ES8506445A1 - Preparation of aerosol compositions - Google Patents

Preparation of aerosol compositions

Info

Publication number
ES8506445A1
ES8506445A1 ES535163A ES535163A ES8506445A1 ES 8506445 A1 ES8506445 A1 ES 8506445A1 ES 535163 A ES535163 A ES 535163A ES 535163 A ES535163 A ES 535163A ES 8506445 A1 ES8506445 A1 ES 8506445A1
Authority
ES
Spain
Prior art keywords
component
preparation
components
under pressure
chamber
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES535163A
Other languages
Spanish (es)
Other versions
ES535163A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sterwin AG
Original Assignee
Sterwin AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterwin AG filed Critical Sterwin AG
Publication of ES535163A0 publication Critical patent/ES535163A0/en
Publication of ES8506445A1 publication Critical patent/ES8506445A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to the preparation of aerosol compositions. The invention provides a method for the preparation of liposomes in which at least two separate components are brought together under pressure, a first component comprising water and a second component comprising a lipid material. The components are then passed as a mixture under pressure through a nozzle or other arrangement to produce an aerosol spray containing liposomes. In addition, at least one of the first or second components preferably includes a separate active material. The invention also provides a pack for use in preparing a liposomal aerosol comprising at least a first and a second chamber, one chamber containing a first component comprising water and the other chamber containing a second component comprising a lipid material, and one or both of the chambers and/or a third chamber including a propellant material. The pack also includes an arrangement for dispensing as a spray a mixture of the first and second components fed from their respective chambers under pressure developed by the propellant material or materials.
ES535163A 1983-08-17 1984-08-14 Preparation of aerosol compositions Expired ES8506445A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838322178A GB8322178D0 (en) 1983-08-17 1983-08-17 Preparing aerosol compositions

Publications (2)

Publication Number Publication Date
ES535163A0 ES535163A0 (en) 1985-08-01
ES8506445A1 true ES8506445A1 (en) 1985-08-01

Family

ID=10547457

Family Applications (1)

Application Number Title Priority Date Filing Date
ES535163A Expired ES8506445A1 (en) 1983-08-17 1984-08-14 Preparation of aerosol compositions

Country Status (22)

