ES8504795A1 - Un procedimiento para obtener 2,5-anhidro-3,4,6-tri-o-acil-d-alonselenocarboxamida - Google Patents

Un procedimiento para obtener 2,5-anhidro-3,4,6-tri-o-acil-d-alonselenocarboxamida

Info

Publication number
ES8504795A1
ES8504795A1 ES527278A ES527278A ES8504795A1 ES 8504795 A1 ES8504795 A1 ES 8504795A1 ES 527278 A ES527278 A ES 527278A ES 527278 A ES527278 A ES 527278A ES 8504795 A1 ES8504795 A1 ES 8504795A1
Authority
ES
Spain
Prior art keywords
ribofuranosylselenazole
beta
novel
production
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES527278A
Other languages
English (en)
Other versions
ES527278A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brigham Young University
Original Assignee
Brigham Young University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham Young University filed Critical Brigham Young University
Publication of ES527278A0 publication Critical patent/ES527278A0/es
Publication of ES8504795A1 publication Critical patent/ES8504795A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D421/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having selenium, tellurium, or halogen atoms as ring hetero atoms
    • C07D421/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having selenium, tellurium, or halogen atoms as ring hetero atoms containing two hetero rings
    • C07D421/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having selenium, tellurium, or halogen atoms as ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE 2,5-ANHIDRO-3,4,6-TRI-O-ACIL-D-ALONSELENOCARBOXAMIDA, DE FORMULA (I), DONDE R1, R2 Y R3 SON ACILO Y Z ES -C(NH2)SE.MEDIANTE REACCION DEL CIANURO DE 2,3,5-TRI-O-ACIL-BBB-D-RIBOFURANOSILO CON SELENIURO DE HIDROGENO LIQUIDO, EN PRESENCIA DE CATALIZADOR DE AMINA. LAS COMPOSICIONES FARMACEUTICAS PUEDEN FORMULARSE CON EXCIPIENTES QUE PERMITAN SU APLICACION COMO INYECTABLE, POR VIA ORAL, OFTALMICA, TOPICA O EN SUPOSITORIOS.DE APLICACION COMO ANTITUMORES Y ANTIVIRALES.
ES527278A 1982-03-23 1983-11-15 Un procedimiento para obtener 2,5-anhidro-3,4,6-tri-o-acil-d-alonselenocarboxamida Expired ES8504795A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36096882A 1982-03-23 1982-03-23
US06/465,221 US4531001A (en) 1982-03-23 1983-02-15 2-β-D-ribofuranosylselenazole-4-carboxamide compounds

Publications (2)

Publication Number Publication Date
ES527278A0 ES527278A0 (es) 1985-04-16
ES8504795A1 true ES8504795A1 (es) 1985-04-16

Family

ID=27001098

Family Applications (5)

Application Number Title Priority Date Filing Date
ES520826A Granted ES520826A0 (es) 1982-03-23 1983-03-22 Un procedimiento para obtener compuestos de ribofuranosilselenazol-4-carboxamida.
ES527276A Granted ES527276A0 (es) 1982-03-23 1983-11-15 Un procedimiento para obtener compuestos de ribofuranosilselenazol-4-carboxamida-5'-fosfato
ES527277A Granted ES527277A0 (es) 1982-03-23 1983-11-15 Un procedimiento para obtener compuestos de 2'-o-acil-, 3'-o-acil-, 2',3'-di-o-acil- y 2',3',5'-tri-o-acil-2-b-d-ribofuranosilselenazol-4-carboxamida
ES527279A Expired ES8600323A1 (es) 1982-03-23 1983-11-15 Un procedimiento para obtener 2-(2,3,5-tri-o-aril-b-d-ribofuranosil)selenazol-4-carboxilatos de alcohilo o aralcohilo
ES527278A Expired ES8504795A1 (es) 1982-03-23 1983-11-15 Un procedimiento para obtener 2,5-anhidro-3,4,6-tri-o-acil-d-alonselenocarboxamida

Family Applications Before (4)

