ES8308698A1 - Procedimiento para preparar una composicion penetrable por la piel a base de agentes terapeuticos sistematicamente activos - Google Patents

Procedimiento para preparar una composicion penetrable por la piel a base de agentes terapeuticos sistematicamente activos

Info

Publication number
ES8308698A1
ES8308698A1 ES511169A ES511169A ES8308698A1 ES 8308698 A1 ES8308698 A1 ES 8308698A1 ES 511169 A ES511169 A ES 511169A ES 511169 A ES511169 A ES 511169A ES 8308698 A1 ES8308698 A1 ES 8308698A1
Authority
ES
Spain
Prior art keywords
pharmaceutical compositions
topical pharmaceutical
skin
penetrable
difficultly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES511169A
Other languages
English (en)
Other versions
ES511169A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH2327/81A external-priority patent/CH653256A5/de
Priority claimed from CH2631/81A external-priority patent/CH647149A5/de
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES511169A0 publication Critical patent/ES511169A0/es
Publication of ES8308698A1 publication Critical patent/ES8308698A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

COMPOSICION PENETRANTE POR LA PIEL A BASE DE AGENTES TERAPEUTICOS SISTEMATICAMENTE ACTIVOS Y DE DIFICIL PENETRACION. ADEMAS DEL AGENTE FARMACOLOGICAMENTE ACTIVO QUE PUEDE SER DIFICILMENTE PENETRABLE EN LA PIEL, SE INCLUYEN EXCIPIENTES COMPATIBLES CON ESTA CAPACES DE FUNCIONAR COMO DISOLVENTES ORGANICOS INMISCIBLES EN AGUA, UN EMULSIONANTE Y UN CO-EMULSIONANTE. LOS INGREDIENTES SE CALIENTAN DE 60 A 95 C, SIN PASAR DE 100 C, ENFRIANDO POSTERIORMENTE HASTA 15 O 35 C PARA FORMAR UNA MICROEMULSION.
ES511169A 1981-04-06 1982-04-05 Procedimiento para preparar una composicion penetrable por la piel a base de agentes terapeuticos sistematicamente activos Expired ES8308698A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH2327/81A CH653256A5 (en) 1981-04-06 1981-04-06 Microemulsion for cutaneous use
CH2631/81A CH647149A5 (en) 1981-04-22 1981-04-22 Composition with 5-chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole for cutaneous use
CH327881 1981-05-20

Publications (2)

Publication Number Publication Date
ES511169A0 ES511169A0 (es) 1983-10-01
ES8308698A1 true ES8308698A1 (es) 1983-10-01

Family

ID=27173625

Family Applications (1)

Application Number Title Priority Date Filing Date
ES511169A Expired ES8308698A1 (es) 1981-04-06 1982-04-05 Procedimiento para preparar una composicion penetrable por la piel a base de agentes terapeuticos sistematicamente activos

Country Status (16)

Country Link
AU (1) AU564570B2 (es)
CA (1) CA1192496A (es)
DE (1) DE3212053A1 (es)
DK (1) DK155882A (es)
ES (1) ES8308698A1 (es)
FI (1) FI821123L (es)
FR (1) FR2502951B1 (es)
GB (2) GB2098865B (es)
GR (1) GR75462B (es)
IL (1) IL65424A0 (es)
IT (1) IT8220611A0 (es)
MY (1) MY8600571A (es)
NL (1) NL8201413A (es)
NZ (1) NZ200232A (es)
PT (1) PT74703B (es)
SE (1) SE8202172L (es)

Families Citing this family (67)