Country Link
JP (1) JPS6089414A (en)
KR (1) KR850001689A (en)
AT (1) AT389993B (en)
AU (1) AU569314B2 (en)
BE (1) BE900375A (en)
CH (1) CH667384B (en)
DE (1) DE3430385A1 (en)
DK (1) DK163479C (en)
ES (1) ES8506445A1 (en)
FI (1) FI85214C (en)
FR (1) FR2550706B1 (en)
GB (2) GB8322178D0 (en)
GR (1) GR80127B (en)
IE (1) IE57537B1 (en)
IL (1) IL72590A (en)
IT (1) IT1175612B (en)
LU (1) LU85512A1 (en)
NL (1) NL8402514A (en)
NZ (1) NZ209112A (en)
PT (1) PT79104B (en)
SE (1) SE459471B (en)
ZA (1) ZA846064B (en)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0158441B2 (en) * 1984-03-08 2001-04-04 Phares Pharmaceutical Research N.V. Liposome-forming composition
GB8423436D0 (en) * 1984-09-17 1984-10-24 Riker Laboratories Inc Preparation of liposomes
CA1260393A (en) * 1984-10-16 1989-09-26 Lajos Tarcsay Liposomes of synthetic lipids
GB8502892D0 (en) * 1985-02-05 1985-03-06 Sterwin Ag Aerosol composition
US5192528A (en) 1985-05-22 1993-03-09 Liposome Technology, Inc. Corticosteroid inhalation treatment method
US5340587A (en) * 1985-05-22 1994-08-23 Liposome Technology, Inc. Liposome/bronchodilator method & System
DE3686025T2 (en) * 1985-05-22 1993-01-07 Liposome Technology Inc METHOD AND SYSTEM FOR INHALING LIPOSOMES.
GB8522964D0 (en) * 1985-09-17 1985-10-23 Biocompatibles Ltd Aerosol
EP0221821A3 (en) * 1985-11-01 1988-01-27 Centre National De La Recherche Scientifique (Cnrs) New aerosol composition for in vivo imaging and therapy
IE63869B1 (en) * 1986-11-06 1995-06-14 Res Dev Foundation Aerosols containing liposomes and method for their preparation
US4897256A (en) * 1986-11-25 1990-01-30 Abbott Laboratories LHRH analog formulations
US4828837A (en) * 1987-03-30 1989-05-09 Liposome Technology, Inc. Non-crystalline minoxidil composition, its production and application
US5030442A (en) * 1987-03-30 1991-07-09 Liposome Technology, Inc. Non-crystalline minoxidil composition
JP2581920B2 (en) * 1987-05-18 1997-02-19 有限会社野々川商事 Cosmetics
FR2638639A1 (en) * 1988-11-08 1990-05-11 Parincos Parfumerie Cosmet Int Composition and method for the production of oligolamellar liposomes for the purpose of application in cosmetology and topical dermatology
JPH03193714A (en) * 1989-12-25 1991-08-23 Kobayashi Kose Co Ltd Aerosol-type cosmetic
DE4203306A1 (en) * 1992-02-06 1993-08-12 Ig Spruehtechnik Gmbh ASTHMA OR PULMONAL AEROSOL PREPARATIONS WITH LECITHIN
DE59406065D1 (en) * 1993-03-24 1998-07-02 Ciba Geigy Ag Process for the production of a liposome dispersion in the high pressure range
EP0706374B1 (en) * 1993-06-30 1997-12-10 Genentech, Inc. Method for preparing liposomes
GB9409763D0 (en) * 1994-05-16 1994-07-06 Phares Pharma Holland Liposome forming compositions
ES2111488B1 (en) * 1996-01-17 1998-11-01 Lucas Meyer S A USE OF PROLIPOSOMES COMPOSITIONS IN THE DYE, WHITENING AND SOFTENING OF THE TEXTILE INDUSTRY AND PROCEDURE FOR THE PREPARATION OF DYE BANKS FROM THESE PROLIPOSOME COMPOSITIONS.
WO1998055104A1 (en) * 1997-06-06 1998-12-10 Shionogi & Co., Ltd. Improvement in medicament administration system
WO2000000178A1 (en) * 1998-06-30 2000-01-06 Rohto Pharmaceutical Co., Ltd. Compositions containing liposomes and/or emulsions and process for the preparation thereof
IL143046A0 (en) * 1998-11-12 2002-04-21 Pilkiewicz Frank G An inhalation system
EP1839648A3 (en) * 1998-11-12 2007-11-21 Transave, Inc. An inhalation system
US7718189B2 (en) 2002-10-29 2010-05-18 Transave, Inc. Sustained release of antiinfectives
US7879351B2 (en) 2002-10-29 2011-02-01 Transave, Inc. High delivery rates for lipid based drug formulations, and methods of treatment thereof
CA2504317C (en) 2002-10-29 2012-05-22 Transave, Inc. Sustained release of antiinfectives
JP2009513621A (en) * 2005-10-26 2009-04-02 イッサム リサーチ デベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム Method for preparing liposomes and use thereof
EP3067047B1 (en) 2005-12-08 2022-04-20 Insmed Incorporated Lipid-based compositions of antiinfectives for treating pulmonary infections
CA2649025A1 (en) * 2006-04-11 2007-10-18 Wingturf Co., Ltd. Production method of liposome dispersion and production equipment thereof
US20100196455A1 (en) 2007-05-04 2010-08-05 Transave, Inc. Compositions of Multicationic Drugs for Reducing Interactions with Polyanionic Biomolecules and Methods of Use Thereof
US9333214B2 (en) 2007-05-07 2016-05-10 Insmed Incorporated Method for treating pulmonary disorders with liposomal amikacin formulations
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
JP5572636B2 (en) 2008-12-29 2014-08-13 ペトロヴィッチ グレベンニコヴ，イヴゲニー Liposome pharmaceutical production method and liposome production apparatus
RU2470624C1 (en) * 2011-08-25 2012-12-27 Евгений Петрович Гребенников Device for producing liposomal preparations
NZ719739A (en) 2012-05-21 2017-07-28 Insmed Inc Systems for treating pulmonary infections
EP3581186A1 (en) 2012-11-29 2019-12-18 Insmed Incorporated Stabilized vancomycin formulations
US20150224077A1 (en) 2014-02-10 2015-08-13 Patara Pharma, LLC Methods for the Treatment of Systemic Disorders Treatable with Mast Cell Stabilizers, including Mast Cell Related Disorders
EP3725311A1 (en) 2014-02-10 2020-10-21 Respivant Sciences GmbH Methods for the treatment of lung diseases with mast cell stabilizers
PT3142643T (en) 2014-05-15 2019-10-28 Insmed Inc Methods for treating pulmonary non-tuberculous mycobacterial infections
WO2017027402A1 (en) 2015-08-07 2017-02-16 Patara Pharma, LLC Methods for the treatment of systemic disorders treatable with mast cell stabilizers, including mast cell related disorders
EP3331522A1 (en) 2015-08-07 2018-06-13 Patara Pharma LLC Methods for the treatment of mast cell related disorders with mast cell stabilizers
CA3035528A1 (en) 2016-08-31 2018-03-08 Respivant Sciences Gmbh Cromolyn compositions for treatment of chronic cough due to idiopathic pulmonary fibrosis
JP2019531308A (en) 2016-10-07 2019-10-31 レシュピファント サイエンシス ゲゼルシャフト ミット ベシュレンクター ハフトゥングＲｅｓｐｉｖａｎｔ Ｓｃｉｅｎｃｅｓ Ｇｍｂｈ Cromolyn composition for the treatment of pulmonary fibrosis
JP7008975B2 (en) * 2017-08-31 2022-01-25 クラシエホームプロダクツ株式会社 Skin cosmetics
US11571386B2 (en) 2018-03-30 2023-02-07 Insmed Incorporated Methods for continuous manufacture of liposomal drug products
EP3958694B1 (en) * 2020-07-17 2024-06-26 KT&G Corporation Pressurization device for aerosol generating article and aerosol generating system including the same

