ES8600285A1 - Un procedimiento para la preparacion de nuevas benzamidas - Google Patents

Un procedimiento para la preparacion de nuevas benzamidas

Info

Publication number
ES8600285A1
ES8600285A1 ES537467A ES537467A ES8600285A1 ES 8600285 A1 ES8600285 A1 ES 8600285A1 ES 537467 A ES537467 A ES 537467A ES 537467 A ES537467 A ES 537467A ES 8600285 A1 ES8600285 A1 ES 8600285A1
Authority
ES
Spain
Prior art keywords
nonylbenzamide
azabicyclo
derivatives
processes
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES537467A
Other languages
English (en)
Other versions
ES537467A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES8600285A1 publication Critical patent/ES8600285A1/es
Publication of ES537467A0 publication Critical patent/ES537467A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE NUEVAS BENZAMIDAS.CONSISTE EN SOMETER A UNA REACCION DE DEGRADACION DE HOFFMAN UNCOMPUESTO DE FORMULA (II) CON UN HIPOHALITO METALICO COMO HIPOCLORITO SODICO, PARA OBTENER UN COMPUESTO DE FORMULA (I), SUS SALES O SOLVATOS FARMACEUTICAMENTE ACEPTABLES. SIENDO, R1, METILO, CL O F; R3 P-METILBENCILO Y P-FLUORBENCILO; X METOXI O ETOXI; Y AMINO O ALCANOILAMINO DE C 1 A 6; Y Z CL O BR.SE UTILIZA PARA EL TRATAMIENTO DE LA PSICOSIS EN MAMIFEROS.
ES537467A 1981-10-01 1984-11-07 Un procedimiento para la preparacion de nuevas benzamidas Granted ES537467A0 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8129717 1981-10-01
GB8135970 1981-11-28
GB8217835 1982-06-19
GB8219721 1982-07-07

Publications (2)

Publication Number Publication Date
ES8600285A1 true ES8600285A1 (es) 1985-09-16
ES537467A0 ES537467A0 (es) 1985-09-16

Family

ID=27449276

Family Applications (6)

Application Number Title Priority Date Filing Date
ES516133A Expired ES8403122A1 (es) 1981-10-01 1982-09-30 Un procedimiento de preparacion de un compuesto.
ES522940A Expired ES8503684A1 (es) 1981-10-01 1983-06-01 Un procedimiento para la preparacion de nuevos benzamidas.
ES537358A Expired ES8603486A1 (es) 1981-10-01 1984-11-02 Un procedimiento para la preparacion de nuevas benzamidas
ES537467A Granted ES537467A0 (es) 1981-10-01 1984-11-07 Un procedimiento para la preparacion de nuevas benzamidas
ES537466A Expired ES8600284A1 (es) 1981-10-01 1984-11-07 Un procedimiento para la preparacion de nuevas benzamidas
ES546355A Expired ES8608518A1 (es) 1981-10-01 1985-08-22 Un procedimiento para la preparacion de nuevas benzamidas.

Family Applications Before (3)

Application Number Title Priority Date Filing Date
ES516133A Expired ES8403122A1 (es) 1981-10-01 1982-09-30 Un procedimiento de preparacion de un compuesto.
ES522940A Expired ES8503684A1 (es) 1981-10-01 1983-06-01 Un procedimiento para la preparacion de nuevos benzamidas.
ES537358A Expired ES8603486A1 (es) 1981-10-01 1984-11-02 Un procedimiento para la preparacion de nuevas benzamidas

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES537466A Expired ES8600284A1 (es) 1981-10-01 1984-11-07 Un procedimiento para la preparacion de nuevas benzamidas
ES546355A Expired ES8608518A1 (es) 1981-10-01 1985-08-22 Un procedimiento para la preparacion de nuevas benzamidas.

Country Status (13)

