
DK162124B (da) 1991-09-16
NZ208863A (en) 1988-06-30
DE3461651D1 (en) 1987-01-22
US4737454A (en) 1988-04-12
ES534156A0 (es) 1985-10-16
DK162124C (da) 1992-02-17
AU567952B2 (en) 1987-12-10
EP0131830B1 (en) 1986-12-10
IL72374A (en) 1989-03-31
DK342784A (da) 1985-01-15
IL72374A0 (en) 1984-11-30

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FD1A Patent lapsed

Effective date: 20050614