ES8505678A1 - Procedimiento para preparar pirido (1,2-c) imidazo-(1,2-a)bencimidazoles sustituidos - Google Patents
Procedimiento para preparar pirido (1,2-c) imidazo-(1,2-a)bencimidazoles sustituidosInfo
- Publication number
- ES8505678A1 ES8505678A1 ES535875A ES535875A ES8505678A1 ES 8505678 A1 ES8505678 A1 ES 8505678A1 ES 535875 A ES535875 A ES 535875A ES 535875 A ES535875 A ES 535875A ES 8505678 A1 ES8505678 A1 ES 8505678A1
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- preparation
- pharmaceutical preparations
- substituted
- pyridoû1
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE PIRIDO(1,2-C) IMIDAZO-(1,2-A) BENCIMIDAZOLES SUSTITUIDOS Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R Y R-R PUEDEN SER VARIOS TIPOS DE RADICALES.COMPRENDE LA REACCION DE CICLACION DE COMPUESTOS DE FORMULA (II), EN LA QUE R-R TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), N VALE 0 O 1, E Y, Y Y Z PUEDEN SER VARIOS TIPOS DE RADICALES. LA CICLACION SE EFECTUA POR CALENTAMIENTO EN UN DISOLVENTE ORGANICO, EN PRESENCIA DE UN ACIDO FUERTE, A TEMPERATURA SUPERIOR A LA DE EBULLICION.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO EN LESIONES GASTROINTESTINALES.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19833333314 DE3333314A1 (de) | 1983-09-15 | 1983-09-15 | Substituierte pyrido(1,2-c)imidazo(1,2-a)benzimidazole, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8505678A1 true ES8505678A1 (es) | 1985-06-01 |
ES535875A0 ES535875A0 (es) | 1985-06-01 |
Family
ID=6209147
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES535875A Granted ES535875A0 (es) | 1983-09-15 | 1984-09-13 | Procedimiento para preparar pirido (1,2-c) imidazo-(1,2-a)bencimidazoles sustituidos |
ES540511A Expired ES8602790A1 (es) | 1983-09-15 | 1985-02-19 | Procedimiento para preparar pirido (1,2-c)imidazo-(1,2-a) bencimidazoles sustituidos |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES540511A Expired ES8602790A1 (es) | 1983-09-15 | 1985-02-19 | Procedimiento para preparar pirido (1,2-c)imidazo-(1,2-a) bencimidazoles sustituidos |
Country Status (14)
Country | Link |
---|---|
US (1) | US4585775A (es) |
EP (1) | EP0138034B1 (es) |
JP (1) | JPS6084289A (es) |
KR (1) | KR850002100A (es) |
AT (1) | ATE41775T1 (es) |
AU (1) | AU3306884A (es) |
CA (1) | CA1247621A (es) |
DE (2) | DE3333314A1 (es) |
DK (1) | DK440084A (es) |
ES (2) | ES535875A0 (es) |
GR (1) | GR80358B (es) |
HU (1) | HU194234B (es) |
PT (1) | PT79200B (es) |
ZA (1) | ZA847261B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR243167A1 (es) | 1985-08-24 | 1993-07-30 | Hoechst Ag | Procedimiento para la preparacion de toluidinas sustituidas. |
DE3639926A1 (de) * | 1986-11-22 | 1988-06-01 | Hoechst Ag | Substituierte thienoimidazoltoluidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer |
US5008282A (en) * | 1988-12-28 | 1991-04-16 | Kotobuki Seiyaku Co. Ltd. | Cyclic guanidine derivatives, anti-ulceratives and methods of manufacturing the same |
SE9500051D0 (sv) * | 1995-01-09 | 1995-01-09 | Frode Rise | Antioxidants, tissue- and/or neuroprotectants |
RU2645917C1 (ru) * | 2017-04-12 | 2018-03-01 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Ярославский государственный университет им. П.Г. Демидова" | Способ синтеза пиридо[1,2-а]имидазо[4,5-f]бензимидазола и его производных |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4821274Y1 (es) * | 1969-05-31 | 1973-06-20 | ||
