ES8507464A1 - Procedimiento de obtencion de -(((2-hidroxi-1, 1-dimetil-etil)-amino)metil), benceno-metanol clorhidrato - Google Patents

Procedimiento de obtencion de -(((2-hidroxi-1, 1-dimetil-etil)-amino)metil), benceno-metanol clorhidrato

Info

Publication number
ES8507464A1
ES8507464A1 ES537634A ES537634A ES8507464A1 ES 8507464 A1 ES8507464 A1 ES 8507464A1 ES 537634 A ES537634 A ES 537634A ES 537634 A ES537634 A ES 537634A ES 8507464 A1 ES8507464 A1 ES 8507464A1
Authority
ES
Spain
Prior art keywords
hydroxy
benzenemethanol
methy
antiinflammatory
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES537634A
Other languages
English (en)
Other versions
ES537634A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Especialidades Latinas Medicamentos Universales SA
Original Assignee
Especialidades Latinas Medicamentos Universales SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Especialidades Latinas Medicamentos Universales SA filed Critical Especialidades Latinas Medicamentos Universales SA
Priority to ES537634A priority Critical patent/ES8507464A1/es
Publication of ES537634A0 publication Critical patent/ES537634A0/es
Publication of ES8507464A1 publication Critical patent/ES8507464A1/es
Priority to MX9026A priority patent/MX163198B/es
Priority to CH4785/85A priority patent/CH670823A5/fr
Priority to JP60249089A priority patent/JPS61143344A/ja
Priority to PT81479A priority patent/PT81479B/pt
Priority to IT48792/85A priority patent/IT1184670B/it
Priority to FR858516852A priority patent/FR2573071B1/fr
Priority to BE0/215872A priority patent/BE903651A/fr
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/30—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters

Abstract

PROCEDIMIENTO DE OBTENCION DE BAB-Y(2-HIDROXI-1,1-DIMETIL-ETIL)-AMINOZ,BENCENO-METANOL CLORHIDRATO.COMPRENDE: A) HACER REACCIONAR EL ACIDO BAB-OXO-FENIL ACETICO CON CLORURO DE TIONILO, EN SOLUCION BENCENICA ANHIDRA, PARA OBYENER EL CLORURO DE ACIDO CORRESPONDIENTE; B) HACER REACCIONAR EL CLORURO DEL BAB-OXO-FENIL-ACETIL CON 2-AMINO-2-METIL-1-PROPANOL, PARA OBTENER LA AMIDA TERC-BUTANOL-N-BAB-OXO-FENOL-ACETAMIDA DE FORMULA (II); Y C) REDUCIR AL COMPUESTO DE FORMULA (II) CON LI HH4, PARA OBTENER UN COMPUESTO DE FORMULA (I).
ES537634A 1984-11-14 1984-11-14 Procedimiento de obtencion de -(((2-hidroxi-1, 1-dimetil-etil)-amino)metil), benceno-metanol clorhidrato Expired ES8507464A1 (es)

Priority Applications (8)

Application Number Priority Date Filing Date Title
ES537634A ES8507464A1 (es) 1984-11-14 1984-11-14 Procedimiento de obtencion de -(((2-hidroxi-1, 1-dimetil-etil)-amino)metil), benceno-metanol clorhidrato
MX9026A MX163198B (es) 1984-11-14 1985-11-07 Procedimiento de obtencion de alfa-(((2-hidroxi-1,1-dimetil-etil)amino)metil),benceno metanol clorhidrato
CH4785/85A CH670823A5 (es) 1984-11-14 1985-11-07
JP60249089A JPS61143344A (ja) 1984-11-14 1985-11-08 α−〔〔（２−ヒドロキシ−１，１−ジメチル−エチル）アミン〕メチル〕，ベンゼンメタノ−ル、その製造方法およびそれを含有する抗炎症剤
PT81479A PT81479B (pt) 1984-11-14 1985-11-12 Processo para a preparacao de cloridrato de alfa-<(2-hidroxi-1,1-dimetil-etil)-amino>-benzeno-metanol
IT48792/85A IT1184670B (it) 1984-11-14 1985-11-14 Alfa-((2-idrossi-1,1-dimetil-etil)ammino)metil)-benzol-metanolo e relativi sali,aventi attivita' antiinfiammatoria,procedimento per la loro preparazione e composizioni farmacceutiche che li contengono
FR858516852A FR2573071B1 (fr) 1984-11-14 1985-11-14 N-(hydroxy-2-dimethyl-1,1-ethyl)-amino-2-phenyl-1-ethanol utile notamment comme anti-inflammatoire, et son procede de preparation
BE0/215872A BE903651A (fr) 1984-11-14 1985-11-14 Alpha - (((2 - hydroxy -1,1- dimethyl - ethyl) amino) methyl), benzene methanol et ses sels, leurs procedes de preparation et leur utilisation.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES537634A ES8507464A1 (es) 1984-11-14 1984-11-14 Procedimiento de obtencion de -(((2-hidroxi-1, 1-dimetil-etil)-amino)metil), benceno-metanol clorhidrato

Publications (2)

Publication Number Publication Date
ES537634A0 ES537634A0 (es) 1985-09-16
ES8507464A1 true ES8507464A1 (es) 1985-09-16

Family

ID=8488129

Family Applications (1)

Application Number Title Priority Date Filing Date
ES537634A Expired ES8507464A1 (es) 1984-11-14 1984-11-14 Procedimiento de obtencion de -(((2-hidroxi-1, 1-dimetil-etil)-amino)metil), benceno-metanol clorhidrato

Country Status (8)

Country Link
JP (1) JPS61143344A (es)
BE (1) BE903651A (es)
CH (1) CH670823A5 (es)
ES (1) ES8507464A1 (es)
FR (1) FR2573071B1 (es)
IT (1) IT1184670B (es)
MX (1) MX163198B (es)
PT (1) PT81479B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2862537B1 (fr) * 2003-11-21 2006-03-03 Galderma Res & Dev Utilisation du fepradinol pour la preparation d'une composition pharmaceutique pour le traitement de la rosacee

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1618005A1 (de) * 1966-09-22 1971-09-09 Thomae Gmbh Dr K Verfahren zur Herstellung von neuen Amino-dihalogen-phenyl-aethylaminen

Also Published As

Publication number Publication date
FR2573071B1 (fr) 1989-03-10
ES537634A0 (es) 1985-09-16
IT1184670B (it) 1987-10-28
CH670823A5 (es) 1989-07-14
BE903651A (fr) 1986-03-03
FR2573071A1 (fr) 1986-05-16
PT81479A (en) 1985-12-01
JPS61143344A (ja) 1986-07-01
PT81479B (pt) 1987-11-11
MX163198B (es) 1992-01-30
IT8548792A0 (it) 1985-11-14

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