ES8705879A1 - Benzofuryl di:methyl di:hydro-pyridine di:ester prepn. - Google Patents

Benzofuryl di:methyl di:hydro-pyridine di:ester prepn.

Info

Publication number
ES8705879A1
ES8705879A1 ES553403A ES553403A ES8705879A1 ES 8705879 A1 ES8705879 A1 ES 8705879A1 ES 553403 A ES553403 A ES 553403A ES 553403 A ES553403 A ES 553403A ES 8705879 A1 ES8705879 A1 ES 8705879A1
Authority
ES
Spain
Prior art keywords
benzofuryl
pyridine
hydro
methyl
solvent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES553403A
Other languages
Spanish (es)
Other versions
ES553403A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Menarini SA
Original Assignee
Laboratorios Menarini SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Menarini SA filed Critical Laboratorios Menarini SA
Priority to ES553403A priority Critical patent/ES8705879A1/en
Publication of ES8705879A1 publication Critical patent/ES8705879A1/en
Publication of ES553403A0 publication Critical patent/ES553403A0/en
Expired legal-status Critical Current

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  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

4-(7'-Benzofuryl)2,6-dimethyl 1,4-dihydro-pyridine 3,5-dicarboxylic acid esters of formula (I), for pharmaceutical use as hypotensive agents, are made by (a) reacting one equiv. of 7'-benzofuryl chloromethyl acetate of R1 with an equimolar amount of the beta-amino crotonate of R2 in non-alcoholic medium under reflux for 12-24 hours; (b) removing the solvent by rotary evapn.; and (c) re-crystallising from diethyl ether or solvent of similar polarity.
ES553403A 1986-03-25 1986-03-25 Benzofuryl di:methyl di:hydro-pyridine di:ester prepn. Expired ES8705879A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES553403A ES8705879A1 (en) 1986-03-25 1986-03-25 Benzofuryl di:methyl di:hydro-pyridine di:ester prepn.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES553403A ES8705879A1 (en) 1986-03-25 1986-03-25 Benzofuryl di:methyl di:hydro-pyridine di:ester prepn.

Publications (2)

Publication Number Publication Date
ES8705879A1 true ES8705879A1 (en) 1987-05-16
ES553403A0 ES553403A0 (en) 1987-05-16

Family

ID=8491057

Family Applications (1)

Application Number Title Priority Date Filing Date
ES553403A Expired ES8705879A1 (en) 1986-03-25 1986-03-25 Benzofuryl di:methyl di:hydro-pyridine di:ester prepn.

Country Status (1)

Country Link
ES (1) ES8705879A1 (en)

Also Published As

Publication number Publication date
ES553403A0 (en) 1987-05-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20070328