ES8503512A1 - Complejos de prostaglandinas - Google Patents
Complejos de prostaglandinasInfo
- Publication number
- ES8503512A1 ES8503512A1 ES529483A ES529483A ES8503512A1 ES 8503512 A1 ES8503512 A1 ES 8503512A1 ES 529483 A ES529483 A ES 529483A ES 529483 A ES529483 A ES 529483A ES 8503512 A1 ES8503512 A1 ES 8503512A1
- Authority
- ES
- Spain
- Prior art keywords
- complexes
- prostaglandins
- crosspovidone
- dextrans
- medicaments
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE FORMULACIONES ESTABLES DE COMPLEJOS DE PORTSGLANDINAS, DE FORMULA GENERAL (I).CONSISTE EN HACER REACCIONAR UNA SOLUCION DE PROSTAGLANDINA CON CROSSPOVIDONA, ALMIDON PRE-EMPASTADO O DEXTRANOS, EN UNA CANTIDAD TAL QUE LA RELACION PONDERAL DE PROSTAGLANDINA A CROSSPOVIDONA, ALMIDON PRE-EMPASTADO O DEXTRANOS, ESTE COMPRENDIDA ENTRE 1:1 Y 1:10.000. EL PRODUCTO OBTENIDO SE SECA CUIDADOSAMENTE EN UN TAMBOR DE VACIO.DE APLICACION EN EL TRATAMIENTO DE LA HIPERTENSION, EL ASMA BRONQUIAL, LAS ULCERAS GASTROINTESTINALES Y LAS TROMBOSIS.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19833304867 DE3304867A1 (de) | 1983-02-12 | 1983-02-12 | Absorbate von prostaglandinen |
DE19833304864 DE3304864A1 (de) | 1983-02-12 | 1983-02-12 | Adsorbate von prostaglandinen |
DE19833304880 DE3304880A1 (de) | 1983-02-12 | 1983-02-12 | Adsorbate von prostaglandinen |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8503512A1 true ES8503512A1 (es) | 1985-03-01 |
ES529483A0 ES529483A0 (es) | 1985-03-01 |
Family
ID=27190758
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES529483A Granted ES529483A0 (es) | 1983-02-12 | 1984-02-06 | Complejos de prostaglandinas |
Country Status (14)
Country | Link |
---|---|
US (1) | US4675182A (es) |
EP (1) | EP0116358B1 (es) |
KR (1) | KR880002138B1 (es) |
AU (1) | AU572115B2 (es) |
CA (1) | CA1248524A (es) |
DE (1) | DE3470663D1 (es) |
DK (1) | DK61684A (es) |
ES (1) | ES529483A0 (es) |
GR (1) | GR79806B (es) |
HU (1) | HU196127B (es) |
IE (1) | IE56766B1 (es) |
IL (1) | IL70913A (es) |
PH (1) | PH25606A (es) |
PT (1) | PT78054B (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4681759A (en) * | 1985-05-08 | 1987-07-21 | Ortho Pharmaceutical Corporation | Rioprostil-PVP complex |
IE59361B1 (en) * | 1986-01-24 | 1994-02-09 | Akzo Nv | Pharmaceutical preparation for obtaining a highly viscous hydrogel or suspension |
JPH03220201A (ja) * | 1988-11-18 | 1991-09-27 | Eisai Co Ltd | プロスタグランジン類と多糖類の結合体 |
AU8285991A (en) * | 1990-07-26 | 1992-02-18 | G.D. Searle & Co. | Polymeric drug delivery system |
US7289084B2 (en) | 2005-02-22 | 2007-10-30 | John Michael Lesniak | Computer display apparatus |
US8455547B2 (en) * | 2008-02-05 | 2013-06-04 | Allergan, Inc. | Substituted cyclopentanes having prostaglandin activity |
US7732443B2 (en) * | 2008-03-18 | 2010-06-08 | Yariv Donde | Therapeutic substituted cyclopentanes |
