ES8600745A1 - Di:hydro-pyridine di:carboxylic acid ester prepn. - Google Patents
Di:hydro-pyridine di:carboxylic acid ester prepn.Info
- Publication number
- ES8600745A1 ES8600745A1 ES537914A ES537914A ES8600745A1 ES 8600745 A1 ES8600745 A1 ES 8600745A1 ES 537914 A ES537914 A ES 537914A ES 537914 A ES537914 A ES 537914A ES 8600745 A1 ES8600745 A1 ES 8600745A1
- Authority
- ES
- Spain
- Prior art keywords
- pyridine
- hydro
- carboxylic acid
- acid ester
- prepn
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
Abstract
The dimethyl ester of 2,6-dimethyl 4-(2'-nitrophenyl) 1,4-dihydropyridine 3,5-dicarboxylic acid is made by reaction of 1 mole 2-nitrobenzaldehyde diacetate with 2 moles methyl acetoacetate. Reaction is in an inert organic solvent in presence of pyridine and aq. ammonia or hexamethylene tetramine in an autoclave at 110 deg. C for 25 h. The solvent is removed in a rotary evaporator and the residue purified by crystallisation from ethanol.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES537914A ES8600745A1 (en) | 1984-11-23 | 1984-11-23 | Di:hydro-pyridine di:carboxylic acid ester prepn. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES537914A ES8600745A1 (en) | 1984-11-23 | 1984-11-23 | Di:hydro-pyridine di:carboxylic acid ester prepn. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES537914A0 ES537914A0 (en) | 1985-11-01 |
ES8600745A1 true ES8600745A1 (en) | 1985-11-01 |
Family
ID=8488190
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES537914A Expired ES8600745A1 (en) | 1984-11-23 | 1984-11-23 | Di:hydro-pyridine di:carboxylic acid ester prepn. |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES8600745A1 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2628421A1 (en) * | 1988-03-08 | 1989-09-15 | Egyt Gyogyszervegyeszeti Gyar | PROCESS FOR THE PREPARATION OF 1,4-DIHYDROPYRIDINE DERIVATIVES AND NOVEL INTERMEDIATES USEFUL FOR THIS PREPARATION |
WO1999000369A1 (en) * | 1997-06-27 | 1999-01-07 | Bayer Aktiengesellschaft | Process for preparing nifedipine |
-
1984
- 1984-11-23 ES ES537914A patent/ES8600745A1/en not_active Expired
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2628421A1 (en) * | 1988-03-08 | 1989-09-15 | Egyt Gyogyszervegyeszeti Gyar | PROCESS FOR THE PREPARATION OF 1,4-DIHYDROPYRIDINE DERIVATIVES AND NOVEL INTERMEDIATES USEFUL FOR THIS PREPARATION |
GR890100133A (en) * | 1988-03-08 | 1990-01-19 | Egyt Gyogyszervegyeszeti Gyar | 1,4-dihydropyridine derivatives preparation method |
GB2243608A (en) * | 1988-03-08 | 1991-11-06 | Egyt Gyogyszervegyeszeti Gyar | Process for the preparation of nifedipine |
BE1003199A5 (en) * | 1988-03-08 | 1992-01-14 | Egyt Gyogyszervegyeszeti Gyar | PROCESS FOR THE PREPARATION OF 1,4-DIHYDROPYRIDINE DERIVATIVES AND TO NEW INTERMEDIATES USEFUL FOR THIS PREPARATION. |
GB2243608B (en) * | 1988-03-08 | 1992-02-12 | Egyt Gyogyszervegyeszeti Gyar | Process for the preparation of 1,4-dihydro-pyridine derivatives |
WO1999000369A1 (en) * | 1997-06-27 | 1999-01-07 | Bayer Aktiengesellschaft | Process for preparing nifedipine |
Also Published As
Publication number | Publication date |
---|---|
ES537914A0 (en) | 1985-11-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE134374T1 (en) | METHOD FOR PRODUCING CONDENSED PYRIDINE COMPOUNDS | |
UA8018A1 (en) | Process for the preparation of 1-cyclopropyl-7-chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid | |
ES8600745A1 (en) | Di:hydro-pyridine di:carboxylic acid ester prepn. | |
EP0253891A4 (en) | Aromatic bismaleimido compounds and process for their preparation. | |
IE872668L (en) | 5-pyrazolyl-phenoxy acetic acids. | |
JPS54160371A (en) | Novel piperidine derivative and hypotensive agents comprising it | |
FI873327A (en) | NYA 3-ARYL-3-CYCLOALKYL-PIPERIDINE -2,6-DIONDERIVAT. | |
JPS57175166A (en) | Carbamoyloxyalkyl-1,4-dihydropyridine derivative and its preparation | |
DK0897924T3 (en) | Process for the preparation of tetrahydroindolizines | |
KR860004004A (en) | Method for preparing 4-acyloxy-3-oxo-butyric acid ester | |
DK0662475T3 (en) | Process for the preparation of 2-perfluoroalkyl-3-oxazolin-5-one. | |
IE38945L (en) | 2-amino-3,4-dihydropyridines. | |
ES8306364A1 (en) | Process for preparing a 1,4-dihydropyridine derivative | |
ES8507115A1 (en) | Di:hydro-pyridine deriv. | |
CA2089652A1 (en) | Preparation of acylaminomethanephosphonic acids and acylaminomethanephosphinic acids | |
AU586070B2 (en) | Improved process for the preparation of dihydro-1H-pyrrolizine-3,5-(2H,6H)-dione | |
JPS5520719A (en) | Preparation of 1,4-dihydropyridine derivative | |
JPS5520720A (en) | Preparation of 1,4-dihydropyridine derivative | |
ES2005543A6 (en) | Benzofuryl di:methyl di:hydro-pyridine di:ester prepn. | |
EP0357792A4 (en) | Process for preparing pyridine-2,3-dicarboxylic acid compounds | |
ES8705879A1 (en) | Benzofuryl di:methyl di:hydro-pyridine di:ester prepn. | |
ES8606277A1 (en) | Di:methyl methoxycarbonyl nitro-phenyl di:hydro-pyridine carboxylate | |
IT1204352B (en) | Methylnifenazine prepn. | |
ES8505953A1 (en) | Substd. pyridine carboxylate ester | |
ES8600237A1 (en) | Di:hydro-pyridine deriv. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19970519 |