ES8600278A1 - Un procedimiento para la preparacion de nuevas fenoxialquil-1-2-4-triazolonas. - Google Patents
Un procedimiento para la preparacion de nuevas fenoxialquil-1-2-4-triazolonas.Info
- Publication number
- ES8600278A1 ES8600278A1 ES533753A ES533753A ES8600278A1 ES 8600278 A1 ES8600278 A1 ES 8600278A1 ES 533753 A ES533753 A ES 533753A ES 533753 A ES533753 A ES 533753A ES 8600278 A1 ES8600278 A1 ES 8600278A1
- Authority
- ES
- Spain
- Prior art keywords
- triazol
- antidepressants
- phenoxyeth
- triazolones
- piperazinyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C265/00—Derivatives of isocyanic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/20—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/067—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE NUEVAS FENOXIALQUIL-1,2,4-TRIAZOLONAS.COMPRENDE: HACER REACCIONAR UN COMPUESTO DE FORMULA (I), DONDE AK ES H O ES UN RADICAL PIPERAZINILO DE FORMULA (II), O UN RADICAL DE FORMULA (III), EN DONDE XL ES UN GRUPO SALIENTE COMO HALOGENO, SULFATO U OTROS, Y BK ES H O UN RADICAL DE FORMULA (VI) DONDE N ES 2-4, X1 ES 0 O UN ENLACE DIRECTO E Y ES H HALOGENO, ALCOXI INFERIOR DE C 1 A 4 U OTROS, CON UN GANTE ALQUILANTE DE FORMULA (V) EN DONDE R1 ES HALOGENO O ALCOXI CUANDO NO ES 2-4 Y R1 ES H CUANDO N ES 3-4, N ES UN NUMERO ENTERO DE 2 A 4 X ES HALOGENO U OTROS, O CON UN AGENTE ALQUILANTE DE FORMULA (VI) ES DONDE XK ES HALOGENO, FOSFATO U OTROS O CON UNA PIPERAZINA DE FORMULA (VII), PARA OBTENER EL COMPUESTO DE FORMULA (VIII) EN DONDE N ES 2-4, R2 ES H O ALQUILO INFERIOR, X1 ES O O UN ENLACE DIRECTO, Y ES H, HALOGENO U OTROS, Y Z ES BENCILO O UN RADICAL SELECCIONADO.SE USAN EN EL TRATAMIENTO DE LA DEPRESION.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/509,266 US4487773A (en) | 1981-03-16 | 1983-06-29 | 1,2,4-Triazol-3-one antidepressants |
Publications (2)
Publication Number | Publication Date |
---|---|
ES533753A0 ES533753A0 (es) | 1985-10-01 |
ES8600278A1 true ES8600278A1 (es) | 1985-10-01 |
Family
ID=24025922
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES533753A Expired ES8600278A1 (es) | 1983-06-29 | 1984-06-27 | Un procedimiento para la preparacion de nuevas fenoxialquil-1-2-4-triazolonas. |
Country Status (21)
Country | Link |
---|---|
US (1) | US4487773A (es) |
JP (1) | JPS6036469A (es) |
KR (1) | KR890000637B1 (es) |
AU (1) | AU579826B2 (es) |
BE (1) | BE900038A (es) |
CA (1) | CA1255310A (es) |
CH (2) | CH663412A5 (es) |
DE (1) | DE3423898A1 (es) |
DK (1) | DK316784A (es) |
ES (1) | ES8600278A1 (es) |
FI (1) | FI842597A (es) |
FR (1) | FR2551439B1 (es) |
GB (4) | GB2142631B (es) |
GR (1) | GR81450B (es) |
IT (1) | IT1176342B (es) |
LU (1) | LU85442A1 (es) |
MY (1) | MY102072A (es) |
NL (1) | NL8402028A (es) |
PT (1) | PT78816A (es) |
SE (1) | SE8403460L (es) |
ZA (1) | ZA844887B (es) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4596884A (en) * | 1983-11-30 | 1986-06-24 | Bristol-Myers Company | 4-(2-phenoxyethyl)-1,2,4-triazolone process intermediates |
YU44721B (en) * | 1983-11-30 | 1990-12-31 | Bristol Myers Co | Process for obtaining 4-(2-phenoxyethyl)-1,2,4-triazolone |
DE3934081A1 (de) * | 1989-10-12 | 1991-04-18 | Bayer Ag | Sulfonylaminocarbonyltriazolinone |
US4784998A (en) * | 1987-04-06 | 1988-11-15 | Bristol-Myers Company | 1,3,4-oxadiazole pyschotropic compounds |
