ES8301969A1 - Un procedimiento para la preparacion de compuestos - Google Patents

Un procedimiento para la preparacion de compuestos

Info

Publication number
ES8301969A1
ES8301969A1 ES505019A ES505019A ES8301969A1 ES 8301969 A1 ES8301969 A1 ES 8301969A1 ES 505019 A ES505019 A ES 505019A ES 505019 A ES505019 A ES 505019A ES 8301969 A1 ES8301969 A1 ES 8301969A1
Authority
ES
Spain
Prior art keywords
alkyl
group
hydroxy
substituted
sulphur
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES505019A
Other languages
English (en)
Other versions
ES505019A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ES8301969A1 publication Critical patent/ES8301969A1/es
Publication of ES505019A0 publication Critical patent/ES505019A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • C07D257/06Five-membered rings with nitrogen atoms directly attached to the ring carbon atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DEL TETRAZOL Y DE SUS SALES, HIDRATOS Y BIOPRECURSORES FISIOLOGICAMENTE ACEPTABLES, DE FORMULA (I), EN LA QUE ALK ES UN ALQUILENO C <003> ; Q, R , R , R , R , X E Y PUEDEN SER VARIOS TIPOS DE RADICALES; N VALE 1-3 Y M VALE 2-5. CONSISTE EN LA REACCION DE REDUCCION DE UN COMPUESTO DE FORMULA (II) EN LA QUE DA, DB Y DC PUEDEN SER VARIOS TIPOS DE RADICALES Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO POR TRATAMIENTO CON UN HIDRURO METALICO COMPLEJO EN UN DISOLVENTE ORGANICO TIPO ETER A UNA TEMPERATURA ENTRE 20<025>C Y LA DE REFLUJO DE LA MEZCLA DE REACCION. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO ANTAGONISTAS SELECTIVOS H DE HISTAMINA.
ES505019A 1980-08-27 1981-08-27 Un procedimiento para la preparacion de compuestos Granted ES505019A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8027743 1980-08-27

Publications (2)

Publication Number Publication Date
ES8301969A1 true ES8301969A1 (es) 1982-12-16
ES505019A0 ES505019A0 (es) 1982-12-16

Family

ID=10515680

Family Applications (2)

Application Number Title Priority Date Filing Date
ES505019A Granted ES505019A0 (es) 1980-08-27 1981-08-27 Un procedimiento para la preparacion de compuestos
ES515331A Expired ES8306747A1 (es) 1980-08-27 1982-08-27 Un procedimiento para la preparacion de derivados del tetrazol.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES515331A Expired ES8306747A1 (es) 1980-08-27 1982-08-27 Un procedimiento para la preparacion de derivados del tetrazol.

Country Status (13)

Country Link
EP (1) EP0049049B1 (es)
JP (1) JPS5777679A (es)
KR (2) KR840001774B1 (es)
AU (1) AU7475081A (es)
CA (1) CA1186314A (es)
DE (1) DE3172914D1 (es)
DK (1) DK381581A (es)
ES (2) ES505019A0 (es)
FI (1) FI812663L (es)
GB (1) GB2082584B (es)
IE (1) IE51576B1 (es)
NZ (1) NZ198192A (es)
ZA (1) ZA815962B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4585781A (en) * 1982-12-31 1986-04-29 Glaxo Group Limited Heterocyclic derivatives
US5260445A (en) * 1987-09-04 1993-11-09 Beecham Group P.L.C. 2,4-thiazolidinediones
US5262433A (en) * 1991-08-06 1993-11-16 Wakamoto Pharmaceutical Co., Ltd. Tetrazoleacetic acid derivatives and method of aldose reductase inhibition therewith
USRE39384E1 (en) 1993-09-01 2006-11-07 Smithkline Beecham P.L.C. Substituted thiazolidinedione derivatives
CN101903174B (zh) 2008-08-11 2014-04-02 北京大学 超疏水聚二甲基硅氧烷及其制备方法
CN101835739B (zh) 2008-08-29 2013-10-09 北京大学 整合了光敏引发剂的聚(二甲基硅氧烷)
CN101790523A (zh) 2008-08-29 2010-07-28 北京大学 用于复杂图案形成的光敏pdms
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO800583L (no) * 1979-03-02 1980-09-03 Glaxo Group Ltd Fremgangsmaate for fremstilling av farmakologisk aktive triazolderivater
EP0029306B1 (en) * 1979-10-23 1984-07-25 Glaxo Group Limited Aminoalkyl compounds, their production and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
FI812663L (fi) 1982-02-28
ZA815962B (en) 1983-04-27
AU7475081A (en) 1982-03-04
JPS5777679A (en) 1982-05-15
GB2082584B (en) 1984-08-08
KR850002012A (ko) 1985-04-10
KR840001774B1 (ko) 1984-10-19
NZ198192A (en) 1985-02-28
GB2082584A (en) 1982-03-10
KR840001775B1 (ko) 1984-10-19
CA1186314A (en) 1985-04-30
KR830006243A (ko) 1983-09-20
IE51576B1 (en) 1987-01-21
ES505019A0 (es) 1982-12-16
IE811965L (en) 1982-02-27
ES515331A0 (es) 1983-06-01
EP0049049B1 (en) 1985-11-13
ES8306747A1 (es) 1983-06-01
EP0049049A1 (en) 1982-04-07
DE3172914D1 (en) 1985-12-19
DK381581A (da) 1982-02-28

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