BRPI0912193A2 (pt) * | 2008-05-09 | 2015-10-06 | Allergan Inc | compostos terapêuticos. |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3826823A (en) * | 1972-09-25 | 1974-07-30 | Syntex Inc | Stabilized prostaglandin preparations |
US4036954A (en) * | 1973-11-02 | 1977-07-19 | Yamanouchi Pharmaceutical Co., Ltd. | Stable prostaglandin E group-containing formulation |
IT1044797B (it) * | 1974-10-15 | 1980-04-21 | Ferruti Paolo | Alti polimeri contenenti radicali prostaglandinici processo per la loro preparazione e loro impiego |
DE2515001C2 (de) * | 1975-04-04 | 1986-10-02 | Schering AG, 1000 Berlin und 4709 Bergkamen | Prostaglandin enthaltende gefriergetrocknete Pulver |
AU524104B2 (en) * | 1978-10-12 | 1982-09-02 | Toray Industries, Inc. | Stabilized prostaglandin e composition |
SE431821B (sv) * | 1979-01-29 | 1984-03-05 | Perstorp Ab | Lagringsstabilt, prostaglandininnehallande medicinskt preparat |
US4211793A (en) * | 1979-03-19 | 1980-07-08 | American Cyanamid Company | Triethyl citrate solutions of PGE-type compounds |
US4301146A (en) * | 1980-07-29 | 1981-11-17 | G. D. Searle & Co. | Stabilization of 16-oxygenated prostanoic acid derivatives |
US4370348A (en) * | 1981-06-03 | 1983-01-25 | Ortho Pharmaceutical Corporation | Method of inducing cytoprotection |
-
1984
- 1984-01-27 US US06/574,789 patent/US4675182A/en not_active Expired - Fee Related
- 1984-02-02 PT PT78054A patent/PT78054B/pt not_active IP Right Cessation
- 1984-02-06 ES ES529483A patent/ES529483A0/es active Granted
- 1984-02-06 DE DE8484101169T patent/DE3470663D1/de not_active Expired
- 1984-02-06 EP EP84101169A patent/EP0116358B1/de not_active Expired
- 1984-02-08 AU AU24286/84A patent/AU572115B2/en not_active Ceased
- 1984-02-09 IL IL70913A patent/IL70913A/xx unknown
- 1984-02-10 IE IE313/84A patent/IE56766B1/xx unknown
- 1984-02-10 HU HU84540A patent/HU196127B/hu not_active IP Right Cessation
- 1984-02-10 PH PH30225A patent/PH25606A/en unknown
- 1984-02-10 DK DK61684A patent/DK61684A/da not_active Application Discontinuation
- 1984-02-10 CA CA000447149A patent/CA1248524A/en not_active Expired
- 1984-02-10 GR GR73782A patent/GR79806B/el unknown
- 1984-02-11 KR KR8400656A patent/KR880002138B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU2428684A (en) | 1984-08-16 |
HU196127B (en) | 1988-10-28 |
AU572115B2 (en) | 1988-05-05 |
PT78054B (en) | 1986-03-20 |
IE56766B1 (en) | 1991-12-04 |
GR79806B (es) | 1984-10-31 |
KR850000391A (ko) | 1985-02-27 |
EP0116358A1 (de) | 1984-08-22 |
US4675182A (en) | 1987-06-23 |
DK61684D0 (da) | 1984-02-10 |
CA1248524A (en) | 1989-01-10 |
ES529483A0 (es) | 1985-03-01 |
PH25606A (en) | 1991-08-08 |
DE3470663D1 (en) | 1988-06-01 |
EP0116358B1 (de) | 1988-04-27 |
DK61684A (da) | 1984-08-13 |
IL70913A0 (en) | 1984-05-31 |
PT78054A (en) | 1984-03-01 |
KR880002138B1 (en) | 1988-10-17 |
IL70913A (en) | 1987-03-31 |
IE840313L (en) | 1984-08-12 |
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