Country Link
US (2) US4472413A (es)
EP (1) EP0076592B1 (es)
AU (1) AU8889782A (es)
CA (1) CA1196641A (es)
DE (1) DE3275296D1 (es)
DK (1) DK435082A (es)
ES (6) ES8403122A1 (es)
FI (1) FI823336L (es)
GB (1) GB2111479A (es)
GR (1) GR77668B (es)
NO (1) NO823301L (es)
NZ (1) NZ202031A (es)
PT (1) PT75620B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI74707C (fi) * 1982-06-29 1988-03-10 Sandoz Ag Foerfarande foer framstaellning av terapeutiskt anvaendbara alkylenoeverbryggade piperidylestrar eller -amider av bicykliska karboxylsyror.
US4778931A (en) * 1982-12-01 1988-10-18 Usv Pharmaceutical Corporation Certain [3-(1-hydroxy hexyl-tetrahydro)naphthalenes], the corresponding naphthalenes having anti-inflammatory and anti-allergic activity
FR2548666A1 (fr) * 1983-07-08 1985-01-11 Delalande Sa Nouveaux derives du nor-tropane et du granatane, leur procede de preparation et leur application en therapeutique
CH664567A5 (de) * 1983-08-26 1988-03-15 Sandoz Ag Aromatische carbonsaeure- und sulfonsaeureester oder -amide.
GB8516371D0 (en) * 1985-06-28 1985-07-31 Beecham Group Plc Compounds
US5140023A (en) * 1990-04-27 1992-08-18 G. D. Searle & Co. Azatetracycle compounds
US5223613A (en) * 1990-04-27 1993-06-29 G. D. Searle & Co. Azatetracycle compounds and process of preparing same
US5516782A (en) * 1991-03-07 1996-05-14 G. D. Searle & Co. New meso-azacyclic aromatic acid amides and esters as novel serotonergic agents
US5234921A (en) * 1991-03-07 1993-08-10 G. D. Searle & Co. Meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof as pharmaceuticals
US5219850A (en) * 1991-03-07 1993-06-15 G. D. Searle & Co. Pharmaceutically useful meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof
US5227377A (en) * 1991-03-07 1993-07-13 G. D. Searle & Co. Meso-azacyclic amides of certain bicyclic carboxylic acids
US5196547A (en) * 1991-03-07 1993-03-23 G. D. Searle & Co. Meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof
AU1578692A (en) * 1991-03-07 1992-10-06 G.D. Searle & Co. New meso-azacyclic aromatic acid amides and esters as novel serotonergic agents
US5137893A (en) * 1991-03-07 1992-08-11 G. D. Searle & Co. Pharmaceutically useful meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof
US5260303A (en) * 1991-03-07 1993-11-09 G. D. Searle & Co. Imidazopyridines as serotonergic 5-HT3 antagonists
JP3235913B2 (ja) * 1993-07-30 2001-12-04 エーザイ株式会社 アミノ安息香酸誘導体
FR2738569B1 (fr) * 1995-09-12 1997-11-28 Pf Medicament Nouveaux derives naphtamide de 3 beta-amino azabicyclo octane ou nonane, leur procede de preparation, leur utilisation a titre de medicament antipsychotique

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59004A0 (en) * 1978-12-30 1980-03-31 Beecham Group Ltd Substituted benzamides their preparation and pharmaceutical compositions containing them
FR2476088A2 (fr) * 1979-01-16 1981-08-21 Delalande Sa Nouveaux derives du nor-tropane, leur procede de preparation et leur application en therapeutique
IL61642A0 (en) * 1979-12-20 1981-01-30 Beecham Group Ltd Aniline derivatives,their preparation and pharmalceutical compositions containing them
NZ197356A (en) * 1980-06-18 1984-05-31 Beecham Group Ltd Ar-alkylsulphinyl-n-(azaicycloalkyl(alkyl)) benzamides
FR2493848B2 (fr) * 1980-11-07 1986-05-16 Delalande Sa Nouveaux derives des nor-tropane et granatane, leur procede de preparation et leur application en therapeutique

Also Published As

Publication number Publication date
ES546355A0 (es) 1986-06-16
ES516133A0 (es) 1984-03-01
GB2111479A (en) 1983-07-06
ES8403122A1 (es) 1984-03-01
GR77668B (es) 1984-09-25
ES522940A0 (es) 1985-03-01
EP0076592A3 (en) 1983-08-24
DE3275296D1 (en) 1987-03-05
CA1196641A (en) 1985-11-12
ES537358A0 (es) 1985-12-16
ES537466A0 (es) 1985-09-16
NZ202031A (en) 1985-03-20
FI823336A0 (fi) 1982-09-29
AU8889782A (en) 1983-04-14
EP0076592B1 (en) 1987-01-28
DK435082A (da) 1983-04-02
US4560757A (en) 1985-12-24
PT75620A (en) 1982-10-01
NO823301L (no) 1983-04-05
ES8608518A1 (es) 1986-06-16
EP0076592A2 (en) 1983-04-13
ES8503684A1 (es) 1985-03-01
PT75620B (en) 1985-01-08
FI823336L (fi) 1983-04-02
ES8600284A1 (es) 1985-09-16
US4472413A (en) 1984-09-18
ES8603486A1 (es) 1985-12-16
ES537467A0 (es) 1985-09-16

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