ES8504673A1 - Un procedimiento para preparar peptidos. - Google Patents
Un procedimiento para preparar peptidos.Info
- Publication number
- ES8504673A1 ES8504673A1 ES523277A ES523277A ES8504673A1 ES 8504673 A1 ES8504673 A1 ES 8504673A1 ES 523277 A ES523277 A ES 523277A ES 523277 A ES523277 A ES 523277A ES 8504673 A1 ES8504673 A1 ES 8504673A1
- Authority
- ES
- Spain
- Prior art keywords
- arg
- ala
- gln
- leu
- ser
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 241000124008 Mammalia Species 0.000 abstract 2
- 230000004936 stimulating effect Effects 0.000 abstract 2
- WVRUNFYJIHNFKD-WDSKDSINSA-N Arg-Ala Chemical compound OC(=O)[C@H](C)NC(=O)[C@@H](N)CCCN=C(N)N WVRUNFYJIHNFKD-WDSKDSINSA-N 0.000 abstract 1
- SGYSTDWPNPKJPP-GUBZILKMSA-N Arg-Ala-Arg Chemical compound NC(=N)NCCC[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O SGYSTDWPNPKJPP-GUBZILKMSA-N 0.000 abstract 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 abstract 1
- 238000007792 addition Methods 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 230000001817 pituitary effect Effects 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
- A23K20/147—Polymeric derivatives, e.g. peptides or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/12—Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Polymers & Plastics (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Animal Husbandry (AREA)
- Food Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR PEPTIDOS DEFINIDOS POR LA FORMULA (I) O FRAGMENTOS BIOLOGICAMENTE ACTIVOS DE LOS MISMOS O SUS SALES NO TOXICAS.COMPRENDE LAS SIGUIENTES OPERACIONES: PRIMERA, SE COPULAN AMINOACIDOS O PEPTIDOS CORTOS ENTRE SI, PARA FORMAR UN COMPUESTO INTERMEDIO DE CADENA LINEAL QUE RESPONDE A LA FORMULA (II); SEGUNDA, SE ELIMINAN EL GRUPO PROTECTOR O GRUPOS PROTECTORES DE DICHO COMPUESTO DE FORMULA (II), POR TRATAMIENTO CON HF O CON UN EQUIVALENTE DEL MISMO; Y POR ULTIMO, OPCIONALMENTE SE CONVIERTE EL PEPTIDO RESULTANTE EN UNA DE SUS SALES DE ADICION NO TOXICAS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8200812 | 1982-06-16 | ||
US06/418,248 US4517181A (en) | 1982-09-15 | 1982-09-15 | Mammalian PGRF |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8504673A1 true ES8504673A1 (es) | 1985-04-16 |
ES523277A0 ES523277A0 (es) | 1985-04-16 |
Family
ID=26766557
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES523277A Granted ES523277A0 (es) | 1982-06-16 | 1983-06-15 | Un procedimiento para preparar peptidos. |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0107890B1 (es) |
KR (1) | KR900006711B1 (es) |
AU (1) | AU548590B2 (es) |
CA (1) | CA1247599A (es) |
DD (1) | DD217808A5 (es) |
ES (1) | ES523277A0 (es) |
FI (1) | FI79716C (es) |
GR (1) | GR78614B (es) |
IL (1) | IL68893A0 (es) |
NO (1) | NO166486C (es) |
NZ (1) | NZ204456A (es) |
PH (1) | PH21001A (es) |
PT (1) | PT76843B (es) |
SU (1) | SU1531857A3 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4518586A (en) * | 1983-01-13 | 1985-05-21 | The Salk Institute For Biological Studies | GRF Analogs III |
US4581168A (en) * | 1983-02-21 | 1986-04-08 | Sanofi | Synthesis of hpGRF (Somatocrinin) in liquid phase and intermediate peptides |
AU575843B2 (en) * | 1983-08-10 | 1988-08-11 | The Administrators Of The Tulane Eductional Fund | Growth hormone releasing peptides |
PT79094B (en) * | 1983-08-29 | 1986-08-14 | Salk Inst For Biological Studi | Grf analogs |
FR2567524B1 (fr) * | 1984-07-10 | 1987-11-27 | Sanofi Sa | Procede de synthese de la somatocrinine en phase liquide et peptides intermediaires |
CA1271600A (en) * | 1985-01-07 | 1990-07-10 | David Howard Coy | Growth hormone-releasing peptides and method of treating mammals therewith |
FR2599038B1 (fr) * | 1986-05-26 | 1990-06-29 | Sanofi Sa | Procede de preparation de nonacosapeptides et peptides intermediaires |
-
1983
- 1983-06-02 NZ NZ204456A patent/NZ204456A/en unknown
- 1983-06-06 IL IL68893A patent/IL68893A0/xx not_active IP Right Cessation
- 1983-06-09 PT PT76843A patent/PT76843B/pt unknown
- 1983-06-10 GR GR71635A patent/GR78614B/el unknown
- 1983-06-14 PH PH29053A patent/PH21001A/en unknown
- 1983-06-14 NO NO832148A patent/NO166486C/no not_active IP Right Cessation
- 1983-06-15 ES ES523277A patent/ES523277A0/es active Granted
- 1983-06-15 SU SU833611593A patent/SU1531857A3/ru active
- 1983-06-15 FI FI832176A patent/FI79716C/fi not_active IP Right Cessation
- 1983-06-15 KR KR1019830002655A patent/KR900006711B1/ko not_active IP Right Cessation
- 1983-06-15 DD DD83252054A patent/DD217808A5/de not_active IP Right Cessation
- 1983-06-16 AU AU15843/83A patent/AU548590B2/en not_active Expired
- 1983-06-16 EP EP83303490A patent/EP0107890B1/en not_active Expired
- 1983-06-16 CA CA000430533A patent/CA1247599A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DD217808A5 (de) | 1985-01-23 |
FI79716B (fi) | 1989-10-31 |
PH21001A (en) | 1987-06-22 |
KR900006711B1 (ko) | 1990-09-17 |
PT76843A (en) | 1983-07-01 |
NZ204456A (en) | 1987-05-29 |
FI832176L (fi) | 1983-12-17 |
EP0107890B1 (en) | 1986-01-29 |
PT76843B (en) | 1986-01-15 |
AU1584383A (en) | 1983-12-22 |
FI832176A0 (fi) | 1983-06-15 |
CA1247599A (en) | 1988-12-28 |
NO832148L (no) | 1983-12-19 |
ES523277A0 (es) | 1985-04-16 |
SU1531857A3 (ru) | 1989-12-23 |
NO166486B (no) | 1991-04-22 |
EP0107890A1 (en) | 1984-05-09 |
FI79716C (fi) | 1990-02-12 |
GR78614B (es) | 1984-09-27 |
KR840006328A (ko) | 1984-11-29 |
NO166486C (no) | 1991-07-31 |
IL68893A0 (en) | 1983-10-31 |
AU548590B2 (en) | 1985-12-19 |
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