ES8506597A1 - Un procedimiento para preparar un peptido de resina. - Google Patents

Un procedimiento para preparar un peptido de resina.

Info

Publication number
ES8506597A1
ES8506597A1 ES532050A ES532050A ES8506597A1 ES 8506597 A1 ES8506597 A1 ES 8506597A1 ES 532050 A ES532050 A ES 532050A ES 532050 A ES532050 A ES 532050A ES 8506597 A1 ES8506597 A1 ES 8506597A1
Authority
ES
Spain
Prior art keywords
peptides
calcitonin
asparagine
des
disclosed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES532050A
Other languages
English (en)
Other versions
ES532050A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Armour Pharmaceutical Co
Original Assignee
Armour Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Armour Pharmaceutical Co filed Critical Armour Pharmaceutical Co
Publication of ES532050A0 publication Critical patent/ES532050A0/es
Publication of ES8506597A1 publication Critical patent/ES8506597A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/585Calcitonins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE UN COMPUESTO DE FORMULA (I), EN LA QUE R ES UNA PORCION DE RESINA DE POLIESTIRENO; T ES UN GRUPO NITRO O TOSILO; Y R1, R2, X2, BZ, V Y W PUEDEN SER VARIOS TIPOS DE RADICALES.COMPRENDE LA UNION DE UN AMINOACIDO PRO CON UNA RESINA DE BENZHIDRIALAMINA DE FORMULA (II); ELIMINACION DEL GRUPO PROTECTOR DE LA POSICION BAB-AMINO DEL PRO; SELECCION DE CADA AMINOACIDO EN LA SECUENCIA INDICADA EN LA FORMULA (I); DOTACION DEL GRUPO PROTECTOR EN LA POSICION BAB-AMINO AL AMINO-ACIDO SELECCIONADO; UNION DE ESTE AMINOACIDO CON EL AMINOACIDO UNIDO AL PEPTIDO DE RESINA; Y ELIMINACION DEL GRUPO PROTECTOR EN LA POSICION BAB-AMINO.ESTOS PEPTIDOS TIENEN APLICACIONES PARA LA PRODUCCION DE CALCITONINAS ACTIVAS.
ES532050A 1982-02-12 1984-04-30 Un procedimiento para preparar un peptido de resina. Expired ES8506597A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/348,473 US4391747A (en) 1982-02-12 1982-02-12 Des asparagine-3-calcitonin

Publications (2)

Publication Number Publication Date
ES532050A0 ES532050A0 (es) 1985-08-01
ES8506597A1 true ES8506597A1 (es) 1985-08-01

Family

ID=23368204

Family Applications (2)

Application Number Title Priority Date Filing Date
ES519734A Expired ES8500217A1 (es) 1982-02-12 1983-02-11 Un procedimiento para preparar peptidos sinteticos del tipo de las calcitoninas.
ES532050A Expired ES8506597A1 (es) 1982-02-12 1984-04-30 Un procedimiento para preparar un peptido de resina.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES519734A Expired ES8500217A1 (es) 1982-02-12 1983-02-11 Un procedimiento para preparar peptidos sinteticos del tipo de las calcitoninas.

Country Status (5)

Country Link
US (1) US4391747A (es)
ES (2) ES8500217A1 (es)
FR (1) FR2521554B1 (es)
GB (1) GB2116563B (es)
IT (1) IT1163095B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4663309A (en) * 1983-06-29 1987-05-05 University Patents, Inc. Novel peptide hormones with calcitonin-like activity
DE3640042A1 (de) * 1985-12-04 1987-06-11 Sandoz Ag Neue calcitoninderivate
US4820804A (en) * 1987-04-21 1989-04-11 Rorer Pharmaceutical Corporation Analogs of [1,7-di-alanine, des-19-leucine]calcitonin
US4824936A (en) * 1987-05-06 1989-04-25 Rorer Pharmaceutical Corporation (19-Alanine) calcitonin

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5716977B2 (es) * 1972-12-07 1982-04-08
US3926938A (en) * 1974-08-12 1975-12-16 Armour Pharma Synthesis of salmon calcitonin
US3929758A (en) * 1974-09-12 1975-12-30 Armour Pharma Cyclization of cysteine-containing peptides
US4217268A (en) * 1978-07-20 1980-08-12 Hughes John L Synthesis of peptides

Also Published As

Publication number Publication date
ES532050A0 (es) 1985-08-01
IT1163095B (it) 1987-04-08
GB8303368D0 (en) 1983-03-16
ES519734A0 (es) 1984-10-01
FR2521554A1 (fr) 1983-08-19
GB2116563A (en) 1983-09-28
US4391747A (en) 1983-07-05
ES8500217A1 (es) 1984-10-01
IT8319550A0 (it) 1983-02-11
GB2116563B (en) 1985-03-27
FR2521554B1 (fr) 1986-08-22

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