JPS5124517B1 (es) * | 1971-03-15 | 1976-07-24 | ||
US3880866A (en) * | 1972-05-01 | 1975-04-29 | American Home Prod | 7-Azaindole fused heterocyclic compounds |
US3911130A (en) * | 1973-04-18 | 1975-10-07 | American Home Prod | Novel 7-azaindole fused heterocyclic compounds for producing analgesia |
US3880870A (en) * | 1973-04-18 | 1975-04-29 | American Home Prod | 7-Azaindole fused heterocyclic compounds |
SE416649B (sv) * | 1974-05-16 | 1981-01-26 | Haessle Ab | Forfarande for framstellning av foreningar som paverkar magsyrasekretionen |
SE7804231L (sv) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
GB2028317B (en) * | 1978-08-15 | 1982-11-10 | Pfizer Ltd | 2-(imidazol-1-ylmethyl)-pyridine and -quinoline thromboxane synthetase inhibitors |
US4255573A (en) * | 1979-03-29 | 1981-03-10 | Adhikary Parimal K | Imidazoindole derivatives and pharmaceutical compositions comprising imidazoindole derivatives |
JPS56116980A (en) * | 1980-02-15 | 1981-09-14 | Nippon Bulge Ind | Bend for pipings |
US4254127A (en) * | 1980-04-03 | 1981-03-03 | Janssen Pharmaceutica, N.V. | 1,3-Dihydro-1-[(1-piperidinyl)alkyl]-2H-benzimidazol-2-one derivatives |
US4472409A (en) * | 1981-11-05 | 1984-09-18 | Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung | 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects |
-
1983
- 1983-09-15 DE DE19833333314 patent/DE3333314A1/de not_active Withdrawn
-
1984
- 1984-09-06 AT AT84110589T patent/ATE41775T1/de not_active IP Right Cessation
- 1984-09-06 DE DE8484110589T patent/DE3477490D1/de not_active Expired
- 1984-09-06 EP EP84110589A patent/EP0138034B1/de not_active Expired
- 1984-09-10 HU HU843413A patent/HU194234B/hu not_active IP Right Cessation
- 1984-09-13 US US06/650,106 patent/US4585775A/en not_active Expired - Fee Related
- 1984-09-13 ES ES535875A patent/ES535875A0/es active Granted
- 1984-09-13 GR GR80358A patent/GR80358B/el unknown
- 1984-09-13 CA CA000463077A patent/CA1247621A/en not_active Expired
- 1984-09-14 KR KR1019840005595A patent/KR850002100A/ko not_active Application Discontinuation
- 1984-09-14 JP JP59191867A patent/JPS6084289A/ja active Pending
- 1984-09-14 ZA ZA847261A patent/ZA847261B/xx unknown
- 1984-09-14 AU AU33068/84A patent/AU3306884A/en not_active Abandoned
- 1984-09-14 PT PT79200A patent/PT79200B/pt unknown
- 1984-09-14 DK DK440084A patent/DK440084A/da not_active Application Discontinuation
-
1985
- 1985-02-19 ES ES540511A patent/ES8602790A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE3333314A1 (de) | 1985-03-28 |
HUT36120A (en) | 1985-08-28 |
KR850002100A (ko) | 1985-05-06 |
DK440084A (da) | 1985-03-16 |
DK440084D0 (da) | 1984-09-14 |
HU194234B (en) | 1988-01-28 |
JPS6084289A (ja) | 1985-05-13 |
AU3306884A (en) | 1985-03-21 |
EP0138034A1 (de) | 1985-04-24 |
GR80358B (en) | 1985-01-11 |
ES535875A0 (es) | 1985-06-01 |
ZA847261B (en) | 1985-05-29 |
CA1247621A (en) | 1988-12-28 |
EP0138034B1 (de) | 1989-03-29 |
ES540511A0 (es) | 1985-12-01 |
US4585775A (en) | 1986-04-29 |
PT79200A (de) | 1984-10-01 |
ES8602790A1 (es) | 1985-12-01 |
ATE41775T1 (de) | 1989-04-15 |
PT79200B (de) | 1986-09-10 |
DE3477490D1 (en) | 1989-05-03 |
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