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB780885A (en) * 1955-05-03 1957-08-07 Innoxa England Ltd Foundation cream
GB993702A (en) * 1961-11-10 1965-06-02 Takeda Chemical Industries Ltd An aerosol dispersing agent
DE1277210B (en) * 1965-09-24 1968-09-12 Revlon Self-propelling mixtures
US3326416A (en) * 1966-01-14 1967-06-20 Du Pont Apparatus for codispensing a plurality of liquids
US3325056A (en) * 1966-02-23 1967-06-13 Du Pont Apparatus for codispensing a plurality of liquids
US3338479A (en) * 1966-04-04 1967-08-29 Leonard L Marraffino Mixing head with secondary fluid adapted for connection with discharge means of primary fluid container
GB1287470A (en) * 1968-11-25 1972-08-31 Gillette Co Pressurised dispensing package
US3594476A (en) * 1969-05-12 1971-07-20 Massachusetts Inst Technology Submicron aqueous aerosols containing lecithin
NL7012832A (en) * 1970-08-29 1972-03-02
US3637114A (en) * 1970-09-03 1972-01-25 Philip Meshberg Device for codispensing two materials
GB1372721A (en) * 1971-01-16 1974-11-06 Wilkinson Sword Ltd Containers of antiseptics for the treatment of burns and scalds
DE2115926C3 (en) * 1971-04-01 1978-05-03 C.H. Boehringer Sohn, 6507 Ingelheim 1 - (4-Hydroxy-3-dimethylaminosulfamidophenyI) -2-aminoether derivatives, process for their preparation and compositions containing them
US3997467A (en) * 1971-11-26 1976-12-14 Pharmacia Aktiebolag Foam forming composition
DE2346730C3 (en) * 1973-09-17 1980-10-16 Carl Heyer Gmbh, Inhalationstechnik, 5427 Bad Ems Device for aerosol treatment of people, animals, objects, substances and the like in a treatment room
LU70720A1 (en) * 1974-08-12 1976-08-19
US4073412A (en) * 1976-06-03 1978-02-14 Blue Cross Laboratories, Inc. Emulsified cookware lubricant having freeze-thaw stability
GB1575343A (en) * 1977-05-10 1980-09-17 Ici Ltd Method for preparing liposome compositions containing biologically active compounds
GB2001334B (en) * 1977-07-19 1982-03-03 Fisons Ltd Pressurised aerosol formulation
FR2416008A1 (en) * 1978-02-02 1979-08-31 Oreal LIPOSOME LYOPHILISATES
CH646390A5 (en) * 1980-05-12 1984-11-30 Polyfill Ag Siphon.
DE3207289A1 (en) * 1982-03-01 1983-09-15 Perfect-Valois Ventil GmbH, 4600 Dortmund DISPENSING VALVE FOR AEROSOL CAN
EP0100964A3 (en) * 1982-07-31 1984-06-13 Reifenrath, Rainer, Dr. Pharmaceutical product for the treatment and prophylaxis of infections, cough and obstructive respiratory diseases, and process for preparing it
FR2543018B1 (en) * 1983-03-22 1985-07-26 Oreal PROCESS FOR THE PREPARATION OF LIPID VESICLES BY SPRAYING SOLVENTS
CH664943A5 (en) * 1983-08-16 1988-04-15 Sterwin Ag TWO-COMPONENT PACK.

Also Published As

Publication number Publication date
IE842121L (en) 1985-02-17
DK163479C (en) 1992-08-03
ES535163A0 (en) 1985-08-01
FI85214C (en) 1992-03-25
DK392884A (en) 1985-02-18
GB8420850D0 (en) 1984-09-19
GR80127B (en) 1984-12-14
FI85214B (en) 1991-12-13
ZA846064B (en) 1985-03-27
GB8322178D0 (en) 1983-09-21
NL8402514A (en) 1985-03-18
IL72590A (en) 1987-12-31
FI843223A0 (en) 1984-08-15
BE900375A (en) 1985-02-18
LU85512A1 (en) 1985-04-24
DE3430385A1 (en) 1985-03-07
DK392884D0 (en) 1984-08-16
GB2145107A (en) 1985-03-20
SE459471B (en) 1989-07-10
CH667384B (en) 1988-10-14
KR850001689A (en) 1985-04-01
PT79104A (en) 1984-09-01
ATA263684A (en) 1989-08-15
PT79104B (en) 1986-09-08
IT1175612B (en) 1987-07-15
JPS6089414A (en) 1985-05-20
IT8422357A0 (en) 1984-08-17
IL72590A0 (en) 1984-11-30
AT389993B (en) 1990-02-26
NZ209112A (en) 1988-06-30
DK163479B (en) 1992-03-09
SE8404118L (en) 1985-02-18
IE57537B1 (en) 1993-02-24
SE8404118D0 (en) 1984-08-16
GB2145107B (en) 1987-02-18
AU3178684A (en) 1985-02-21
FR2550706A1 (en) 1985-02-22
FR2550706B1 (en) 1988-09-23
AU569314B2 (en) 1988-01-28
FI843223A (en) 1985-02-18

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970203