ES8405621A1 - Una inmunopreparacion tumoral. - Google Patents

Una inmunopreparacion tumoral.

Info

Publication number
ES8405621A1
ES8405621A1 ES521279A ES521279A ES8405621A1 ES 8405621 A1 ES8405621 A1 ES 8405621A1 ES 521279 A ES521279 A ES 521279A ES 521279 A ES521279 A ES 521279A ES 8405621 A1 ES8405621 A1 ES 8405621A1
Authority
ES
Spain
Prior art keywords
plasma
tumor
prepared
compositions
normal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES521279A
Other languages
English (en)
Other versions
ES521279A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baylor College of Medicine
Original Assignee
Baylor College of Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baylor College of Medicine filed Critical Baylor College of Medicine
Publication of ES8405621A1 publication Critical patent/ES8405621A1/es
Publication of ES521279A0 publication Critical patent/ES521279A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/16Blood plasma; Blood serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6851Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

METODO PARA LA PRODUCCION DE UNA INMUNOPREPARACION TUMORAL.CONSISTE EN: A) SOMETER EL PLASMA, PROCEDENTE DE UNA PERSONA NORMAL O PORTADOR DE UN TUMOR Y CON LAS SIGUIENTES PROPIEDADES: 1) CONSTITUIDO POR IGC E IGM; 2) SE PRODUCE UNION A CLQ EN LAS FRACCIONES QUE SEDIMENTAN MAS ALLA DE 7S EN UN GRADIENTE DE DENSIDADES DE SACAROSA; 3) PRODUCE REACCIONES TUMORICIDAS AL INFUNDIRSE EN LA PERSONA PORTADORA; 4) PRESENTA MENORES NIVELES DE IGC, IGM E INMUNOCOMPLEJOS Y MAYOR UNION A CLQ QUE EL EFLUENTE DE INMUNOGLOBULINA ENRIQUECIDA NO TRATADO; Y 5) PRESENTA TITULOS DE ANTICUERPOS DEL TUMOR SUPERIORES A 20.000 CUANDO PROCEDE DE UNA PERSONA PORTADORA DEL TUMOR, A UN CAMPO ELECTRICO Y A UNA CORRIENTE PARA OBTENER A PARTIR DEL PLASMA UN EFLUENTE CON UNA FRACCION ENRIQUECIDA QUE CONTIENE INMUNOGLOBULINAS; B) SOMETER EL EFLUENTE A ACIDULACION O A ALCALINIZACION PARA DISOCIAR LOS COMPLEJOS ANTIGENOS-ANTICUERPO Y LIBERAR ASI LOS ANTICUERPOS ESPECIFICOS DEL TUMOR; C) NEUTRALIZAR EL EFLUENTE; Y D) FILTRAR ELEFLUENTE PARA SEPARARLO DE LOS PRECIPITADOS.TIENE APLICACION PARA EL TRATAMIENTO DEL CANCER COMO LINFOMAS Y TUMORES SOLIDOS.
ES521279A 1982-04-07 1983-04-06 Una inmunopreparacion tumoral. Granted ES521279A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36643682A 1982-04-07 1982-04-07
US47236283A 1983-03-11 1983-03-11

Publications (2)

Publication Number Publication Date
ES8405621A1 true ES8405621A1 (es) 1984-06-16
ES521279A0 ES521279A0 (es) 1984-06-16

Family

ID=27003359

Family Applications (5)

Application Number Title Priority Date Filing Date
ES521279A Granted ES521279A0 (es) 1982-04-07 1983-04-06 Una inmunopreparacion tumoral.
ES528121A Expired ES8601703A1 (es) 1982-04-07 1983-12-16 Un metodo de produccion de una preparacion de proteina a-igg
ES528118A Granted ES528118A0 (es) 1982-04-07 1983-12-16 Un metodo de produccion de una preparacion de inmunoglobulina tumoral
ES528120A Granted ES528120A0 (es) 1982-04-07 1983-12-16 Un metodo de produccion de una preparacion de plasma activada con zymosan
ES528119A Granted ES528119A0 (es) 1982-04-07 1983-12-16 Un metodo de produccion de una preparacion de proteina a-igg

Family Applications After (4)