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CH655656B (es) * 1982-10-07 1986-05-15
CA1225594A (en) * 1983-05-20 1987-08-18 Jourge Heller Method for percutaneously administering physiologically active agents
DE3406497A1 (de) * 1984-02-23 1985-09-05 Mueller Bernhard Willi Werner Hochdisperse pharmazeutische mehrkomponentensysteme und verfahren zu ihrer herstellung
US5364628A (en) * 1985-05-31 1994-11-15 Sandoz Ltd. Pharmaceutical compositions
AU578275B2 (en) * 1984-03-01 1988-10-20 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Pharmaceutical compositions
US5639724A (en) * 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
JPS61280426A (ja) * 1985-06-04 1986-12-11 Ikeda Mohandou:Kk 消炎鎮痛用貼付剤
US4767625A (en) * 1985-09-02 1988-08-30 Kao Corporation Lamella type single phase liquid crystal composition and oil-base cosmetic compositions using the same
US4690774A (en) 1985-09-11 1987-09-01 Chesebrough Pond's Inc. Novel translucent water in oil emulsions
US4797272A (en) 1985-11-15 1989-01-10 Eli Lilly And Company Water-in-oil microemulsions for cosmetic uses
DE3805744C2 (de) * 1987-03-04 1999-09-23 Novartis Ag Phenylcarbamate zur Hemmung der Acetylcholinesterase
IL88076A (en) * 1987-10-28 1993-01-14 Nippon Shinyaku Co Ltd Fat emulsions as drug carriers
US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
KR0148748B1 (ko) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
US5342625A (en) * 1988-09-16 1994-08-30 Sandoz Ltd. Pharmaceutical compositions comprising cyclosporins
US5241925A (en) * 1988-12-27 1993-09-07 Dermamed Apparatus and techniques for administering veterinary medicaments
US5332577A (en) * 1988-12-27 1994-07-26 Dermamed Transdermal administration to humans and animals
US7081445B2 (en) 1989-02-20 2006-07-25 Novartis Ag Cyclosporin galenic forms
DE3908047A1 (de) * 1989-03-13 1990-09-20 Desitin Arzneimittel Gmbh Hochdisperse pharmazeutische zusammensetzung
US5324521A (en) * 1989-12-18 1994-06-28 Dermamed Systems for transdermal administration of medicaments
US5149719A (en) * 1990-04-27 1992-09-22 Minnesota Mining And Manufacturing Company Composition for transdermal penetration of medicaments
FR2673537B1 (fr) 1991-03-08 1993-06-11 Oreal Utilisation d'agents de penetration hydrophiles dans les compositions dermatologiques pour le traitement des onychomycoses, et compositions correspondantes.
DK0580778T3 (da) * 1991-04-19 2000-01-31 Lds Technologies Inc Konvertible mikroemulsionsformuleringer
US5688761A (en) * 1991-04-19 1997-11-18 Lds Technologies, Inc. Convertible microemulsion formulations
US6005001A (en) * 1991-05-20 1999-12-21 Novartis Ag (Formerly Sandoz Ag) Pharmaceutical composition
HU223343B1 (hu) * 1991-05-20 2004-06-28 Novartis Ag. Allil-amin-származékot tartalmazó gyógyászati készítmények és eljárás azok előállítására
GB9111611D0 (en) * 1991-05-30 1991-07-24 Sandoz Ltd Liposomes
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
GB9126209D0 (en) * 1991-12-10 1992-02-12 Orion Yhtymae Oy Drug formulations for parenteral use
WO1993011798A1 (en) * 1991-12-16 1993-06-24 Alza Corporation Improved formulations with hydrophobic permeation enhancers
US5629019A (en) * 1992-02-27 1997-05-13 Alza Corporation Formulations with hydrophobic permeation enhancers
DE69307505T2 (de) 1992-05-13 1997-07-24 Sandoz-Patent-Gmbh, 79539 Loerrach Opthalmische zusammensetzungen enthaltend ein cyclosporin
PT589843E (pt) 1992-09-25 2002-04-29 Novartis Ag Composicoes farmaceuticas contendo ciclosporinas
WO1994008610A1 (en) * 1992-10-16 1994-04-28 Smithkline Beecham Corporation Pharmaceutical emulsion compositions
EP0684832A4 (en) * 1993-02-17 1996-09-11 Smithkline Beecham Corp MICROEMULSIONS CONTAINING PHARMACEUTICAL COMPOSITIONS.
SK164796A3 (en) 1994-11-03 1997-06-04 Dresden Arzneimittel Novel cyclosporine preparation forms for oral administration of and process for producing them
DE4442999A1 (de) 1994-12-02 1996-06-05 Hexal Pharma Gmbh Pharmazeutische Zusammensetzung mit einem aktiven Loratidin-Metaboliten
DE19549852B4 (de) 1995-11-29 2009-06-04 Novartis Ag Cyclosporin enthaltende Präparate
US5958876A (en) * 1996-06-19 1999-09-28 Novartis Ag Cyclosporin-containing pharmaceutical compositions
PL190420B1 (pl) 1997-01-30 2005-12-30 Novartis Ag Twarda kapsułka żelatynowa zawierajaca kompozycjęfarmaceutyczną
US6187747B1 (en) 1997-09-08 2001-02-13 Panacea Biotech Limited Pharmaceutical composition comprising cyclosporin
US6008191A (en) * 1997-09-08 1999-12-28 Panacea Biotec Limited Pharmaceutical compositions containing cyclosporin
IN188719B (es) * 1997-09-08 2002-11-02 Panacea Biotec Ltd
US6346511B1 (en) 1997-09-08 2002-02-12 Panacea Biotec Limited Pharmaceutical composition comprising cyclosporin
UY25225A1 (es) 1997-10-29 2000-12-29 Smithkline Beecham Plc Derivados de pleuromutilina utiles como agentes antimicrobianos
US6391282B1 (en) * 1997-11-10 2002-05-21 Flemington Pharmaceutical Corp. Antihistamine sprays and ointments for relief of delayed contact dermatitis
DE19825856A1 (de) * 1998-06-10 1999-12-16 Labtec Gmbh Topische Arzneimittelzubereitung
EP1135150B1 (en) 1998-12-11 2012-10-17 Tris Pharma, Inc. Self-emulsifying compositions for drugs poorly soluble in water
US7374779B2 (en) * 1999-02-26 2008-05-20 Lipocine, Inc. Pharmaceutical formulations and systems for improved absorption and multistage release of active agents
US6294192B1 (en) * 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
WO2004112723A2 (en) * 2003-06-20 2004-12-29 Ronald Aung-Din Tropical therapy for the treatment of migraines, muscle sprains, muscle spasm, spasticity and related conditions
ATE474591T1 (de) 2003-12-08 2010-08-15 Cpex Pharmaceuticals Inc Pharmazeutische zusammensetzungen und verfahren für die insulinbehandlung
US7740875B2 (en) 2004-10-08 2010-06-22 Mediquest Therapeutics, Inc. Organo-gel formulations for therapeutic applications
US20060078580A1 (en) 2004-10-08 2006-04-13 Mediquest Therapeutics, Inc. Organo-gel formulations for therapeutic applications
US9308203B2 (en) * 2008-10-01 2016-04-12 Taiwan Biotech Co., Ltd. Pressure sensitive adhesive matrix device or system for the treatment or prevention of onychomycosis or tinea pedis
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
WO2016033556A1 (en) 2014-08-28 2016-03-03 Lipocine Inc. BIOAVAILABLE SOLID STATE (17-β)-HYDROXY-4-ANDROSTEN-3-ONE ESTERS
US20170246187A1 (en) 2014-08-28 2017-08-31 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
EP3435977A4 (en) 2016-04-01 2019-10-16 Therapeuticsmd, Inc. PHARMACEUTICAL COMPOSITION OF STEROID HORMONE
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
CA3078723A1 (en) 2016-11-28 2018-05-31 Nachiappan Chidambaram Oral testosterone undecanoate therapy

