ES8505676A1 - Procedimiento para la preparacion del fosfato del (+) 14, 15-dehidro-(3 , 16 )-eburnamenina-14-carboxilato de etilo - Google Patents

Procedimiento para la preparacion del fosfato del (+) 14, 15-dehidro-(3 , 16 )-eburnamenina-14-carboxilato de etilo

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Publication number
ES8505676A1
ES8505676A1 ES530165A ES530165A ES8505676A1 ES 8505676 A1 ES8505676 A1 ES 8505676A1 ES 530165 A ES530165 A ES 530165A ES 530165 A ES530165 A ES 530165A ES 8505676 A1 ES8505676 A1 ES 8505676A1
Authority
ES
Spain
Prior art keywords
phosphate
citrate
vinpocetine
treated
sodium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES530165A
Other languages
English (en)
Other versions
ES530165A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Covex SA
Original Assignee
Covex SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Covex SA filed Critical Covex SA
Priority to ES530165A priority Critical patent/ES530165A0/es
Priority to DE8484401984T priority patent/DE3479423D1/de
Priority to EP84401984A priority patent/EP0154756B2/fr
Priority to JP60037740A priority patent/JPH0643425B2/ja
Publication of ES8505676A1 publication Critical patent/ES8505676A1/es
Publication of ES530165A0 publication Critical patent/ES530165A0/es
Priority to US07/006,354 priority patent/US4749707A/en
Granted legal-status Critical Current

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Abstract

PROCEDIMIENTO PARA LA PREPARACION DEL FOSFATO DEL (B)14,15-DEHIDRO-(3A-16A)-EBURNAMENINA-14-CARBOXILATO DE ETILO, DE FORMULA GENERAL (I).CONSISTE EN HACER REACCIONAR EL (B)14,15-DEHIDRO-(3A,16A)-EBURNAMENINA-14-CARBOXILATO DE ETILO BASE, O UNA SAL DE ESTE, CON UNA SOLUCION ALCOHOLICA O ACUOSA DEL ACIDO FOSFORICO O DE FOSFATO SODICO, DE MANERA QUE SE SOMETE DICHA SOLUCION DE REACCION A TEMPERATURAS COMPRENDIDAS ENTRE 28 Y 60 GRADOS, DURANTE UN TIEMPO QUE VARIA ENTRE TRES Y CINCO MINUTOS.DE APLICACION EN FARMACIA Y COMO COMPUESTO INTERMEDIO EN LA OBTENCION DE OTROS TIPOS DE SALES DEL MISMO COMPUESTO.
ES530165A 1984-02-29 1984-02-29 Procedimiento para la preparacion del fosfato del (+) 14, 15-dehidro-(3 , 16 )-eburnamenina-14-carboxilato de etilo Granted ES530165A0 (es)

Priority Applications (5)

Application Number Priority Date Filing Date Title
ES530165A ES530165A0 (es) 1984-02-29 1984-02-29 Procedimiento para la preparacion del fosfato del (+) 14, 15-dehidro-(3 , 16 )-eburnamenina-14-carboxilato de etilo
DE8484401984T DE3479423D1 (en) 1984-02-29 1984-10-04 Citrate of vinpocetine, and process for its preparation
EP84401984A EP0154756B2 (fr) 1984-02-29 1984-10-04 Citrate de vinpocetine et son procédé de préparation
JP60037740A JPH0643425B2 (ja) 1984-02-29 1985-02-28 ビンポセチンのくえん酸塩及びそれを含む薬剤
US07/006,354 US4749707A (en) 1984-02-29 1987-01-14 Citric acid salt of (+) vinpocetine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES530165A ES530165A0 (es) 1984-02-29 1984-02-29 Procedimiento para la preparacion del fosfato del (+) 14, 15-dehidro-(3 , 16 )-eburnamenina-14-carboxilato de etilo

Publications (2)

Publication Number Publication Date
ES8505676A1 true ES8505676A1 (es) 1985-06-16
ES530165A0 ES530165A0 (es) 1985-06-16

Family

ID=8486956

Family Applications (1)

Application Number Title Priority Date Filing Date
ES530165A Granted ES530165A0 (es) 1984-02-29 1984-02-29 Procedimiento para la preparacion del fosfato del (+) 14, 15-dehidro-(3 , 16 )-eburnamenina-14-carboxilato de etilo

Country Status (1)

Country Link
ES (1) ES530165A0 (es)

Also Published As

Publication number Publication date
ES530165A0 (es) 1985-06-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000403