ES8303305A1 - "un procedimiento para preparar derivados de urea y tiourea". - Google Patents

"un procedimiento para preparar derivados de urea y tiourea".

Info

Publication number
ES8303305A1
ES8303305A1 ES512330A ES512330A ES8303305A1 ES 8303305 A1 ES8303305 A1 ES 8303305A1 ES 512330 A ES512330 A ES 512330A ES 512330 A ES512330 A ES 512330A ES 8303305 A1 ES8303305 A1 ES 8303305A1
Authority
ES
Spain
Prior art keywords
phenyl
loweralkyl
arylthioalkyl
ureas
aminoalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES512330A
Other languages
English (en)
Other versions
ES512330A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AH Robins Co Inc
Original Assignee
AH Robins Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AH Robins Co Inc filed Critical AH Robins Co Inc
Publication of ES8303305A1 publication Critical patent/ES8303305A1/es
Publication of ES512330A0 publication Critical patent/ES512330A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/28—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/43—Y being a hetero atom
    • C07C323/44—X or Y being nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/06—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms
    • C07C335/08—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE UREA Y TIOUREA Y DE SUS SALES DE ADICION FISIOLOGICAMENTE COMPATIBLES E HIDRATOS, DE FORMULA (I), EN LA QUE X ES OXIGENO O AZUFRE; Y AR, B, ALK , ALK , R , R Y R PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE UNA AMINA DE FORMULA AR-B-ALK -NH , EN LA QUE AR, B Y ALK SON LOS MISMOS QUE EN LA FORMULA (I), CON 1,1''-CARBONILDIIMIDAZOL O 1,1''-TIOCARBONILDIIMIDAZOL, EN UN DISOLVENTE ADECUADO; SEGUIDA DE LA REACCION CON UNA ALCOHILDIAMINA DE FORMULA R NH-ALK -NR R , EN LA QUE R , R , R Y ALK TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU EFECTO ANTIARRITMICO.
ES512330A 1981-05-20 1982-05-19 "un procedimiento para preparar derivados de urea y tiourea". Granted ES512330A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26527881A 1981-05-20 1981-05-20
US34545282A 1982-02-03 1982-02-03

Publications (2)

Publication Number Publication Date
ES8303305A1 true ES8303305A1 (es) 1983-02-01
ES512330A0 ES512330A0 (es) 1983-02-01

Family

ID=26951096

Family Applications (3)

Application Number Title Priority Date Filing Date
ES512328A Expired ES8303303A1 (es) 1981-05-20 1982-05-19 "un procedimiento para preparar derivados de urea y tiourea".
ES512330A Granted ES512330A0 (es) 1981-05-20 1982-05-19 "un procedimiento para preparar derivados de urea y tiourea".
ES512329A Expired ES8303304A1 (es) 1981-05-20 1982-05-19 "un procedimiento para preparar derivados de urea y tiourea".

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES512328A Expired ES8303303A1 (es) 1981-05-20 1982-05-19 "un procedimiento para preparar derivados de urea y tiourea".

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES512329A Expired ES8303304A1 (es) 1981-05-20 1982-05-19 "un procedimiento para preparar derivados de urea y tiourea".

Country Status (17)

Country Link
EP (1) EP0066415B1 (es)
KR (1) KR890001811B1 (es)
AU (1) AU544976B2 (es)
CA (1) CA1180013A (es)
DE (1) DE3266645D1 (es)
DK (1) DK228482A (es)
ES (3) ES8303303A1 (es)
FI (1) FI76557C (es)
GR (1) GR76412B (es)
HK (1) HK96986A (es)
IE (1) IE53342B1 (es)
IL (1) IL65567A (es)
IN (1) IN155992B (es)
NO (1) NO153848C (es)
NZ (1) NZ200669A (es)
PH (1) PH23473A (es)
PT (1) PT74930B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL74140A (en) * 1984-04-10 1988-05-31 Robins Co Inc A H Substituted n-((amino)alkyl)-1-pyrrolidine,-1-piperidine and-1-homopiperidine-carboxamides and pharmaceutical compositions containing them
US4895840A (en) * 1987-06-10 1990-01-23 A. H. Robins Company, Incorporated N-(aryl-,aryloxy-,arylthio-arylsulfinyl-and arylsulfonyl-)alkyl-N,N'-(or n'n')alkylaminoalkyl ureas and cyanoguanidines
FR2664269B1 (fr) * 1990-07-05 1992-10-02 Roussel Uclaf Nouveaux derives n-substitues d'alpha-mercapto alkylamines, leur procede de preparation, leur application a titre de medicaments et les compositions les renfermant.
WO2001023350A1 (en) * 1999-09-28 2001-04-05 Nihon Nohyaku Co., Ltd. Thioalkylamine derivatives and process for the preparation thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2832756A (en) * 1955-04-15 1958-04-29 Rohm & Haas Monomeric polymerizable ureido and thioureido compounds, methods for producing them and polymers thereof
FR2296406A1 (fr) * 1974-12-31 1976-07-30 Oreal Nouvelles compositions cosmetiques a base de derives sulfoxydes de la cysteamine
GB1604674A (en) * 1977-05-17 1981-12-16 Allen & Hanburys Ltd Aminoalkyl-benzene derivatives

Also Published As

Publication number Publication date
FI821776A0 (fi) 1982-05-19
NZ200669A (en) 1985-12-13
CA1180013A (en) 1984-12-27
IE821191L (en) 1982-11-20
ES512328A0 (es) 1983-02-01
KR890001811B1 (ko) 1989-05-23
NO821668L (no) 1982-11-22
GR76412B (es) 1984-08-10
IN155992B (es) 1985-04-20
NO153848B (no) 1986-02-24
KR830010057A (ko) 1983-12-24
DK228482A (da) 1982-11-21
HK96986A (en) 1986-12-19
NO153848C (no) 1986-06-04
ES512330A0 (es) 1983-02-01
EP0066415A3 (en) 1983-09-14
DE3266645D1 (de) 1985-11-07
IE53342B1 (en) 1988-10-26
AU544976B2 (en) 1985-06-27
ES8303303A1 (es) 1983-02-01
ES512329A0 (es) 1983-02-01
IL65567A (en) 1985-11-29
EP0066415A2 (en) 1982-12-08
IL65567A0 (en) 1982-07-30
FI76557C (fi) 1988-11-10
FI76557B (fi) 1988-07-29
AU8388182A (en) 1982-11-25
PT74930A (en) 1982-06-01
PT74930B (en) 1983-12-07
ES8303304A1 (es) 1983-02-01
PH23473A (en) 1989-08-07
EP0066415B1 (en) 1985-10-02

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