EP0350145A3 (en) * | 1988-04-28 | 1990-07-04 | Yamanouchi Pharmaceutical Co. Ltd. | Pyridylthiazolidine carboxamide derivatives and their intermediates and production of both |
FR2642759B1 (fr) * | 1989-02-09 | 1991-05-17 | Laboratorios Esteve Sa | Derives de pyrimidyl-piperazinyl-alkyl azoles avec activite anxiolytique et/ou tranquillisante |
US5243051A (en) * | 1990-03-05 | 1993-09-07 | Shionigi & Co., Ltd. | Tetrahydropyridine derivatives |
US5149817A (en) * | 1990-03-05 | 1992-09-22 | Shionogi & Co., Ltd. | Teirahydropyridine derivatives |
US5266571A (en) * | 1992-01-09 | 1993-11-30 | Amer Moh Samir | Treatment of hemorrhoids with 5-HT2 antagonists |
US5256664A (en) * | 1992-04-28 | 1993-10-26 | Bristol-Myers Squibb Company | Antidepressant 3-halophenylpiperazinylpropyl derivatives of substituted triazolones and triazoldiones |
DE4425144A1 (de) * | 1994-07-15 | 1996-01-18 | Basf Ag | Triazolverbindungen und deren Verwendung |
CA2160423A1 (en) * | 1994-11-02 | 1996-05-03 | Hemant N. Joshi | Salts of nefazodone having improved dissolution rates |
US6403593B1 (en) | 1995-07-14 | 2002-06-11 | Abbott Laboratories | Triazole compounds and the use thereof |
DE19728996A1 (de) | 1997-07-07 | 1999-01-14 | Basf Ag | Triazolverbindungen und deren Verwendung |
KR20010073153A (ko) | 1998-09-18 | 2001-07-31 | 제임스 에이. 아노 | 녹내장 치료용의 세로토닌성 5ht2 작용제 |
ES2152860B1 (es) * | 1998-10-23 | 2001-08-16 | Finaf 92 Sa | Forma cristalina de la nefazodona y procedimiento para su preparacion. |
ES2188344B1 (es) * | 2000-11-29 | 2004-09-16 | Laboratorios Vita, S.A. | Compuestos derivados de benzotiofeno, su procedimiento de obtencion y utilizacion de los mismos. |
NZ539643A (en) * | 2002-10-11 | 2006-11-30 | Smithkline Beecham Corp | KSP inhibitors of formula I that can be used to treat cellular proliferative disease |
UA82875C2 (en) * | 2003-04-30 | 2008-05-26 | Insecticidal (dihalopropenyl) phenylalkyl substituted dihydrobenzofuran and dihydrobenzopyran derivatives and method for controlling insects | |
CA2567249A1 (en) * | 2004-04-19 | 2006-10-05 | Jds Pharmaceuticals, Llc | Lithium combinations, and uses related thereto |
AR049382A1 (es) * | 2004-05-18 | 2006-07-26 | Fmc Corp | Derivados de la urea ciclica substituida |
US20060073172A1 (en) * | 2004-10-01 | 2006-04-06 | Schneider L W | Stabilized ophthalmic solution for the treatment of glaucoma and lowering intraocular pressure |
WO2009019472A1 (en) | 2007-08-07 | 2009-02-12 | Prosarix Limited | 1, 2, 4 -triazole derivatives as serotonergic modulators |
EP2303897A4 (en) * | 2008-06-05 | 2012-02-22 | Harvard College | HIGH VALENCIA PALLADIUM FLUORIDE COMPLEXES AND USES THEREOF |
JP2012509351A (ja) | 2008-11-20 | 2012-04-19 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 有機化合物のフッ素化 |
WO2010081036A2 (en) * | 2009-01-09 | 2010-07-15 | President And Fellows Of Harvard College | Fluorine containing compounds and methods of use thereof |
EP2697204B1 (en) | 2011-04-12 | 2017-03-08 | President and Fellows of Harvard College | Fluorination of organic compounds |
WO2013134562A1 (en) | 2012-03-09 | 2013-09-12 | Inception 2, Inc. | Triazolone compounds and uses thereof |
US9273083B2 (en) | 2012-09-26 | 2016-03-01 | President And Fellows Of Harvard College | Nickel fluorinating complexes and uses thereof |
