ES8307723A1 - "procedimiento para la preparacion de nuevos 1-ariloxi-3-alcohilamino-2-propanoles". - Google Patents

"procedimiento para la preparacion de nuevos 1-ariloxi-3-alcohilamino-2-propanoles".

Info

Publication number
ES8307723A1
ES8307723A1 ES515245A ES515245A ES8307723A1 ES 8307723 A1 ES8307723 A1 ES 8307723A1 ES 515245 A ES515245 A ES 515245A ES 515245 A ES515245 A ES 515245A ES 8307723 A1 ES8307723 A1 ES 8307723A1
Authority
ES
Spain
Prior art keywords
carbon atoms
alkyl
lower alkyl
ring
alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES515245A
Other languages
English (en)
Other versions
ES515245A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim GmbH
Original Assignee
Boehringer Ingelheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim GmbH filed Critical Boehringer Ingelheim GmbH
Publication of ES515245A0 publication Critical patent/ES515245A0/es
Publication of ES8307723A1 publication Critical patent/ES8307723A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00Preparation of carboxylic acid nitriles
    • C07C253/30Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fats And Perfumes (AREA)
  • Medicinal Preparation (AREA)
  • Pyrrole Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Seasonings (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE 1-ARILOXI-3-ALCOHILAMINO-2-PROPANOLES Y DE SUS SALES DE ADICION DE ACIDO, DE FORMULA (I), EN LA QUE R<3 ES ALCOHILO C<1<-<1<0; Y R<1 Y R<2 PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UNA AMINA DE FORMULA NH<2R<3, EN LAS QUE Z ES EL GRUPO -CH-CH<2- O -CHOH-CH<2-HAL, SIENDO HAL UN HALOGENO; Y R<1, R<2 Y R<3 TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE POLAR, TAL COMO ETANOL, A LA TEMPERATURA DE REFLUJO. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE LA ANGINA DE PECHO Y ARRITMIAS CARDIACAS.
ES515245A 1981-08-26 1982-08-25 "procedimiento para la preparacion de nuevos 1-ariloxi-3-alcohilamino-2-propanoles". Expired ES8307723A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813133678 DE3133678A1 (de) 1981-08-26 1981-08-26 Neue l-aryloxy-3-alkylamino-2-propanole und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
ES515245A0 ES515245A0 (es) 1983-08-01
ES8307723A1 true ES8307723A1 (es) 1983-08-01

Family

ID=6140122

Family Applications (3)

Application Number Title Priority Date Filing Date
ES515245A Expired ES8307723A1 (es) 1981-08-26 1982-08-25 "procedimiento para la preparacion de nuevos 1-ariloxi-3-alcohilamino-2-propanoles".
ES520094A Expired ES8401454A1 (es) 1981-08-26 1983-02-25 Procedimiento para la preparacion de nuevos 1-ariloxi-3-alcohilamino-2-propanoles.
ES520095A Granted ES520095A0 (es) 1981-08-26 1983-02-25 Procedimiento para la preparacion de nuevos 1-ariloxi-3-alcohilamino-2-propanoles.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES520094A Expired ES8401454A1 (es) 1981-08-26 1983-02-25 Procedimiento para la preparacion de nuevos 1-ariloxi-3-alcohilamino-2-propanoles.
ES520095A Granted ES520095A0 (es) 1981-08-26 1983-02-25 Procedimiento para la preparacion de nuevos 1-ariloxi-3-alcohilamino-2-propanoles.

Country Status (19)

Country Link
US (1) US4442120A (es)
EP (1) EP0073016B1 (es)
JP (1) JPS5859957A (es)
KR (1) KR890000620B1 (es)
AT (1) ATE16700T1 (es)
AU (1) AU558338B2 (es)
CA (1) CA1165324A (es)
DE (2) DE3133678A1 (es)
DK (1) DK380482A (es)
ES (3) ES8307723A1 (es)
FI (1) FI75150C (es)
GR (1) GR77606B (es)
IE (1) IE54224B1 (es)
IL (1) IL66633A (es)
NO (1) NO152603C (es)
NZ (1) NZ201716A (es)
PH (1) PH19705A (es)
PT (1) PT75458A (es)
ZA (1) ZA826183B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6343516B1 (en) * 1998-01-16 2002-02-05 Texaco Inc. Multiphase flow sampling using an autotraversing sample probe

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1199037A (en) * 1967-09-27 1970-07-15 Ici Ltd Alkanolamine Derivatives
DE2503222A1 (de) * 1975-01-27 1976-07-29 Boehringer Sohn Ingelheim Verfahren zur herstellung von 1-aryl- oxy-3-n-substituierten aminopropanderivaten
DE3015991A1 (de) * 1980-04-25 1981-11-05 C.H. Boehringer Sohn, 6507 Ingelheim Neue 1-aryloxy-3-alkylamino-2-propanole und verfahren zur ihrer herstellung

Also Published As

Publication number Publication date
FI822912L (fi) 1983-02-27
EP0073016A1 (de) 1983-03-02
PT75458A (de) 1982-09-01
IE822047L (en) 1983-02-26
FI75150C (fi) 1988-05-09
IL66633A0 (en) 1982-12-31
ES520094A0 (es) 1983-12-01
DE3133678A1 (de) 1983-03-17
AU8771882A (en) 1983-03-03
FI822912A0 (fi) 1982-08-23
ES515245A0 (es) 1983-08-01
EP0073016B1 (de) 1985-11-27
CA1165324A (en) 1984-04-10
NZ201716A (en) 1986-02-21
US4442120A (en) 1984-04-10
ATE16700T1 (de) 1985-12-15
IE54224B1 (en) 1989-07-19
JPS5859957A (ja) 1983-04-09
KR840001129A (ko) 1984-03-28
ES8401454A1 (es) 1983-12-01
ES8401455A1 (es) 1983-12-01
ZA826183B (en) 1984-04-25
GR77606B (es) 1984-09-25
NO152603B (no) 1985-07-15
NO152603C (no) 1985-10-23
KR890000620B1 (ko) 1989-03-22
IL66633A (en) 1986-02-28
DK380482A (da) 1983-02-27
NO822220L (no) 1983-02-28
DE3267692D1 (en) 1986-01-09
PH19705A (en) 1986-06-16
FI75150B (fi) 1988-01-29
ES520095A0 (es) 1983-12-01
AU558338B2 (en) 1987-01-29

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