Application Number Title Priority Date Filing Date
ES520826A Granted ES520826A0 (es) 1982-03-23 1983-03-22 Un procedimiento para obtener compuestos de ribofuranosilselenazol-4-carboxamida.
ES527276A Granted ES527276A0 (es) 1982-03-23 1983-11-15 Un procedimiento para obtener compuestos de ribofuranosilselenazol-4-carboxamida-5'-fosfato
ES527277A Granted ES527277A0 (es) 1982-03-23 1983-11-15 Un procedimiento para obtener compuestos de 2'-o-acil-, 3'-o-acil-, 2',3'-di-o-acil- y 2',3',5'-tri-o-acil-2-b-d-ribofuranosilselenazol-4-carboxamida
ES527279A Expired ES8600323A1 (es) 1982-03-23 1983-11-15 Un procedimiento para obtener 2-(2,3,5-tri-o-aril-b-d-ribofuranosil)selenazol-4-carboxilatos de alcohilo o aralcohilo

Country Status (14)

Country Link
US (1) US4531001A (es)
EP (1) EP0089678B1 (es)
KR (1) KR880001869B1 (es)
AU (1) AU553665B2 (es)
CA (1) CA1209986A (es)
DE (1) DE3366378D1 (es)
DK (2) DK167765B1 (es)
ES (5) ES520826A0 (es)
FI (1) FI76574C (es)
GR (1) GR78301B (es)
IE (1) IE54520B1 (es)
NO (1) NO155842C (es)
NZ (1) NZ203649A (es)
PT (1) PT76426B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4619996A (en) * 1984-07-09 1986-10-28 Warner-Lambert Company Process for preparing 2-β-D-ribofuranosylselenazole-4-carboxamide
US4801698A (en) * 1986-08-15 1989-01-31 Warner-Lambert Company Process for preparing diaminopyrimido(4,5-d)pyrimidine glycoside and glycotide
US5438131A (en) * 1992-09-16 1995-08-01 Bergstrom; Donald E. 3-nitropyrrole nucleoside
GB9307043D0 (en) * 1993-04-05 1993-05-26 Norsk Hydro As Chemical compounds
WO1996026212A1 (en) * 1995-02-17 1996-08-29 Icn Pharmaceuticals, Inc. Procedures for obtaining ribo-c-nucleosides
EP1000075A4 (en) * 1997-06-30 2001-09-05 Icn Pharmaceuticals PROCESS FOR PRODUCING TIAZOFURINE AND OTHER C-NUCLEOSIDES

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3423399A (en) * 1966-06-09 1969-01-21 Takeda Chemical Industries Ltd Method for the production of 5'-ribonucleotide
US3984396A (en) * 1971-06-01 1976-10-05 Icn Pharmaceuticals, Inc. 1-(β,-D-ribofuranosyl)-1,2,4-triazole acid esters
US3798209A (en) * 1971-06-01 1974-03-19 Icn Pharmaceuticals 1,2,4-triazole nucleosides

Also Published As

Publication number Publication date
KR840004126A (ko) 1984-10-06
NZ203649A (en) 1985-02-28
ES527279A0 (es) 1985-10-01
PT76426A (en) 1983-04-01
AU553665B2 (en) 1986-07-24
EP0089678A1 (en) 1983-09-28
ES8404373A1 (es) 1984-05-01
FI76574C (fi) 1988-11-10
NO831012L (no) 1983-09-26
DE3366378D1 (en) 1986-10-30
DK172165B1 (da) 1997-12-08
EP0089678B1 (en) 1986-09-24
DK25093D0 (da) 1993-03-08
ES8600322A1 (es) 1985-10-01
PT76426B (en) 1986-02-04
ES520826A0 (es) 1984-05-01
KR880001869B1 (ko) 1988-09-23
FI830941L (fi) 1983-09-24
ES8600321A1 (es) 1985-10-01
DK167765B1 (da) 1993-12-13
FI76574B (fi) 1988-07-29
US4531001A (en) 1985-07-23
ES8600323A1 (es) 1985-10-01
ES527277A0 (es) 1985-10-01
NO155842C (no) 1987-06-10
FI830941A0 (fi) 1983-03-22
CA1209986A (en) 1986-08-19
DK129983A (da) 1983-09-24
ES527278A0 (es) 1985-04-16
AU1269383A (en) 1983-09-29
GR78301B (es) 1984-09-26
IE54520B1 (en) 1989-11-08
DK25093A (da) 1993-03-08
ES527276A0 (es) 1985-10-01
DK129983D0 (da) 1983-03-22
NO155842B (no) 1987-03-02
IE830580L (en) 1983-09-23

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20040119