ES8403855A1 - "procedimiento para la preparacion de 1-(2,4-diclorofenoxi)-3-(3,4-dimetoxi-b-fenetilamino)-propanol-(2) racemico y opticamente activo". - Google Patents

"procedimiento para la preparacion de 1-(2,4-diclorofenoxi)-3-(3,4-dimetoxi-b-fenetilamino)-propanol-(2) racemico y opticamente activo".

Info

Publication number
ES8403855A1
ES8403855A1 ES516723A ES516723A ES8403855A1 ES 8403855 A1 ES8403855 A1 ES 8403855A1 ES 516723 A ES516723 A ES 516723A ES 516723 A ES516723 A ES 516723A ES 8403855 A1 ES8403855 A1 ES 8403855A1
Authority
ES
Spain
Prior art keywords
phenethylamino
dichlorophenoxy
dimethoxy
beta
propan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES516723A
Other languages
English (en)
Other versions
ES516723A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AWD Pharma GmbH and Co KG
Original Assignee
Arzneimittelwerk Dresden GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arzneimittelwerk Dresden GmbH filed Critical Arzneimittelwerk Dresden GmbH
Publication of ES516723A0 publication Critical patent/ES516723A0/es
Publication of ES8403855A1 publication Critical patent/ES8403855A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/60—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE 1-(2,4-DICLOROFENOXI)- 3-(3,4-DIMETOXI-B-FENETILAMINO)-PROPANOL-2 RACEMICO Y OPTICAMENTE ACTIVO, ASI COMO DE SUS ESTERES Y SALES DE ADICION DE ACIDO, DE FORMULA (I).CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), EN LAS QUE X ES EL GRUPO AMINO-NH2 O UN HALOGENO, TAL COMO CLORO, Y R PUEDE SER VARIOS TIPOS DE RADICALES. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO INERTE, EN PRESENCIA DE UNA BASE, A UNA TEMPERATURA COMPRENDIDA ENTRE 20JC Y 200JC.ESTOS COMPUESTOS TIENEN APLICACIONESFARMACOLOGICAS COMO AGENTE ANTIHIPERTENSIVO, ANTIARRITMICO Y CARDIOPROTECTOR.
ES516723A 1981-10-21 1982-10-21 "procedimiento para la preparacion de 1-(2,4-diclorofenoxi)-3-(3,4-dimetoxi-b-fenetilamino)-propanol-(2) racemico y opticamente activo". Expired ES8403855A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DD81234259A DD204248A1 (de) 1981-10-21 1981-10-21 Verfahren zur herstellung von 1-(2,4-dichlorphenoxy)-3 (3,4-dimethoxy-beta-phenethylamino)-propanol-(2)

Publications (2)

Publication Number Publication Date
ES516723A0 ES516723A0 (es) 1984-05-01
ES8403855A1 true ES8403855A1 (es) 1984-05-01

Family

ID=5534243

Family Applications (3)

Application Number Title Priority Date Filing Date
ES516723A Expired ES8403855A1 (es) 1981-10-21 1982-10-21 "procedimiento para la preparacion de 1-(2,4-diclorofenoxi)-3-(3,4-dimetoxi-b-fenetilamino)-propanol-(2) racemico y opticamente activo".
ES529193A Granted ES529193A0 (es) 1981-10-21 1984-01-26 Procedimiento para la preparacion de 1-(2, 4-diclorofenoxi)-3-(3, 4-dimetoxi-b-fenetilamino)-propanol-(2) racemico y opticamente activo
ES529192A Granted ES529192A0 (es) 1981-10-21 1984-01-26 Procedimiento para la preparacion de 1-(2,4-diciclorofenoxi)-3-(3,4-dimetoxi-b-fenetilamino)-propanol-2 racemico y op- ticamente activo.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES529193A Granted ES529193A0 (es) 1981-10-21 1984-01-26 Procedimiento para la preparacion de 1-(2, 4-diclorofenoxi)-3-(3, 4-dimetoxi-b-fenetilamino)-propanol-(2) racemico y opticamente activo
ES529192A Granted ES529192A0 (es) 1981-10-21 1984-01-26 Procedimiento para la preparacion de 1-(2,4-diciclorofenoxi)-3-(3,4-dimetoxi-b-fenetilamino)-propanol-2 racemico y op- ticamente activo.

Country Status (14)

Country Link
EP (1) EP0086256B1 (es)
JP (1) JPS58131946A (es)
AT (1) ATE15031T1 (es)
BG (1) BG40396A1 (es)
CS (1) CS247552B1 (es)
DD (1) DD204248A1 (es)
DE (1) DE3265640D1 (es)
DK (1) DK154209C (es)
ES (3) ES8403855A1 (es)
FI (1) FI79296C (es)
HU (1) HU190994B (es)
NO (1) NO155052C (es)
SU (1) SU1507763A1 (es)
YU (3) YU43530B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62156230A (ja) * 1985-12-27 1987-07-11 Nippon Steel Corp 帯状物の蛇行修正方法

Also Published As

Publication number Publication date
HU190994B (en) 1986-12-28
BG40396A1 (en) 1986-12-15
ES8500617A1 (es) 1984-11-16
DK154209B (da) 1988-10-24
ES516723A0 (es) 1984-05-01
SU1507763A1 (ru) 1989-09-15
ES8407317A1 (es) 1984-10-01
FI79296B (fi) 1989-08-31
EP0086256B1 (de) 1985-08-21
EP0086256A1 (de) 1983-08-24
ATE15031T1 (de) 1985-09-15
DK464982A (da) 1983-04-22
FI79296C (fi) 1989-12-11
FI823563A0 (fi) 1982-10-18
CS247552B1 (en) 1987-01-15
ES529193A0 (es) 1984-11-16
DK154209C (da) 1989-03-20
ES529192A0 (es) 1984-10-01
YU235682A (en) 1985-08-31
NO155052C (no) 1987-02-04
NO823477L (no) 1983-04-22
DD204248A1 (de) 1983-11-23
DE3265640D1 (en) 1985-09-26
YU43530B (en) 1989-08-31
JPS6311347B2 (es) 1988-03-14
JPS58131946A (ja) 1983-08-06
FI823563L (fi) 1983-04-22
YU66685A (en) 1985-10-31
NO155052B (no) 1986-10-27
YU66785A (en) 1985-10-31

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