Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLCfiledCriticalBeecham Group PLC
Priority to ES516161ApriorityCriticalpatent/ES8400381A3/en
Publication of ES516161A0publicationCriticalpatent/ES516161A0/en
Publication of ES8400381A3publicationCriticalpatent/ES8400381A3/en
Process comprises decarboxylation of a beta-ceto acid of formula (I): (R1 is H or methyl and the dotted line represents 2 H atoms or a 2nd bond). The ceto gp. can then be reduced to an alcohol gp. - The prods., formed through decarboxylation e.g. by heating in acid medium and used as antiinflammatories, are of formula (II): (A1 is CO or CHOH).
ES516161A1982-10-011982-10-01Naphthalene derivs. prepn. as antiinflammatory agents
ExpiredES8400381A3
(en)