EP2935228B9 (en) | 2012-12-20 | 2017-12-06 | Inception 2, Inc. | Triazolone compounds and uses thereof |
WO2014175132A1 (ja) | 2013-04-26 | 2014-10-30 | 日本卓球株式会社 | 卓球ボールおよび卓球ボール用熱可塑性樹脂組成物 |
CA2921420A1 (en) | 2013-09-06 | 2015-03-12 | Inception 2, Inc. | Triazolone compounds and uses thereof |
WO2015058047A2 (en) | 2013-10-18 | 2015-04-23 | President And Fellows Of Harvard College | Fluorination of organic compounds |
WO2023218251A1 (en) * | 2022-05-10 | 2023-11-16 | Clearsynth Labs Limied | Novel deuterium-enriched nefazodone analogues and method for preparing thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1066857B (it) * | 1965-12-15 | 1985-03-12 | Acraf | Derivati della s ipiazolo 4.3 a piridina e processi per la loro preparazione |
IT1052119B (it) * | 1972-10-16 | 1981-06-20 | Sigma Tau Ind Farmaceuti | Derivati del triazolinone e procedimento per la loro preparazione |
IT1052130B (it) * | 1973-10-15 | 1981-06-20 | Sigma Tau Ind Farmaceuti | Derivati del triazolinone e procedimento per la loro preparazione |
US4338317A (en) * | 1981-03-16 | 1982-07-06 | Mead Johnson & Company | Phenoxyethyl-1,2,4,-triazol-3-one antidepressants |
US4386091A (en) * | 1982-02-24 | 1983-05-31 | Mead Johnson & Company | 2-Phenoxyalkyl-1,2,4-triazol-3-one antidepressants |
US4613600A (en) * | 1983-09-30 | 1986-09-23 | Mead Johnson & Company | Antidepressant 1,2,4-triazolone compounds |
-
1983
- 1983-06-29 US US06/509,266 patent/US4487773A/en not_active Expired - Fee Related
-
1984
- 1984-06-26 ZA ZA844887A patent/ZA844887B/xx unknown
- 1984-06-26 GR GR75111A patent/GR81450B/el unknown
- 1984-06-27 CA CA000457534A patent/CA1255310A/en not_active Expired
- 1984-06-27 NL NL8402028A patent/NL8402028A/nl not_active Application Discontinuation
- 1984-06-27 FR FR848410136A patent/FR2551439B1/fr not_active Expired
- 1984-06-27 AU AU29953/84A patent/AU579826B2/en not_active Ceased
- 1984-06-27 FI FI842597A patent/FI842597A/fi not_active Application Discontinuation
- 1984-06-27 ES ES533753A patent/ES8600278A1/es not_active Expired
- 1984-06-28 KR KR1019840003692A patent/KR890000637B1/ko not_active IP Right Cessation
- 1984-06-28 CH CH1910/87A patent/CH663412A5/de not_active IP Right Cessation
- 1984-06-28 CH CH3130/84A patent/CH662562A5/de not_active IP Right Cessation
- 1984-06-28 DK DK316784A patent/DK316784A/da not_active Application Discontinuation
- 1984-06-28 DE DE19843423898 patent/DE3423898A1/de not_active Ceased
- 1984-06-28 LU LU85442A patent/LU85442A1/fr unknown
- 1984-06-28 BE BE0/213240A patent/BE900038A/fr not_active IP Right Cessation
- 1984-06-28 PT PT78816A patent/PT78816A/pt not_active IP Right Cessation
- 1984-06-28 IT IT21641/84A patent/IT1176342B/it active
- 1984-06-28 GB GB08416435A patent/GB2142631B/en not_active Expired
- 1984-06-28 SE SE8403460A patent/SE8403460L/xx not_active Application Discontinuation
- 1984-06-29 JP JP59133401A patent/JPS6036469A/ja active Granted
-
1987
- 1987-02-17 GB GB08703634A patent/GB2185021B/en not_active Expired
- 1987-02-17 GB GB08703632A patent/GB2184446A/en not_active Withdrawn
- 1987-02-17 GB GB08703633A patent/GB2184447B/en not_active Expired
- 1987-09-29 MY MYPI87002184A patent/MY102072A/en unknown
Also Published As
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