ES8600284A1 - Un procedimiento para la preparacion de nuevas benzamidas - Google Patents

Un procedimiento para la preparacion de nuevas benzamidas

Info

Publication number
ES8600284A1
ES8600284A1 ES537466A ES537466A ES8600284A1 ES 8600284 A1 ES8600284 A1 ES 8600284A1 ES 537466 A ES537466 A ES 537466A ES 537466 A ES537466 A ES 537466A ES 8600284 A1 ES8600284 A1 ES 8600284A1
Authority
ES
Spain
Prior art keywords
nonylbenzamide
azabicyclo
derivatives
processes
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES537466A
Other languages
English (en)
Other versions
ES537466A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES537466A0 publication Critical patent/ES537466A0/es
Publication of ES8600284A1 publication Critical patent/ES8600284A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE NUEVAS BENZAMIDAS.CONSISTE EN REDUCIR UN COMPUESTO DE FORMULA (II) CON UN REDUCTOR SELECCIONADO ENTRE CL2SN/HCL O H2/NI-RANEY, PARA OBTENER UN COMPUESTO DE FORMULA (I) O SUS SALES O SOLVATOS FARMACEUTICAMENTE ACEPTABLES. SIENDO, R1 METILO, CL O BR; R3 P-METILBENCILO, P-CLOROBENCILO O P-FLUORBENCILO; X METOXI O ETOXI; Y AMINO OALCANOILAMINO C 1 A 6; Y Z; H, CL O BR.SE UTILIZAN EN EL TRATAMIENTO DE LOS TRASTORNOS DEL SISTEMA NERVIOSO CENTRAL (SNC).
ES537466A 1981-10-01 1984-11-07 Un procedimiento para la preparacion de nuevas benzamidas Expired ES8600284A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8129717 1981-10-01
GB8135970 1981-11-28
GB8217835 1982-06-19
GB8219721 1982-07-07

Publications (2)

Publication Number Publication Date
ES537466A0 ES537466A0 (es) 1985-09-16
ES8600284A1 true ES8600284A1 (es) 1985-09-16

Family

ID=27449276

Family Applications (6)

Application Number Title Priority Date Filing Date
ES516133A Granted ES516133A0 (es) 1981-10-01 1982-09-30 Un procedimiento de preparacion de un compuesto.
ES522940A Expired ES8503684A1 (es) 1981-10-01 1983-06-01 Un procedimiento para la preparacion de nuevos benzamidas.
ES537358A Granted ES537358A0 (es) 1981-10-01 1984-11-02 Un procedimiento para la preparacion de nuevas benzamidas
ES537466A Expired ES8600284A1 (es) 1981-10-01 1984-11-07 Un procedimiento para la preparacion de nuevas benzamidas
ES537467A Expired ES8600285A1 (es) 1981-10-01 1984-11-07 Un procedimiento para la preparacion de nuevas benzamidas
ES546355A Expired ES8608518A1 (es) 1981-10-01 1985-08-22 Un procedimiento para la preparacion de nuevas benzamidas.

Family Applications Before (3)

Application Number Title Priority Date Filing Date
ES516133A Granted ES516133A0 (es) 1981-10-01 1982-09-30 Un procedimiento de preparacion de un compuesto.
ES522940A Expired ES8503684A1 (es) 1981-10-01 1983-06-01 Un procedimiento para la preparacion de nuevos benzamidas.
ES537358A Granted ES537358A0 (es) 1981-10-01 1984-11-02 Un procedimiento para la preparacion de nuevas benzamidas

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES537467A Expired ES8600285A1 (es) 1981-10-01 1984-11-07 Un procedimiento para la preparacion de nuevas benzamidas
ES546355A Expired ES8608518A1 (es) 1981-10-01 1985-08-22 Un procedimiento para la preparacion de nuevas benzamidas.

Country Status (13)

