ES8501385A1 - Procedimiento de preparacion de nuevos acidos 4'-flavonocarboxilicos, asi como sus derivados de la funcion acida carboxilica farmaceuticamente aceptables - Google Patents

Procedimiento de preparacion de nuevos acidos 4'-flavonocarboxilicos, asi como sus derivados de la funcion acida carboxilica farmaceuticamente aceptables

Info

Publication number
ES8501385A1
ES8501385A1 ES530889A ES530889A ES8501385A1 ES 8501385 A1 ES8501385 A1 ES 8501385A1 ES 530889 A ES530889 A ES 530889A ES 530889 A ES530889 A ES 530889A ES 8501385 A1 ES8501385 A1 ES 8501385A1
Authority
ES
Spain
Prior art keywords
image
products
carbon atoms
flavonecarboxylic
acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES530889A
Other languages
English (en)
Other versions
ES530889A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cortial SA
Original Assignee
Cortial SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cortial SA filed Critical Cortial SA
Publication of ES530889A0 publication Critical patent/ES530889A0/es
Publication of ES8501385A1 publication Critical patent/ES8501385A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE ACIDOS 4K-FLAVONOCARBOXILICOS Y DE SUS DERIVADOS DE LA FUNCION ACIDO CARBOXILICO FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R1 Y R2 PUEDEN SER VARIOS RADICALES.CONSISTE EN LA REACCION DE CLORURO DEL ACIDO PARAMETOXICARBONILBENZOICO CON UN COMPUESTO DE FORMULA (II), EN LA QUE R1 Y R2 SON LOS MISMOS QUE EN LA FORMULA (I), POR TRATAMIENTO DE LA MEZCLA A LA TEMPERATURA DE REFLUJO.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SUS ACTIVIDADES ANTIANAFILACTICAS.
ES530889A 1983-03-24 1984-03-22 Procedimiento de preparacion de nuevos acidos 4'-flavonocarboxilicos, asi como sus derivados de la funcion acida carboxilica farmaceuticamente aceptables Expired ES8501385A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8305013A FR2543140B1 (fr) 1983-03-24 1983-03-24 Nouveaux acides flavone-carboxyliques-4', leur methode de preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
ES530889A0 ES530889A0 (es) 1984-11-16
ES8501385A1 true ES8501385A1 (es) 1984-11-16

Family

ID=9287281

Family Applications (1)

Application Number Title Priority Date Filing Date
ES530889A Expired ES8501385A1 (es) 1983-03-24 1984-03-22 Procedimiento de preparacion de nuevos acidos 4'-flavonocarboxilicos, asi como sus derivados de la funcion acida carboxilica farmaceuticamente aceptables

Country Status (11)

Country Link
US (1) US4600788A (es)
EP (1) EP0125195B1 (es)
JP (1) JPS59181273A (es)
CA (1) CA1250840A (es)
DE (1) DE3466539D1 (es)
ES (1) ES8501385A1 (es)
FR (1) FR2543140B1 (es)
MA (1) MA20068A1 (es)
OA (1) OA07684A (es)
PT (1) PT78275B (es)
ZA (1) ZA842208B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62215581A (ja) * 1986-03-18 1987-09-22 Koichi Shiyudo フラボンカルボン酸誘導体
JPH0753725B2 (ja) * 1987-10-08 1995-06-07 富山化学工業株式会社 ４ｈ―１―ベンゾピラン―４―オン誘導体およびその塩、それらの製造法並びにそれらを含有する抗炎症剤
GB8804016D0 (en) * 1988-02-22 1988-03-23 Boots Co Plc Therapeutic agents
GB9604709D0 (en) * 1996-03-05 1996-05-01 Imperial College A compound
GB9603325D0 (en) 1996-02-16 1996-04-17 Imperial College A compound
US6506792B1 (en) 1997-03-04 2003-01-14 Sterix Limited Compounds that inhibit oestrone sulphatase and/or aromatase and methods for making and using
US20060241173A1 (en) * 1996-02-16 2006-10-26 Sterix Ltd. Compound
US6921776B1 (en) 1996-02-16 2005-07-26 Sterix Limited Compound
JP2000506161A (ja) * 1996-03-05 2000-05-23 インペリアル カレッジ オブ サイエンス テクノロジー アンド メディシン スルファメート基を有する化合物
GB9807779D0 (en) 1998-04-09 1998-06-10 Ciba Geigy Ag Organic compounds
FR2815033B1 (fr) 2000-10-06 2003-09-05 Negma Lab Derives de 7-carboxy-flavones, porcede pour leur preparation et leur application en therapeutique
CN102391258B (zh) * 2011-09-13 2014-09-24 中山大学 氨基取代的黄酮类化合物及其制备方法和应用
TWI583677B (zh) * 2012-09-21 2017-05-21 日本臟器製藥股份有限公司 香豆素衍生物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH471113A (de) * 1965-01-29 1969-04-15 Merck Ag E Verfahren zur Herstellung von wasserlöslichen Flavanoidderivaten
GB1461777A (en) * 1973-06-08 1977-01-19 Fisons Ltd 2-phenyl-4-oxo-4h-1-benzopyran derivatives
NZ193316A (en) * 1979-04-10 1984-07-31 Hoffmann La Roche 3-alkoxyflavone derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
ES530889A0 (es) 1984-11-16
OA07684A (fr) 1985-05-23
US4600788A (en) 1986-07-15
MA20068A1 (fr) 1984-10-01
JPS59181273A (ja) 1984-10-15
CA1250840A (en) 1989-03-07
FR2543140A1 (fr) 1984-09-28
PT78275B (fr) 1986-04-21
EP0125195A1 (fr) 1984-11-14
DE3466539D1 (en) 1987-11-05
EP0125195B1 (fr) 1987-09-30
FR2543140B1 (fr) 1985-06-21
ZA842208B (en) 1984-10-31
PT78275A (fr) 1984-04-01

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960506