ES8400104A1 - "procedimiento para la preparacion de alcohiltioacilaminoacidos sustituidos". - Google Patents

"procedimiento para la preparacion de alcohiltioacilaminoacidos sustituidos".

Info

Publication number
ES8400104A1
ES8400104A1 ES509618A ES509618A ES8400104A1 ES 8400104 A1 ES8400104 A1 ES 8400104A1 ES 509618 A ES509618 A ES 509618A ES 509618 A ES509618 A ES 509618A ES 8400104 A1 ES8400104 A1 ES 8400104A1
Authority
ES
Spain
Prior art keywords
group
formula
pharmaceutical compositions
acids
alkylthioacylamino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES509618A
Other languages
English (en)
Other versions
ES509618A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of ES509618A0 publication Critical patent/ES509618A0/es
Publication of ES8400104A1 publication Critical patent/ES8400104A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572—Five-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE ALCOHILTIOACILAMINOACI DOS Y DE SUS SALES, DE FORMULA (I), EN LA QUE R1, R2, R3, R4 Y X PUEDEN SER VARIOS TIPOS DE RADICALES.CONSISTE EN LA REACCION DE UN ACIDO ALCOHILTIOCARBOXILICO SUSTITUIDO DE FORMULA (II), CON UN AMINOACIDO DE FORMULA (III), EN LAS QUE TODOS LOS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN PRESENCIA DE AGENTES ACTIVADORES DE CARBOXILO Y DE COPULACION.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU EFECTO HIPOTENSOR.
ES509618A 1980-03-22 1982-02-16 "procedimiento para la preparacion de alcohiltioacilaminoacidos sustituidos". Expired ES8400104A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803011239 DE3011239A1 (de) 1980-03-22 1980-03-22 Substituierte alkylthioacylaminosaeuren, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen

Publications (2)

Publication Number Publication Date
ES509618A0 ES509618A0 (es) 1983-02-01
ES8400104A1 true ES8400104A1 (es) 1983-02-01

Family

ID=6098110

Family Applications (3)

Application Number Title Priority Date Filing Date
ES500553A Granted ES500553A0 (es) 1980-03-22 1981-03-20 Procedimiento para la preparacion de alcohiltioacilaminoaci-dos sustituidos
ES509619A Granted ES509619A0 (es) 1980-03-22 1982-02-16 "procedimiento para la preparacion de alcohiltioacilaminoacidos sustituidos".
ES509618A Expired ES8400104A1 (es) 1980-03-22 1982-02-16 "procedimiento para la preparacion de alcohiltioacilaminoacidos sustituidos".

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES500553A Granted ES500553A0 (es) 1980-03-22 1981-03-20 Procedimiento para la preparacion de alcohiltioacilaminoaci-dos sustituidos
ES509619A Granted ES509619A0 (es) 1980-03-22 1982-02-16 "procedimiento para la preparacion de alcohiltioacilaminoacidos sustituidos".

Country Status (11)

Country Link
EP (1) EP0036572A1 (es)
JP (1) JPS56150059A (es)
AU (1) AU6858881A (es)
DE (1) DE3011239A1 (es)
DK (1) DK127281A (es)
ES (3) ES500553A0 (es)
FI (1) FI810866L (es)
GB (1) GB2072671A (es)
IL (1) IL62445A0 (es)
NO (1) NO810941L (es)
ZA (1) ZA811866B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1258853A (en) * 1982-04-30 1989-08-29 Rudiger D. Haugwitz Substituted 4-phenoxy prolines

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU509899B2 (en) * 1976-02-13 1980-05-29 E.R. Squibb & Sons, Inc. Proline derivatives and related compounds
FR2395998A1 (fr) * 1977-06-29 1979-01-26 Yoshitomi Pharmaceutical Nouveaux derives de la thiazolidine et leur application dans le traitement de l'hypertension
US4283407A (en) * 1977-09-28 1981-08-11 Science Union Et Cie Thiopropionamides, and the pharmaceutical compositions
CA1109475A (en) * 1978-07-27 1981-09-22 Miguel A. Ondetti Thiopropanoylamino acid derivatives

Also Published As

Publication number Publication date
EP0036572A1 (de) 1981-09-30
ES8306138A1 (es) 1982-08-16
ES500553A0 (es) 1982-08-16
IL62445A0 (en) 1981-05-20
NO810941L (no) 1981-09-23
GB2072671A (en) 1981-10-07
FI810866L (fi) 1981-09-23
ZA811866B (en) 1982-11-24
ES509618A0 (es) 1983-02-01
ES8400105A1 (es) 1983-01-16
AU6858881A (en) 1981-10-01
ES509619A0 (es) 1983-01-16
JPS56150059A (en) 1981-11-20
DK127281A (da) 1981-09-23
DE3011239A1 (de) 1981-10-01

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