Application Number Title Priority Date Filing Date
ES528121A Expired ES8601703A1 (es) 1982-04-07 1983-12-16 Un metodo de produccion de una preparacion de proteina a-igg
ES528118A Granted ES528118A0 (es) 1982-04-07 1983-12-16 Un metodo de produccion de una preparacion de inmunoglobulina tumoral
ES528120A Granted ES528120A0 (es) 1982-04-07 1983-12-16 Un metodo de produccion de una preparacion de plasma activada con zymosan
ES528119A Granted ES528119A0 (es) 1982-04-07 1983-12-16 Un metodo de produccion de una preparacion de proteina a-igg

Country Status (13)

Country Link
EP (1) EP0091784B1 (es)
AU (2) AU569467B2 (es)
CA (1) CA1230555A (es)
DE (1) DE3374756D1 (es)
DK (1) DK154283A (es)
ES (5) ES521279A0 (es)
FI (1) FI831169L (es)
GB (2) GB2119803B (es)
GR (1) GR78514B (es)
NO (5) NO831223L (es)
PT (1) PT76505B (es)
RO (3) RO89498A (es)
ZW (1) ZW7583A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2161813B (en) * 1984-07-20 1988-07-13 Michiko Koga Anti-tumor agent
GB9013872D0 (en) * 1990-06-21 1990-08-15 Inst Tecnologico Y Cientifico Use of protein a and polypeptide components thereof in the treatment of tumours
AU6498494A (en) * 1993-04-08 1994-11-08 Board Of Regents, The University Of Texas System Model for gonococcal infection
GB2422311A (en) * 2005-01-20 2006-07-26 Martin Lister Treatment of blood to cure disease
DE102005012594A1 (de) 2005-03-18 2006-09-21 Bayer Technology Services Gmbh Elektrofiltrationsverfahren
MX2011012094A (es) * 2009-05-14 2012-03-26 Oatmeal Biotechnologies Group L L C Tecnologias de plataforma para enfermedades que se presentan espontaneamente.
EP4353320A3 (en) * 2016-04-28 2024-05-15 Alkahest, Inc. Blood plasma and plasma fractions as therapy for tumor growth and progression

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4132769A (en) * 1974-10-30 1979-01-02 Osther Kurt B Cancer antigen, cancer therapy, and cancer diagnosis
US4146603A (en) * 1977-02-18 1979-03-27 Research Corporation Tumor specific glycoproteins and method for detecting tumorigenic cancers
FI791551A (fi) * 1978-05-17 1979-11-18 Benzon As Alfred Renad cancer associerad protein

Also Published As

Publication number Publication date
NO831223L (no) 1983-10-10
RO86661B (ro) 1985-03-01
FI831169A0 (fi) 1983-04-06
RO89496A (ro) 1986-06-30
AU1286583A (en) 1983-10-13
ZW7583A1 (en) 1983-06-29
GB2119803A (en) 1983-11-23
ES8503953A1 (es) 1985-04-16
GB2163164B (en) 1986-09-03
NO841498L (no) 1983-10-10
DK154283D0 (da) 1983-04-07
NO841495L (no) 1983-10-10
EP0091784A2 (en) 1983-10-19
ES8503950A1 (es) 1985-04-16
ES8503954A1 (es) 1985-04-16
FI831169L (fi) 1983-10-08
GB8510892D0 (en) 1985-06-05
GR78514B (es) 1984-09-27
ES521279A0 (es) 1984-06-16
EP0091784A3 (en) 1984-07-11
ES528121A0 (es) 1985-11-01
DK154283A (da) 1983-10-08
RO86661A (ro) 1986-07-30
ES8601703A1 (es) 1985-11-01
GB2119803B (en) 1986-09-03
CA1230555A (en) 1987-12-22
ES528118A0 (es) 1985-04-16
DE3374756D1 (en) 1988-01-14
RO89498A (ro) 1986-06-30
AU569467B2 (en) 1988-02-04
EP0091784B1 (en) 1987-12-02
PT76505B (en) 1986-05-05
AU1560088A (en) 1988-10-27
ES528120A0 (es) 1985-04-16
GB8309348D0 (en) 1983-05-11
PT76505A (en) 1983-05-01
GB2163164A (en) 1986-02-19
NO841496L (no) 1983-10-10
ES528119A0 (es) 1985-04-16
NO841497L (no) 1983-10-10

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