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH570401A5 (es) * 1972-05-09 1975-12-15 Wander Ag Dr A
GB1559811A (en) * 1975-07-28 1980-01-30 Sandoz Ltd Pharmaceutically active benzothiadiazole derivatives
CH632268A5 (de) * 1977-01-14 1982-09-30 Sandoz Ag Verfahren zur herstellung von neuen heterocyclylaminoderivaten.

Also Published As

Publication number Publication date
CA1192496A (en) 1985-08-27
GB2148711B (en) 1985-12-18
FR2502951A1 (fr) 1982-10-08
DE3212053A1 (de) 1982-10-21
ES511169A0 (es) 1983-10-01
GB2098865B (en) 1985-12-18
NL8201413A (nl) 1982-11-01
PT74703A (en) 1982-05-01
FI821123L (fi) 1982-10-07
IL65424A0 (en) 1982-07-30
DK155882A (da) 1982-12-10
NZ200232A (en) 1985-08-16
FI821123A0 (fi) 1982-03-31
MY8600571A (en) 1986-12-31
GB2148711A (en) 1985-06-05
GR75462B (es) 1984-07-20
GB8408654D0 (en) 1984-05-16
FR2502951B1 (fr) 1985-12-06
IT8220611A0 (it) 1982-04-06
SE8202172L (sv) 1982-10-07
GB2098865A (en) 1982-12-01
AU8233482A (en) 1982-10-14
AU564570B2 (en) 1987-08-20
PT74703B (en) 1984-05-30

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