Country Link
US (2) US4472413A (es)
EP (1) EP0076592B1 (es)
AU (1) AU8889782A (es)
CA (1) CA1196641A (es)
DE (1) DE3275296D1 (es)
DK (1) DK435082A (es)
ES (6) ES516133A0 (es)
FI (1) FI823336L (es)
GB (1) GB2111479A (es)
GR (1) GR77668B (es)
NO (1) NO823301L (es)
NZ (1) NZ202031A (es)
PT (1) PT75620B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2531083B1 (fr) * 1982-06-29 1986-11-28 Sandoz Sa Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
US4778931A (en) * 1982-12-01 1988-10-18 Usv Pharmaceutical Corporation Certain [3-(1-hydroxy hexyl-tetrahydro)naphthalenes], the corresponding naphthalenes having anti-inflammatory and anti-allergic activity
FR2548666A1 (fr) * 1983-07-08 1985-01-11 Delalande Sa Nouveaux derives du nor-tropane et du granatane, leur procede de preparation et leur application en therapeutique
DE3429830A1 (de) * 1983-08-26 1985-03-07 Sandoz-Patent-GmbH, 7850 Lörrach Automatische carbonsaeure- und sulfonsaeureester oder -amide
GB8516371D0 (en) * 1985-06-28 1985-07-31 Beecham Group Plc Compounds
US5223613A (en) * 1990-04-27 1993-06-29 G. D. Searle & Co. Azatetracycle compounds and process of preparing same
US5140023A (en) * 1990-04-27 1992-08-18 G. D. Searle & Co. Azatetracycle compounds
US5227377A (en) * 1991-03-07 1993-07-13 G. D. Searle & Co. Meso-azacyclic amides of certain bicyclic carboxylic acids
US5516782A (en) * 1991-03-07 1996-05-14 G. D. Searle & Co. New meso-azacyclic aromatic acid amides and esters as novel serotonergic agents
US5234921A (en) * 1991-03-07 1993-08-10 G. D. Searle & Co. Meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof as pharmaceuticals
US5260303A (en) * 1991-03-07 1993-11-09 G. D. Searle & Co. Imidazopyridines as serotonergic 5-HT3 antagonists
US5196547A (en) * 1991-03-07 1993-03-23 G. D. Searle & Co. Meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof
EP0528026A1 (en) * 1991-03-07 1993-02-24 G.D. Searle & Co. New meso-azacyclic aromatic acid amides and esters as novel serotonergic agents
US5219850A (en) * 1991-03-07 1993-06-15 G. D. Searle & Co. Pharmaceutically useful meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof
US5137893A (en) * 1991-03-07 1992-08-11 G. D. Searle & Co. Pharmaceutically useful meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof
JP3235913B2 (ja) * 1993-07-30 2001-12-04 エーザイ株式会社 アミノ安息香酸誘導体
FR2738569B1 (fr) * 1995-09-12 1997-11-28 Pf Medicament Nouveaux derives naphtamide de 3 beta-amino azabicyclo octane ou nonane, leur procede de preparation, leur utilisation a titre de medicament antipsychotique

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59004A0 (en) * 1978-12-30 1980-03-31 Beecham Group Ltd Substituted benzamides their preparation and pharmaceutical compositions containing them
FR2476088A2 (fr) * 1979-01-16 1981-08-21 Delalande Sa Nouveaux derives du nor-tropane, leur procede de preparation et leur application en therapeutique
IL61642A0 (en) * 1979-12-20 1981-01-30 Beecham Group Ltd Aniline derivatives,their preparation and pharmalceutical compositions containing them
NZ197356A (en) * 1980-06-18 1984-05-31 Beecham Group Ltd Ar-alkylsulphinyl-n-(azaicycloalkyl(alkyl)) benzamides
FR2493848B2 (fr) * 1980-11-07 1986-05-16 Delalande Sa Nouveaux derives des nor-tropane et granatane, leur procede de preparation et leur application en therapeutique

Also Published As

Publication number Publication date
DK435082A (da) 1983-04-02
EP0076592A2 (en) 1983-04-13
ES8403122A1 (es) 1984-03-01
ES516133A0 (es) 1984-03-01
FI823336A0 (fi) 1982-09-29
PT75620B (en) 1985-01-08
DE3275296D1 (en) 1987-03-05
NO823301L (no) 1983-04-05
ES537467A0 (es) 1985-09-16
PT75620A (en) 1982-10-01
ES8603486A1 (es) 1985-12-16
US4472413A (en) 1984-09-18
EP0076592B1 (en) 1987-01-28
AU8889782A (en) 1983-04-14
ES546355A0 (es) 1986-06-16
ES537466A0 (es) 1985-09-16
US4560757A (en) 1985-12-24
ES537358A0 (es) 1985-12-16
ES8600285A1 (es) 1985-09-16
GB2111479A (en) 1983-07-06
FI823336L (fi) 1983-04-02
ES522940A0 (es) 1985-03-01
GR77668B (es) 1984-09-25
NZ202031A (en) 1985-03-20
ES8608518A1 (es) 1986-06-16
CA1196641A (en) 1985-11-12
ES8503684A1 (es) 1985-03-01
EP0076592A3 (en) 1983-08-24

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